Hi\u0300nh\u00a0Indinavir – Thu\u1ed1c \u1ee9c ch\u1ebf protease <\/em> <\/p>\n Ch\u1ec9 \u0111\u1ecbnh Indinavir <\/h2>\n
Nhi\u1ec5m HIV, k\u1ebft h\u1ee3p v\u1edbi 2 thu\u1ed1c nucleosid \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c v\u00e0 th\u01b0\u1eddng d\u00f9ng v\u1edbi ritonavir li\u1ec1u th\u1ea5p \u0111\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng. <\/p>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh Indinavir <\/h2>\n
Qu\u00e1 m\u1eabn v\u1edbi indinavir. <\/p>\n
Th\u1eadn tr\u1ecdng Indinavir <\/h2>\n
Suy gan (Ph\u1ee5 l\u1ee5c 5); u\u1ed1ng nhi\u1ec1u n\u01b0\u1edbc \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 s\u1ecfi th\u1eadn; \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng; b\u1ec7nh \u01b0a ch\u1ea3y m\u00e1u (hemophili); th\u1eddi k\u1ef3 mang thai v\u00e0 cho con b\u00fa (xem ph\u1ea7n chung \u1edf tr\u00ean v\u00e0 Ph\u1ee5 l\u1ee5c 2 v\u00e0 3); \u1ee9c ch\u1ebf chuy\u1ec3n ho\u00e1 nhi\u1ec1u thu\u1ed1c n\u1ebfu \u0111i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p. <\/p>\n
T\u01b0\u01a1ng t\u00e1c thu\u1ed1c Indinavir <\/h2>\n
(Ph\u1ee5 l\u1ee5c 1). <\/p>\n
Li\u1ec1u l\u01b0\u1ee3ng v\u00e0 c\u00e1ch d\u00f9ng Indinavir <\/h2>\n
Nhi\u1ec5m HIV <\/em> (k\u1ebft h\u1ee3p v\u1edbi nucleosid \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c v\u00e0 li\u1ec1u th\u1ea5p ritonavir \u0111\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng): Ng\u01b0\u1eddi l\u1edbn, u\u1ed1ng 800 mg indinavir + 100 mg ritonavir\/l\u1ea7n, ng\u00e0y 2 l\u1ea7n; <\/p>\n Nhi\u1ec5m HIV <\/em> (k\u1ebft h\u1ee3p v\u1edbi nucleosid \u1ee9c ch\u1ebf enzym sao ch\u00e9p ng\u01b0\u1ee3c nh\u01b0ng kh\u00f4ng d\u00f9ng ritonavir): Ng\u01b0\u1eddi l\u1edbn u\u1ed1ng 800 mg m\u1ed7i 8 gi\u1edd; tr\u1ebb em v\u00e0 thi\u1ebfu ni\u00ean 4 – 17 tu\u1ed5i, 500 mg\/m2 m\u1ed7i 8 gi\u1edd (t\u1ed1i \u0111a 800 mg m\u1ed7i 8 gi\u1edd); tr\u1ebb em d\u01b0\u1edbi 4 tu\u1ed5i, \u0111\u1ed9 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 ch\u01b0a x\u00e1c \u0111\u1ecbnh. <\/p>\n L\u1eddi khuy\u00ean: <\/em> D\u00f9ng thu\u1ed1c 1 gi\u1edd tr\u01b0\u1edbc b\u1eefa \u0103n ho\u1eb7c 2 gi\u1edd sau b\u1eefa \u0103n; c\u00f3 th\u1ec3 d\u00f9ng th\u1ee9c \u0103n nh\u1eb9 \u00edt m\u1ee1; kh\u00f4ng n\u00ean \u0103n b\u01b0\u1edfi trong khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng indi- navir; khi ph\u1ed1i h\u1ee3p v\u1edbi didanosin, n\u00ean u\u1ed1ng m\u1ed7i thu\u1ed1c c\u00e1ch 1 gi\u1edd (thu\u1ed1c ch\u1ed1ng acid trong didanosin l\u00e0m gi\u1ea3m h\u1ea5p th\u1ee5 indinavir). <\/p>\n T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n Indinavir <\/h2>\n
Bu\u1ed3n n\u00f4n, n\u00f4n, \u1ec9a ch\u1ea3y, \u0111\u1ea7y b\u1ee5ng, r\u1ed1i lo\u1ea1n ti\u00eau ho\u00e1, \u0111\u1ea7y h\u01a1i, vi\u00eam t\u1ee5y, kh\u00f4 mi\u1ec7ng, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c; nh\u1ee9c \u0111\u1ea7u, cho\u00e1ng v\u00e1ng, m\u1ea5t ng\u1ee7, \u0111au c\u01a1, vi\u00eam c\u01a1, ti\u00eau c\u01a1 v\u00e2n, suy nh\u01b0\u1ee3c, gi\u1ea3m c\u1ea3m gi\u00e1c, d\u1ecb c\u1ea3m, t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, ngo\u1ea1i ban (g\u1ed3m c\u1ea3 h\u1ed9i ch\u1ee9ng Stevens-Johnson), ng\u1ee9a, da kh\u00f4, t\u0103ng nhi\u1ec5m h\u1eafc t\u1ed1, r\u1ee5ng t\u00f3c, vi\u00eam m\u00f3ng; vi\u00eam th\u1eadn k\u1ebd, b\u1ec7nh s\u1ecfi th\u1eadn (c\u00f3 th\u1ec3 ng\u1eebng thu\u1ed1c t\u1ea1m th\u1eddi ho\u1eb7c ng\u1eebng h\u1eb3n, hay g\u1eb7p \u1edf tr\u1ebb em), \u0111\u00e1i kh\u00f3; \u0111\u00e1i ra m\u00e1u, tinh th\u1ec3 ni\u1ec7u, protein ni\u1ec7u, \u0111\u00e1i ra m\u1ee7 (tr\u1ebb em); vi\u00eam gan, t\u0103ng bilirubin huy\u1ebft nh\u1ea5t th\u1eddi; r\u1ed1i lo\u1ea1n m\u00e1u g\u1ed3m gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, thi\u1ebfu m\u00e1u tan huy\u1ebft; lo\u1ea1n d\u01b0\u1ee1ng lipid v\u00e0 t\u00e1c \u0111\u1ed9ng l\u00ean chuy\u1ec3n ho\u00e1 (xem \u1edf tr\u00ean). <\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed Indinavir <\/h2>\n
N\u1ebfu x\u1ea3y ra qu\u00e1 li\u1ec1u c\u1ea5p th\u00ec c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd ng\u01b0\u1eddi b\u1ec7nh. <\/p>\n
\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n Indinavir <\/h2>\n
B\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 15 – 30 o <\/sup> C trong c\u00e1c chai l\u1ecd n\u00fat k\u00edn v\u00e0 c\u00f3 th\u00eam ch\u1ea5t h\u00fat \u1ea9m. <\/p>\n<\/p>\n http:\/\/nidqc.org.vn\/duocthu\/359\/ <\/p>\n","protected":false},"excerpt":{"rendered":"
Indinavir; IDV.Thu\u1ed1c \u1ee9c ch\u1ebf protease.Thu\u1ed1c ch\u1ed1ng retrovirus.Thu\u1ed1c ch\u1ed1ng virus.Thu\u1ed1c tr\u1ecb k\u00fd sinh tr\u00f9ng, ch\u1ed1ng nhi\u1ec5m khu\u1ea9n.<\/p>\n","protected":false},"author":143,"featured_media":10472,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5360,5316,5458,5457,5363,5459,5317],"tags":[],"series":[],"coauthors":[],"acf":[],"yoast_head":"\n
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