{"id":10384,"date":"2013-12-22T17:00:00","date_gmt":"2013-12-22T10:00:00","guid":{"rendered":"https:\/\/yhoccongdong.org\/du-an-khac\/acetylcystein-thuoc-giai-doc-paracetamol\/"},"modified":"2024-03-17T02:35:50","modified_gmt":"2024-03-16T19:35:50","slug":"acetylcystein-thuoc-giai-doc-paracetamol","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/du-an-khac\/acetylcystein-thuoc-giai-doc-paracetamol\/","title":{"rendered":"Acetylcystein &#8211; Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Paracetamol"},"content":{"rendered":"<p>    Thu\u1ed1c k\u00edch th\u00edch gan s\u1ea3n xu\u1ea5t glutathion, 1 ch\u1ea5t c\u1ea7n thi\u1ebft \u0111\u1ec3 l\u00e0m b\u1ea5t ho\u1ea1t ch\u1ea5t chuy\u1ec3n ho\u00e1 trung gian c\u1ee7a paracetamol \u0111\u1ed9c cho gan.   <\/p>\n<h2 id=\"ten-chung-quoc-te-acetylcystein\">    T\u00ean chung qu\u1ed1c t\u1ebf Acetylcystein   <\/h2>\n<p>    Acetylcysteine   <\/p>\n<h2 id=\"dang-thuoc-va-ham-luong-acetylcystein\">    D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng Acetylcystein   <\/h2>\n<p>    Dung d\u1ecbch u\u1ed1ng 10% (100 mg\/ml), 20% (200 mg\/ml).   <\/p>\n<p>    Dung d\u1ecbch ti\u00eam 20%, \u1ed1ng 10 ml.   <\/p>\n<h2 id=\"chi-dinh-acetylcystein\">    Ch\u1ec9 \u0111\u1ecbnh Acetylcystein   <\/h2>\n<p>    Qu\u00e1 li\u1ec1u paracetamol.   <\/p>\n<h2 id=\"chong-chi-dinh-acetylcystein\">    Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh Acetylcystein   <\/h2>\n<p>    M\u1eabn c\u1ea3m v\u1edbi thu\u1ed1c.   <\/p>\n<h2 id=\"than-trong-acetylcystein\">    Th\u1eadn tr\u1ecdng Acetylcystein   <\/h2>\n<p>    Hen.   <\/p>\n<h2 id=\"lieu-luong-va-cach-dung-acetylcystein\">    Li\u1ec1u l\u01b0\u1ee3ng v\u00e0 c\u00e1ch d\u00f9ng Acetylcystein   <\/h2>\n<\/p>\n<p>    <em>     C\u00e1ch d\u00f9ng:    <\/em>    Pha lo\u00e3ng dung d\u1ecbch ti\u00eam b\u1eb1ng dung d\u1ecbch glucose 5% \u0111\u1ec3 ti\u00eam truy\u1ec1n.   <\/p>\n<p>    <em>     Li\u1ec1u d\u00f9ng:    <\/em>   <\/p>\n<p>    Ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch, ng\u01b0\u1eddi l\u1edbn, ban \u0111\u1ea7u 150 mg\/kg pha v\u1edbi 200 ml dung d\u1ecbch glucose 5%, truy\u1ec1n trong 15 ph\u00fat; sau \u0111\u00f3 50 mg\/kg trong 500 ml glucose 5%, truy\u1ec1n trong 4 gi\u1edd; sau c\u00f9ng 100 mg\/kg trong 1000 ml glucose 5% truy\u1ec1n trong 16 gi\u1edd. \u0110\u1ed1i v\u1edbi tr\u1ebb em, th\u1ec3 t\u00edch d\u1ecbch truy\u1ec1n c\u1ea7n ph\u1ea3i gi\u1ea3m \u0111\u1ec3 tr\u00e1nh t\u0103ng g\u00e1nh d\u1ecbch truy\u1ec1n. Li\u1ec1u acetylcystein v\u1eabn gi\u1ed1ng nh\u01b0 li\u1ec1u ng\u01b0\u1eddi l\u1edbn.   <\/p>\n<p>    Ho\u1eb7c u\u1ed1ng: Li\u1ec1u \u0111\u1ea7u ti\u00ean 140 mg\/kg, d\u01b0\u1edbi d\u1ea1ng dung d\u1ecbch 5%, ti\u1ebfp theo l\u00e0 70 mg\/kg, u\u1ed1ng c\u00e1ch nhau 4 gi\u1edd m\u1ed9t l\u1ea7n, t\u1ed5ng c\u1ed9ng 17 l\u1ea7n. Acetylcystein \u0111\u01b0\u1ee3c th\u00f4ng b\u00e1o r\u1ea5t hi\u1ec7u qu\u1ea3 khi d\u00f9ng trong v\u00f2ng 8 gi\u1edd sau khi b\u1ecb qu\u00e1 li\u1ec1u paracetamol. Hi\u1ec7u qu\u1ea3 gi\u1ea3m sau th\u1eddi gian \u0111\u00f3, nh\u01b0ng g\u1ea7n \u0111\u00e2y cho r\u1eb1ng \u0111i\u1ec1u tr\u1ecb ch\u1eadm t\u1edbi 24 gi\u1edd sau v\u1eabn c\u00f3 \u00edch.   <\/p>\n<h2 id=\"tac-dung-khong-mong-muon-acetylcystein\">    T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n Acetylcystein   <\/h2>\n<p>    Ph\u00e1t ban, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7.\u00a0X\u1eed tr\u00ed: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u00f4n b\u1eb1ng c\u00e1ch d\u00f9ng dung d\u1ecbch acetylcystein pha lo\u00e3ng. Ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7: Adrenalin dung d\u1ecbch 1\/1000, 0,3 &#8211; 0,5 ml ti\u00eam d\u01b0\u1edbi da, th\u1edf oxygen, truy\u1ec1n d\u1ecbch, h\u00edt thu\u1ed1c ch\u1ee7 v\u1eadn beta-adrenergic n\u1ebfu co th\u1eaft ph\u1ebf qu\u1ea3n, ti\u00eam t\u0129nh m\u1ea1ch 500 mg hydrocortison ho\u1eb7c 125 mg methylprednison. C\u00f3 th\u1ec3 d\u1ef1 ph\u00f2ng ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (3% khi ti\u00eam t\u0129nh m\u1ea1ch) b\u1eb1ng c\u00e1ch cho tr\u01b0\u1edbc kh\u00e1ng histamin.   <\/p>\n<h2 id=\"qua-lieu-va-xu-tri-acetylcystein\">    Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed Acetylcystein   <\/h2>\n<\/p>\n<p>    Qu\u00e1 li\u1ec1u c\u00f3 tri\u1ec7u ch\u1ee9ng gi\u1ed1ng nh\u01b0 ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7 nh\u01b0ng n\u1eb7ng h\u01a1n nhi\u1ec1u, \u0111\u1eb7c bi\u1ec7t gi\u1ea3m huy\u1ebft \u00e1p, suy h\u00f4 h\u1ea5p, \u0111\u00f4ng m\u00e1u r\u1ea3i r\u00e1c n\u1ed9i m\u1ea1ch, suy th\u1eadn v\u00e0 t\u1eed vong. Qu\u00e1 li\u1ec1u acetylcystein x\u1ea3y ra khi ti\u00eam truy\u1ec1n qu\u00e1 nhanh v\u00e0 v\u1edbi li\u1ec1u qu\u00e1 cao.   <\/p>\n<p>    X\u1eed tr\u00ed: \u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3.   <\/p>\n<h2 id=\"do-on-dinh-va-bao-quan-acetylcystein\">    \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n Acetylcystein   <\/h2>\n<p>    B\u1ea3o qu\u1ea3n trong l\u1ecd \u0111\u00f3ng k\u00edn \u1edf 15 &#8211; 30    <sup>     o    <\/sup>    C. Sau khi ti\u1ebfp x\u00fac v\u1edbi kh\u00f4ng kh\u00ed, dung d\u1ecbch ph\u1ea3i b\u1ea3o qu\u1ea3n \u1edf 2 &#8211; 8    <span class=\"do_c\">     o    <\/span>    C \u0111\u1ec3 l\u00e0m ch\u1eadm oxy ho\u00e1 v\u00e0 ph\u1ea3i d\u00f9ng trong v\u00f2ng 96 gi\u1edd. Ph\u1ea3i pha lo\u00e3ng dung d\u1ecbch ngay tr\u01b0\u1edbc khi d\u00f9ng v\u00e0 dung d\u1ecbch \u0111\u00e3 pha lo\u00e3ng ch\u1ec9 \u1ed5n \u0111\u1ecbnh trong 1 gi\u1edd.   <\/p>\n<\/p>\n<p>    http:\/\/nidqc.org.vn\/duocthu\/222\/   <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Acetylcystein l\u00e0 Acetylcysteine. Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Paracetamol. Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c v\u00e0 c\u00e1c thu\u1ed1c d\u00f9ng trong nhi\u1ec5m \u0111\u1ed9c.<\/p>\n","protected":false},"author":143,"featured_media":10385,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5316,5578,5510,5513,5317],"tags":[],"series":[],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Acetylcystein - Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Paracetamol - D\u1ef1 \u00e1n kh\u00e1c<\/title>\n<meta name=\"description\" content=\"Acetylcystein - Thu\u1ed1c gi\u1ea3i \u0111\u1ed9c Paracetamol - D\u1ef1 \u00e1n kh\u00e1c\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/du-an-khac\/acetylcystein-thuoc-giai-doc-paracetamol\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acetylcystein - 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