{"id":5087,"date":"2018-08-04T08:23:23","date_gmt":"2018-08-04T01:23:23","guid":{"rendered":"https:\/\/yhoccongdong.org\/du-an-khac\/2018\/08\/04\/thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng\/"},"modified":"2024-03-17T03:56:53","modified_gmt":"2024-03-16T20:56:53","slug":"thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/du-an-khac\/thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng\/","title":{"rendered":"Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng v\u00e0 s\u1ee9c kh\u1ecfe r\u0103ng mi\u1ec7ng"},"content":{"rendered":"

Khi ch\u00fang ta ng\u00e0y c\u00e0ng gi\u00e0 \u0111i, x\u01b0\u01a1ng b\u1eaft \u0111\u1ea7u m\u1ea5t d\u1ea7n \u0111\u1ed9 \u0111\u1eadm \u0111\u1eb7c v\u00e0 s\u1ee9c b\u1ec1n, \u0111\u1eb7c bi\u1ec7t l\u00e0 sau 50 tu\u1ed5i. C\u00f3 nhi\u1ec1u y\u1ebfu t\u1ed1 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u1eadt \u0111\u1ed9 x\u01b0\u01a1ng nh\u01b0 ch\u1ebf \u0111\u1ed9 \u0103n, ho\u1ea1t \u0111\u1ed9ng th\u1ec3 l\u1ef1c, ti\u1ec1n s\u1eed gia \u0111\u00ecnh, n\u1ed9i ti\u1ebft t\u1ed1, l\u1ed1i s\u1ed1ng, m\u1ed9t s\u1ed1 t\u00ecnh tr\u1ea1ng kh\u00e1c v\u00e0 thu\u1ed1c s\u1eed d\u1ee5ng. <\/span> <\/span><\/p>\n

Lo\u00e3ng x\u01b0\u01a1ng<\/a> hay x\u1ed1p x\u01b0\u01a1ng l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd l\u00e0m x\u01b0\u01a1ng y\u1ebfu \u0111i v\u00e0 d\u1ec5 g\u00e3y<\/a>, \u0111\u1eb7c bi\u1ec7t x\u01b0\u01a1ng h\u00f4ng, c\u1ed9t s\u1ed1ng, c\u1ed5 tay. B\u1ec7nh lo\u00e3ng x\u01b0\u01a1ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kho\u1ea3ng 10 tri\u1ec7u ng\u01b0\u1eddi M\u1ef9, trong \u0111\u00f3 8 tri\u1ec7u l\u00e0 n\u1eef gi\u1edbi. C\u0103n b\u1ec7nh n\u00e0y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1eef gi\u1edbi nhi\u1ec1u h\u01a1n c\u1ea3 b\u1ec7nh ung th\u01b0, tim m\u1ea1ch v\u00e0 \u0111\u1ed9t qu\u1ef5 k\u00e8m theo. Kho\u1ea3ng 34 tri\u1ec7u ng\u01b0\u1eddi M\u1ef9 b\u1ecb \u201cthi\u1ebfu x\u01b0\u01a1ng\u201d (osteopenia), hay m\u1eadt \u0111\u1ed9 x\u01b0\u01a1ng th\u1ea5p v\u00e0 c\u00f3 nguy c\u01a1 ph\u00e1t tri\u1ec3n th\u00e0nh lo\u00e3ng x\u01b0\u01a1ng. <\/span> <\/span><\/p>\n

\"Thu\u1ed1c <\/span><\/p>\n

Lo\u00e3ng x\u01b0\u01a1ng th\u01b0\u1eddng x\u1ea3y ra \u1edf n\u1eef gi\u1edbi v\u00e0 th\u01b0\u1eddng g\u00e2y g\u00e3y x\u01b0\u01a1ng h\u00f4ng, c\u1ed9t s\u1ed1ng, c\u1ed5 tay <\/em> <\/span> <\/span><\/p>\n

Lo\u00e3ng x\u01b0\u01a1ng v\u00e0 s\u1ef1 g\u00e3y x\u01b0\u01a1ng<\/h2>\n

G\u00e3y x\u01b0\u01a1ng h\u00f4ng v\u00e0 c\u1ed9t s\u1ed1ng l\u00e0m gia t\u0103ng t\u1ef7 l\u1ec7 t\u1eed vong. Theo hi\u1ec7p h\u1ed9i qu\u1ed1c gia v\u1ec1 lo\u00e3ng x\u01b0\u01a1ng (National Osteoporosis Foundation) kho\u1ea3ng \u00bd n\u1eef gi\u1edbi, \u00bc nam gi\u1edbi tr\u00ean 50 tu\u1ed5i b\u1ecb g\u00e3y x\u01b0\u01a1ng l\u00e0 h\u1eadu qu\u1ea3 c\u1ee7a lo\u00e3ng x\u01b0\u01a1ng. C\u0103n b\u1ec7nh n\u00e0y l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y h\u01a1n 2 tri\u1ec7u v\u1ebft g\u00e3y m\u1ed7i n\u0103m v\u00e0 g\u00e2y ra c\u00e1c v\u1ea5n \u0111\u1ec1 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng. Nhi\u1ec1u ng\u01b0\u1eddi kh\u00f4ng c\u00f3 th\u1ec3 h\u1ed3i ph\u1ee5c l\u1ea1i ho\u00e0n to\u00e0n. <\/span> <\/span><\/p>\n

Ng\u0103n ng\u1eeba g\u00e3y x\u01b0\u01a1ng<\/h2>\n

\u0110\u1ec3 ng\u0103n ng\u1eeba t\u00ecnh tr\u1ea1ng g\u00e3y x\u01b0\u01a1ng, nhi\u1ec1u ng\u01b0\u1eddi v\u1edbi m\u1eadt \u0111\u1ed9 x\u01b0\u01a1ng th\u1ea5p hay lo\u00e3ng x\u01b0\u01a1ng \u0111\u00e3 s\u1eed d\u1ee5ng m\u1ed9t trong nh\u1eefng lo\u1ea1i thu\u1ed1c c\u1ee7a nh\u00f3m thu\u1ed1c Bisphosphonates nh\u01b0 alendronate (Fosamax, Merck&Co, Whitehouse Station, NJ) (c\u00f3 t\u00e1c d\u1ee5ng nh\u01b0 nh\u01b0 m\u1ed9t lo\u1ea1i thu\u1ed1c generic), ibandronate (Boniva, Genentech, South San Francisco, Calif), risedronate (Actonel v\u00e0 Atelvia, Warner Chilcott, Dublin) v\u00e0 zoledronic acid (Reclast, Novartis Pharmaceuticals, East Hanover, N.J.). M\u1ed9t lo\u1ea1i thu\u1ed1c m\u1edbi ho\u1ea1t \u0111\u1ed9ng nh\u01b0 Bisphosphonates<\/a> l\u00e0 Denosumab (Prolia, Amgen, Thousand Oaks, California). <\/span><\/span><\/p>\n

C\u00e1c nghi\u00ean c\u1ee9u ch\u1ec9 ra r\u1eb1ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng l\u00e0m gi\u1ea3m nguy c\u01a1 g\u00e3y x\u01b0\u01a1ng b\u1eb1ng c\u00e1ch gi\u1ea3m qu\u00e1 tr\u00ecnh h\u1ee7y x\u01b0\u01a1ng<\/strong> v\u00e0 t\u0103ng m\u1eadt \u0111\u1ed9 x\u01b0\u01a1ng<\/strong>. M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o \u01b0\u1edbc t\u00ednh r\u1eb1ng c\u00e1c lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng l\u00e0m gi\u1ea3m 40% – 50% nguy c\u01a1 g\u00e3y x\u01b0\u01a1ng h\u00f4ng \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ecb lo\u00e3ng x\u01b0\u01a1ng, ng\u0103n ch\u1eb7n g\u1ea7n 100.000 v\u1ebft \u00a0g\u00e3y x\u01b0\u01a1ng h\u00f4ng v\u00e0 nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p t\u1eed vong li\u00ean quan \u0111\u1ebfn g\u00e3y x\u01b0\u01a1ng m\u1ed7i n\u0103m.<\/span><\/span><\/p>\n

Xem th\u00eam b\u00e0i vi\u1ebft\u00a0\u0110i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng<\/a>\u00a0c\u1ee7a\u00a0TS.BS. Hu\u1ef3nh Kim Hi\u1ec7u<\/a><\/strong><\/em><\/pre>\n
Ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m<\/h2>\n
  M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o ghi nh\u1eadn c\u00f3 t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m (osteonecrosis of the jaw \u2013 ONJ) \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng<\/a>. <\/span> <\/span><\/p>\n
  Ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m tuy hi\u1ebfm nh\u01b0ng nghi\u00eam tr\u1ecdng v\u00ec g\u00e2y ra s\u1ef1 t\u1ed5n th\u01b0\u01a1ng tr\u1ea7m tr\u1ecdng cho x\u01b0\u01a1ng h\u00e0m. Kho\u1ea3ng 94% b\u1ec7nh nh\u00e2n ung th\u01b0 \u0111\u00e3 t\u1eebng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ho\u1eb7c \u0111ang \u0111i\u1ec1u tr\u1ecb li\u1ec1u cao v\u00e0 l\u1eb7p l\u1ea1i b\u1eb1ng \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch v\u1edbi thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng c\u00f3 t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m. Kho\u1ea3ng 6% b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng li\u1ec1u th\u1ea5p trong \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng c\u00f3 ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m. <\/em><\/span> <\/span><\/p>\n
  Nguy c\u01a1 ph\u00e1t tri\u1ec3n ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng Bisphosphonates v\u00e0 Denosumab. N\u1ebfu b\u1ea1n s\u1eed d\u1ee5ng m\u1ed9t trong c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng, b\u1ea1n c\u00f3 kh\u1ea3 n\u0103ng ph\u00e1t tri\u1ec3n ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m. Tuy nhi\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u cho r\u1eb1ng kh\u1ea3 n\u0103ng n\u00e0y d\u01b0\u1eddng nh\u01b0 l\u00e0 r\u1ea5t nh\u1ecf<\/strong>. <\/span> <\/span><\/p>\n
  H\u00e3y n\u00f3i v\u1edbi nha s\u0129 c\u1ee7a b\u1ea1n n\u1ebfu b\u1ea1n \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c Bisphosphonate ho\u1eb7c Denosumab. Nha s\u0129 s\u1ebd h\u01b0\u1edbng d\u1eabn c\u00e1ch th\u1ef1c h\u00e0nh v\u1ec7 sinh r\u0103ng mi\u1ec7ng t\u1ed1t<\/a>, c\u0169ng nh\u01b0 theo d\u00f5i s\u1ee9c kh\u1ecfe r\u0103ng mi\u1ec7ng c\u1ee7a b\u1ea1n trong khi b\u1ea1n \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c n\u00e0y. <\/span> <\/span><\/p>\n
H\u00e3y n\u00f3i chuy\u1ec7n v\u1edbi b\u00e1c s\u0129<\/h2>\n
  Hi\u1ec7p h\u1ed9i Nha Khoa Hoa K\u1ef3 tin r\u1eb1ng b\u00e1c s\u0129 c\u1ee7a b\u1ea1n v\u00e0\/ho\u1eb7c nh\u00e0 cung c\u1ea5p ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe l\u00e0 ngu\u1ed3n th\u00f4ng tin t\u1ed1t nh\u1ea5t v\u1ec1 nhu c\u1ea7u s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng c\u1ee7a b\u1ea1n. B\u1ea1n kh\u00f4ng n\u00ean ng\u1eebng s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y m\u00e0 kh\u00f4ng n\u00f3i chuy\u1ec7n v\u1edbi b\u00e1c s\u0129. N\u1ebfu b\u1ea1n b\u1ecb lo\u00e3ng x\u01b0\u01a1ng ho\u1eb7c c\u00f3 nguy c\u01a1 cao g\u00e3y x\u01b0\u01a1ng t\u00e1i ph\u00e1t, l\u1ee3i \u00edch c\u1ee7a nh\u1eefng lo\u1ea1i thu\u1ed1c n\u00e0y l\u1edbn h\u01a1n r\u1ea5t nhi\u1ec1u so v\u1edbi nh\u1eefng r\u1ee7i ro th\u1ea5p c\u1ee7a s\u1ef1 ph\u00e1t tri\u1ec3n ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m<\/em>. Kh\u00f4ng c\u00f3 bi\u1ec7n ph\u00e1p ng\u0103n ng\u1eeba ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m. Tuy nhi\u00ean, th\u01b0\u1eddng xuy\u00ean kh\u00e1m r\u0103ng v\u00e0 th\u1ef1c h\u00e0nh v\u1ec7 sinh r\u0103ng mi\u1ec7ng t\u1ed1t c\u00f3 th\u1ec3 l\u00e0 c\u00e1ch t\u1ed1t nh\u1ea5t \u0111\u1ec3 gi\u1ea3m nguy c\u01a1. <\/span> <\/span><\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
  http:\/\/www.ada.org\/sections\/scienceAndResearch\/pdfs\/forthedentalpatient_nov2011.pdf <\/a> <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"
M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o ghi nh\u1eadn c\u00f3 t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m (osteonecrosis of the jaw \u2013 ONJ) \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng.<\/p>\n
Ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m tuy hi\u1ebfm nh\u01b0ng nghi\u00eam tr\u1ecdng v\u00ec g\u00e2y ra s\u1ef1 t\u1ed5n th\u01b0\u01a1ng tr\u1ea7m tr\u1ecdng cho x\u01b0\u01a1ng h\u00e0m. Kho\u1ea3ng 94% b\u1ec7nh nh\u00e2n ung th\u01b0 \u0111\u00e3 t\u1eebng \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ho\u1eb7c \u0111ang \u0111i\u1ec1u tr\u1ecb li\u1ec1u cao v\u00e0 l\u1eb7p l\u1ea1i b\u1eb1ng \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch v\u1edbi thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng c\u00f3 t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m. Kho\u1ea3ng 6% b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng li\u1ec1u th\u1ea5p trong \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng c\u00f3 ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m.<\/p>\n","protected":false},"author":56,"featured_media":5088,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5148,5241,3816,5242],"tags":[4163,4164,3772],"series":[1510],"coauthors":[1608],"acf":[],"yoast_head":"\nThu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng v\u00e0 s\u1ee9c kh\u1ecfe r\u0103ng mi\u1ec7ng - Y H\u1ecdc C\u1ed9ng \u0110\u1ed3ng<\/title>\n<meta name=\"description\" content=\"M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o ghi nh\u1eadn t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m do \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng, tuy nhi\u00ean l\u1ee3i \u00edch t\u1eeb vi\u1ec7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ng\u0103n ch\u1eb7n g\u00e3y x\u01b0\u01a1ng v\u01b0\u1ee3t xa nguy c\u01a1 ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/du-an-khac\/thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng v\u00e0 s\u1ee9c kh\u1ecfe r\u0103ng mi\u1ec7ng - Y H\u1ecdc C\u1ed9ng \u0110\u1ed3ng\" \/>\n<meta property=\"og:description\" content=\"M\u1ed9t s\u1ed1 b\u00e1o c\u00e1o ghi nh\u1eadn t\u00ecnh tr\u1ea1ng ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m do \u0111i\u1ec1u tr\u1ecb lo\u00e3ng x\u01b0\u01a1ng, tuy nhi\u00ean l\u1ee3i \u00edch t\u1eeb vi\u1ec7c \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ng\u0103n ch\u1eb7n g\u00e3y x\u01b0\u01a1ng v\u01b0\u1ee3t xa nguy c\u01a1 ho\u1ea1i t\u1eed x\u01b0\u01a1ng h\u00e0m.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/yhoccongdong.com\/du-an-khac\/thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng\/\" \/>\n<meta property=\"og:site_name\" content=\"D\u1ef1 \u00e1n kh\u00e1c\" \/>\n<meta property=\"article:author\" content=\"http:\/\/facebook.com\/ngothanhtam1982\" \/>\n<meta property=\"article:published_time\" content=\"2018-08-04T01:23:23+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-16T20:56:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/yhoccongdong.com\/du-an-khac\/wp-content\/uploads\/sites\/6\/2013\/11\/thuoc-dieu-tri-loang-xuong-va-suc-khoe-rang-mieng.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"664\" \/>\n\t<meta property=\"og:image:height\" content=\"330\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ths.BS. 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