{"id":10315,"date":"2013-12-22T17:00:00","date_gmt":"2013-12-22T10:00:00","guid":{"rendered":"https:\/\/yhoccongdong.org\/du-an-khac\/propylthioracil-thuoc-khang-giap\/"},"modified":"2024-03-17T02:33:51","modified_gmt":"2024-03-16T19:33:51","slug":"propylthioracil-thuoc-khang-giap","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/du-an-khac\/propylthioracil-thuoc-khang-giap\/","title":{"rendered":"Propylthioracil &#8211; Thu\u1ed1c kh\u00e1ng gi\u00e1p"},"content":{"rendered":"<h2 id=\"ten-chung-quoc-te-propylthioracil\">    T\u00ean chung qu\u1ed1c t\u1ebf Propylthioracil   <\/h2>\n<p>    Propylthiouracil.   <\/p>\n<h2 id=\"dang-thuoc-va-ham-luong-propylthioracil\">    D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng Propylthioracil   <\/h2>\n<p>    Vi\u00ean n\u00e9n 50 mg.   <\/p>\n<p style=\"text-align: center;\">    <img decoding=\"async\" alt=\"propylthioracil-thuoc-khang-giap\" src=\"\/\/yhoccongdong.org\/Documents\/1143_propylthioracil-thuoc-khang-giap.jpg\" style=\"width: 400px; height: 300px;\"\/>   <\/p>\n<p style=\"text-align: center;\">    H\u00ecnh Propylthioracil Thu\u1ed1c Kh\u00e1ng Gi\u00e1p   <\/p>\n<h2 id=\"chi-dinh-propylthioracil\">    Ch\u1ec9 \u0111\u1ecbnh Propylthioracil   <\/h2>\n<p>    \u0110i\u1ec1u tr\u1ecb c\u01b0\u1eddng gi\u00e1p \u0111\u1ec3 chu\u1ea9n b\u1ecb ph\u1eabu thu\u1eadt ho\u1eb7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng iod ph\u00f3ng x\u1ea1; x\u1eed tr\u00ed c\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p.   <\/p>\n<h2 id=\"chong-chi-dinh-propylthioracil\">    Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh Propylthioracil   <\/h2>\n<p>    B\u1ecb m\u1eafc c\u00e1c b\u1ec7nh v\u1ec1 m\u00e1u (m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, thi\u1ebfu m\u00e1u b\u1ea5t s\u1ea3n); vi\u00eam gan; m\u1eabn c\u1ea3m v\u1edbi propylthiouracil ho\u1eb7c m\u1ed9t th\u00e0nh ph\u1ea7n c\u1ee7a thu\u1ed1c, cho con b\u00fa (Ph\u1ee5 l\u1ee5c 3).   <\/p>\n<h2 id=\"than-trong-propylthioracil\">    Th\u1eadn tr\u1ecdng Propylthioracil   <\/h2>\n<p>    Ng\u01b0\u1eddi c\u00f3 b\u01b0\u1edbu c\u1ed5 to; mang thai (Ph\u1ee5 l\u1ee5c 2); suy gan (Ph\u1ee5 l\u1ee5c 5); suy th\u1eadn (Ph\u1ee5 l\u1ee5c 4); ng\u01b0\u1eddi tr\u00ean 40 tu\u1ed5i; ph\u1ea3i theo d\u00f5i ch\u1eb7t ch\u1ebd v\u1ec1 huy\u1ebft h\u1ecdc (\u0111\u1ebfm c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o m\u00e1u, c\u00f4ng th\u1ee9c b\u1ea1ch c\u1ea7u) nh\u1ea5t l\u00e0 trong giai \u0111o\u1ea1n \u0111\u1ea7u d\u00f9ng thu\u1ed1c; theo d\u00f5i c\u00e1c tri\u1ec7u ch\u1ee9ng nhi\u1ec5m khu\u1ea9n; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c kh\u00e1c c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m b\u1ea1ch c\u1ea7u; theo d\u00f5i th\u1eddi gian prothrombin, th\u1eddi gian ch\u1ea3y m\u00e1u; ch\u1ee9c n\u0103ng gan. Ng\u01b0\u1eddi b\u1ec7nh ph\u1ea3i th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129 khi b\u1ecb \u0111au h\u1ecdng, lo\u00e9t mi\u1ec7ng, s\u1ed1t.   <\/p>\n<h2 id=\"lieu-luong-va-cach-dung-propylthioracil\">    Li\u1ec1u l\u01b0\u1ee3ng v\u00e0 c\u00e1ch d\u00f9ng Propylthioracil   <\/h2>\n<p>    D\u00f9ng theo \u0111\u01b0\u1eddng u\u1ed1ng, ng\u00e0y u\u1ed1ng l\u00e0m 3 l\u1ea7n c\u00e1ch nhau 8 gi\u1edd. \u0110i\u1ec1u tr\u1ecb c\u01b0\u1eddng gi\u00e1p: Li\u1ec1u ban \u0111\u1ea7u cho ng\u01b0\u1eddi l\u1edbn l\u00e0 300 &#8211; 450 mg\/ng\u00e0y, chia l\u00e0m 3 l\u1ea7n; tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng c\u00f3 th\u1ec3 d\u00f9ng li\u1ec1u ban \u0111\u1ea7u l\u00e0 600 &#8211; 1200 mg\/ng\u00e0y. Khi \u0111\u00e3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c th\u00ec ti\u1ebfp t\u1ee5c d\u00f9ng li\u1ec1u ban \u0111\u1ea7u trong kho\u1ea3ng 2 th\u00e1ng r\u1ed3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u theo dung n\u1ea1p thu\u1ed1c v\u00e0 \u0111\u00e1p \u1ee9ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh. Li\u1ec1u duy tr\u00ec th\u01b0\u1eddng b\u1eb1ng 1\/3 \u0111\u1ebfn 2\/3 li\u1ec1u ban \u0111\u1ea7u (100 &#8211; 150 mg\/ng\u00e0y). Li\u1ec1u ban \u0111\u1ea7u \u1edf tr\u1ebb em l\u00e0 5 &#8211; 7 mg\/kg\/ng\u00e0y (ho\u1eb7c 50 &#8211; 150 mg\/ng\u00e0y cho tr\u1ebb 6 &#8211; 10 tu\u1ed5i; 150 &#8211; 300 mg ho\u1eb7c 150 mg\/m2\/ng\u00e0y cho tr\u1ebb tr\u00ean 10 tu\u1ed5i), chia th\u00e0nh li\u1ec1u nh\u1ecf, u\u1ed1ng c\u00e1ch nhau 8 gi\u1edd. Li\u1ec1u duy tr\u00ec \u1edf tr\u1ebb em: 1\/3 \u0111\u1ebfn 2\/3 li\u1ec1u ban \u0111\u1ea7u, chia th\u00e0nh nhi\u1ec1u li\u1ec1u nh\u1ecf u\u1ed1ng trong ng\u00e0y. \u0110i\u1ec1u tr\u1ecb c\u01a1n nhi\u1ec5m \u0111\u1ed9c gi\u00e1p \u1edf ng\u01b0\u1eddi l\u1edbn (do chuy\u00ean khoa ch\u1ec9 \u0111\u1ecbnh): U\u1ed1ng 200 mg\/l\u1ea7n, ng\u00e0y th\u1ee9 nh\u1ea5t u\u1ed1ng c\u00e1c l\u1ea7n c\u00e1ch nhau 4 &#8211; 6 gi\u1edd, khi \u0111\u00e3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c th\u00ec gi\u1ea3m d\u1ea7n xu\u1ed1ng li\u1ec1u th\u01b0\u1eddng d\u00f9ng.   <\/p>\n<p>    <em>     C\u1ea7n gi\u1ea3m li\u1ec1u \u1edf ng\u01b0\u1eddi cao tu\u1ed5i    <\/em>   : Li\u1ec1u ban \u0111\u1ea7u 150 &#8211; 300 mg\/ng\u00e0y. Ng\u01b0\u1eddi suy th\u1eadn: \u0110\u1ed9 thanh th\u1ea3i creatinin 10 &#8211; 50 ml\/ph\u00fat d\u00f9ng 75% li\u1ec1u th\u01b0\u1eddng d\u00f9ng; \u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 10 ml\/ph\u00fat d\u00f9ng 50% li\u1ec1u th\u01b0\u1eddng d\u00f9ng.   <\/p>\n<h2 id=\"tac-dung-khong-mong-muon-propylthioracil\">    T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n Propylthioracil   <\/h2>\n<p>    Bu\u1ed3n n\u00f4n, n\u00f4n; \u0111au th\u01b0\u1ee3ng v\u1ecb; nh\u1ee9c \u0111\u1ea7u; s\u1ed1t; \u0111au kh\u1edbp; ng\u1ee9a; ph\u00f9; gi\u1ea3m to\u00e0n th\u1ec3 huy\u1ebft c\u1ea7u; m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t (n\u1eb7ng); r\u1ee5ng t\u00f3c, vi\u00eam da tr\u00f3c; v\u00e0ng da; vi\u00eam gan. H\u1ed9i ch\u1ee9ng gi\u1ed1ng lupus ban \u0111\u1ecf.   <\/p>\n<p>    <em>     X\u1eed tr\u00ed ADR:    <\/em>    N\u1ebfu b\u1ecb gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, thi\u1ebfu m\u00e1u th\u00ec ph\u1ea3i ng\u1eebng thu\u1ed1c, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, d\u00f9ng li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3; ng\u1eebng h\u1eb3n thu\u1ed1c n\u1ebfu trans- aminase gan cao h\u01a1n b\u00ecnh th\u01b0\u1eddng 3 l\u1ea7n; theo d\u00f5i ch\u1ee9c n\u0103ng gi\u00e1p \u0111\u1ec3 s\u1edbm \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.   <\/p>\n<h2 id=\"qua-lieu-va-xu-tri-propylthioracil\">    Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed Propylthioracil   <\/h2>\n<p>    \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3; g\u00e2y n\u00f4n; r\u1eeda d\u1ea1 d\u00e0y; ch\u1ed1ng nhi\u1ec5m khu\u1ea9n; truy\u1ec1n m\u00e1u t\u01b0\u01a1i; ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng ngh\u1ec9 ng\u01a1i th\u00edch h\u1ee3p n\u1ebfu b\u1ecb vi\u00eam gan; c\u00f3 th\u1ec3 d\u00f9ng gi\u1ea3m \u0111au, an th\u1ea7n, truy\u1ec1n d\u1ecbch.   <\/p>\n<h2 id=\"do-on-dinh-va-bao-quan-propylthioracil\">    \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n Propylthioracil   <\/h2>\n<p>    B\u1ea3o qu\u1ea3n trong l\u1ecd th\u1eadt k\u00edn \u1edf nhi\u1ec7t \u0111\u1ed9 15 &#8211; 30    <sup>     o    <\/sup>    C. Ch\u00fa th\u00edch: Methylthiouracil (MTU), BTU (Benzylthiouracil) l\u00e0 thu\u1ed1c kh\u00e1ng gi\u00e1p c\u0169ng thu\u1ed9c nh\u00f3m thiouracil, r\u1ea5t th\u00f4ng d\u1ee5ng tr\u01b0\u1edbc \u0111\u00e2y nh\u01b0ng hi\u1ec7n kh\u00f4ng c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng do c\u00f3 nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 nay \u0111\u01b0\u1ee3c thay th\u1ebf b\u1eb1ng propylthiouracil.   <\/p>\n<\/p>\n<p>    http:\/\/nidqc.org.vn\/duocthu\/592\/   <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Propylthioracil &#8211; Thu\u1ed1c kh\u00e1ng gi\u00e1p ch\u1eefa tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au h\u1ecdng, nh\u1ee9c kh\u1edbp&#8230;.<\/p>\n","protected":false},"author":143,"featured_media":10316,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5442,5385,5441,5316,5384,5317],"tags":[],"series":[],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - 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