{"id":4218,"date":"2018-09-28T13:38:35","date_gmt":"2018-09-28T06:38:35","guid":{"rendered":"https:\/\/yhoccongdong.org\/du-an-khoa-nhi\/2018\/09\/28\/ung-dung-cua-viec-bo-sung-kem-trong-lam-sang-mot-so-benh-thuong-gap\/"},"modified":"2024-03-04T13:50:55","modified_gmt":"2024-03-04T06:50:55","slug":"ung-dung-cua-viec-bo-sung-kem-trong-lam-sang-mot-so-benh-thuong-gap","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/nhi-khoa\/ung-dung-cua-viec-bo-sung-kem-trong-lam-sang-mot-so-benh-thuong-gap\/","title":{"rendered":"\u1ee8ng d\u1ee5ng c\u1ee7a vi\u1ec7c b\u1ed5 sung k\u1ebdm trong l\u00e2m s\u00e0ng m\u1ed9t s\u1ed1 b\u1ec7nh th\u01b0\u1eddng g\u1eb7p"},"content":{"rendered":"<h2>B\u1ed5 sung k\u1ebdm trong ph\u00f2ng ng\u1eeba ti\u00eau ch\u1ea3y v\u00e0 vi\u00eam ph\u1ed5i<\/h2>\n<p>Nhi\u1ec1u nghi\u00ean c\u1ee9u t\u1ea1i c\u00e1c n\u01b0\u1edbc \u0111ang ph\u00e1t tri\u1ec3n ch\u1ec9 ra r\u1eb1ng vi\u1ec7c b\u1ed5 sung th\u01b0\u1eddng quy k\u1ebdm \u0111\u01b0\u1eddng u\u1ed1ng l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c t\u1ea7n su\u1ea5t m\u1eafc b\u1ec7nh ti\u00eau ch\u1ea3y, t\u1eed vong li\u00ean quan \u0111\u1ebfn ti\u00eau ch\u1ea3y v\u00e0 vi\u00eam ph\u1ed5i [1].<\/p>\n<p>Trong m\u1ed9t ph\u00e2n t\u00edch meta, vi\u1ec7c b\u1ed5 sung k\u1ebdm trong v\u00f2ng 3 th\u00e1ng ho\u1eb7c h\u01a1n cho tr\u1ebb em t\u1eeb 2 tu\u1ed5i l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c s\u1ed1 \u0111\u1ee3t ti\u00eau ch\u1ea3y, vi\u00eam h\u00f4 h\u1ea5p, ti\u00eau ch\u1ea3y n\u1eb7ng ho\u1eb7c l\u1ef5, ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i, nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p d\u01b0\u1edbi v\u00e0 vi\u00eam ph\u1ed5i [2].<\/p>\n<p>Hai ph\u00e2n t\u00edch meta bao g\u1ed3m nhi\u1ec1u th\u1eed nghi\u1ec7m gi\u1ed1ng nhau c\u0169ng th\u1ea5y r\u1eb1ng b\u1ed5 sung k\u1ebdm cho tr\u1ebb t\u1eeb 2-5 tu\u1ed5i \u1edf c\u00e1c n\u01b0\u1edbc \u0111ang ph\u00e1t tri\u1ec3n l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c t\u1ea7n su\u1ea5t vi\u00eam ph\u1ed5i kho\u1ea3ng 20% v\u00e0 ti\u00eau ch\u1ea3y 13%. Li\u1ec1u k\u1ebdm d\u00f9ng trong nghi\u00ean c\u1ee9u n\u00e0y dao \u0111\u1ed9ng t\u1eeb 15- 140 mg k\u1ebdm nguy\u00ean t\u1ed1 \/ tu\u1ea7n [3].<\/p>\n<h2>K\u1ebdm trong \u0111i\u1ec1u tr\u1ecb ti\u00eau ch\u1ea3y c\u1ea5p<\/h2>\n<ul>\n<li>Trong 1 th\u1eed nghi\u1ec7m v\u1edbi 937 tr\u1ebb em b\u1ecb ti\u00eau ch\u1ea3y c\u1ea5p \u1edf \u1ea4n \u0110\u1ed9, cho th\u1ea5y b\u1ed5 sung 20 mg k\u1ebdm m\u1ed7i ng\u00e0y l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c th\u1eddi gian ti\u00eau ch\u1ea3y l\u00e0 23% gi\u1ea3m l\u01b0\u1ee3ng n\u01b0\u1edbc trong ph\u00e2n l\u00e0 39%.<\/li>\n<li>WHO khuy\u1ebfn c\u00e1o 10 mg k\u1ebdm nguy\u00ean t\u1ed1\/ ng\u00e0y v\u1edbi tr\u1ebb &lt;6 th\u00e1ng v\u00e0 20mg\/ ng\u00e0y v\u1edbi tr\u1ebb &lt;6 th\u00e1ng \u1edf c\u00e1c n\u01b0\u1edbc \u0111ang ph\u00e1t tri\u1ec3n b\u1ecb ti\u00eau ch\u1ea3y c\u1ea5p, th\u1eddi gian 10 \u2013 14 ng\u00e0y.<\/li>\n<\/ul>\n<h2>K\u1ebdm trong \u0111i\u1ec1u tr\u1ecb ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i<\/h2>\n<ul>\n<li>T\u1ed5 Ch\u1ee9c y t\u1ebf th\u1ebf gi\u1edbi \u0111\u1ecbnh ngh\u0129a ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i l\u00e0 l\u00e0 \u0111\u1ee3t ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i qu\u00e1 14 ng\u00e0y, ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i c\u00f3 li\u00ean quan t\u1edbi t\u1ef7 l\u1ec7 t\u1eed vong cao v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 t\u0103ng tr\u01b0\u1edfng m\u1ea1nh h\u01a1n l\u00e0 ti\u00eau ch\u1ea3y c\u1ea5p..<\/li>\n<li>Nh\u1eefng th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean c\u00f3 ki\u1ec3m so\u00e1t \u1edf tr\u1ebb em b\u1ecb ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i \u0111\u1ec1u ch\u1ec9 ra r\u1eb1ng, vi\u1ec7c b\u1ed5 sung k\u1ebdm s\u1ebd l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c \u0111\u1ed9 n\u1eb7ng v\u00e0 th\u1eddi gian c\u1ee7a c\u1ea3 ti\u00eau ch\u1ea3y k\u00e9o d\u00e0i v\u00e0 ti\u00eau ch\u1ea3y c\u1ea5p. D\u1ef1a tr\u00ean c\u00e1c d\u1eef li\u1ec7u \u0111\u00f3 WHO khuy\u1ebfn ngh\u1ecb b\u1ed5 sung k\u1ebdm cho tr\u1ebb em b\u1ecb ti\u00eau ch\u1ea3y \u1edf c\u00e1c n\u01b0\u1edbc \u0111ang ph\u00e1t tri\u1ec3n v\u1edbi li\u1ec1u 10 mg\/ ng\u00e0y cho tr\u1ebb d\u01b0\u1edbi 6 th\u00e1ng v\u00e0 20 mg\/ ng\u00e0y v\u1edbi tr\u1ebb tr\u00ean 6 th\u00e1ng.<\/li>\n<\/ul>\n<h2>K\u1ebdm trong \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 c\u00e1c nhi\u1ec5m tr\u00f9ng do vi khu\u1ea9n<\/h2>\n<ul>\n<li>B\u1ed5 sung k\u1ebdm xu\u1ea5t hi\u1ec7n l\u1ee3i \u00edch c\u1ed9ng th\u00eam c\u00f9ng v\u1edbi li\u1ec7u ph\u00e1p kh\u00e1ng sinh trong \u0111i\u1ec1u tr\u1ecb c\u00e1c nhi\u1ec5m tr\u00f9ng n\u1eb7ng \u1edf tr\u1ebb nh\u1ecf.<\/li>\n<li>\u0110i\u1ec1u n\u00e0y \u0111\u01b0\u1ee3c ch\u1ec9 ra trong 1 th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean l\u1edbn tr\u00ean 700 tr\u1ebb em t\u1eeb 7 ng\u00e0y tu\u1ed5i \u2013 120 ng\u00e0y tu\u1ed5i t\u1ea1i \u1ea4n \u0110\u1ed9 v\u1edbi c\u00e1c b\u1ec7nh nhi\u1ec5m tr\u00f9ng n\u1eb7ng nh\u01b0: Vi\u00eam ph\u1ed5i, nhi\u1ec5m tr\u00f9ng huy\u1ebft v\u00e0 ti\u00eau ch\u1ea3y. T\u1ea5t c\u1ea3 nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y \u0111\u1ec1u \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng kh\u00e1ng sinh theo Protocol chu\u1ea9n. Nh\u1eefng tr\u1ebb m\u00e0 \u0111\u01b0\u1ee3c cho k\u1ebdm v\u1edbi li\u1ec1u 5mg x 2 l\u1ea7n\/ ng\u00e0y th\u00ec gi\u1ea3m t\u1ec9 l\u1ec7 th\u1ea5t b\u1ea1i \u0111i\u1ec1u tr\u1ecb so v\u1edbi nh\u00f3m d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c (10% so v\u1edbi 17%).<\/li>\n<\/ul>\n<h2>K\u1ebdm trong t\u0103ng tr\u01b0\u1edfng, \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng s\u1ed1t r\u00e9t<\/h2>\n<p>B\u1eb1ng ch\u1ee9ng y\u1ebfu, c\u1ea7n th\u00eam nghi\u00ean c\u1ee9<\/p>\n<h2>K\u1ebdm trong b\u1ec7nh c\u1ea3m l\u1ea1nh<\/h2>\n<ul>\n<li>Kh\u00f4ng khuy\u1ebfn c\u00e1o vi\u1ec7c s\u1eed d\u1ee5ng k\u1ebdm trong \u0111i\u1ec1u tr\u1ecb c\u1ea3m l\u1ea1nh th\u01b0\u1eddng \u1edf tr\u1ebb em. Hi\u1ec7u qu\u1ea3 c\u1ee7a k\u1ebdm trong vi\u1ec7c l\u00e0m gi\u1ea3m th\u1eddi gian hay \u0111\u1ed9 n\u1eb7ng c\u1ee7a c\u00e1c tri\u1ec7u ch\u1ee9ng \u1edf tr\u1ebb em l\u00e0 kh\u00f4ng r\u00f5 r\u00e0ng, v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a n\u00f3 l\u1ea1i kh\u00e1 ph\u1ed5 bi\u1ebfn [2].<\/li>\n<li>M\u1eb7c d\u00f9 c\u00f3 1 v\u00e0i th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean c\u00f3 h\u1ec7 th\u1ed1ng g\u1ee3i \u00fd r\u1eb1ng k\u1ebdm c\u00f3 th\u1ec3 r\u00fat ng\u1eafn th\u1eddi gian c\u1ee7a c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0ng l\u1ea1i c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t \u0111\u00e1ng k\u1ec3 gi\u1eefa c\u00e1c th\u1eed nghi\u1ec7m n\u00e0y [2,3]. V\u00e0o n\u0103m 2012 m\u1ed9t t\u1ed5ng quan h\u1ec7 th\u1ed1ng v\u00e0 ph\u00e2n t\u00edch t\u1eeb 8 th\u1eed nghi\u1ec7m (c\u00f3 934 ng\u01b0\u1eddi tham gia, trong \u0111\u00f3 c\u00f3 371 ng\u01b0\u1eddi l\u1edbn v\u00e0 563 tr\u1ebb em), k\u1ebdm \u0111\u00e3 l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c th\u1eddi gian bi\u1ec3u hi\u1ec7n tri\u1ec7u ch\u1ee9ng (1.65 ng\u00e0y) [ 2].<\/li>\n<li>Khi ph\u00e2n t\u00edch trong t\u1eebng nh\u00f3m th\u00ec th\u1ea5y k\u1ebdm l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c th\u1eddi gian bi\u1ec3u hi\u1ec7n tri\u1ec7u ch\u1ee9ng \u1edf ng\u01b0\u1eddi l\u1edbn (trung b\u00ecnh 2.63 ng\u00e0y) nh\u01b0ng \u1edf nh\u00f3m tr\u1ebb em th\u00ec kh\u00f4ng (ch\u1ec9 kh\u00e1c bi\u1ec7t 0.26 ng\u00e0y).<\/li>\n<li>T\u00e1c d\u1ee5ng c\u1ee7a k\u1ebdm c\u00f2n thay \u0111\u1ed5i t\u00f9y theo c\u00f4ng th\u1ee9c c\u1ee7a k\u1ebdm v\u00e0 li\u1ec1u c\u1ee7a ion k\u1ebdm (k\u1ebdm acetate th\u00ec c\u00f3 hi\u1ec7u qu\u1ea3, k\u1ebdm gluconate v\u00e0 k\u1ebdm sulfate th\u00ec kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3. Li\u1ec1u l\u00e0 tr\u00ean 75 mg th\u00ec hi\u1ec7u qu\u1ea3 h\u01a1n li\u1ec1u th\u1ea5p h\u01a1n).<\/li>\n<li>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 bao g\u1ed3m: v\u1ecb kh\u00f3 ch\u1ecbu, bu\u1ed3n n\u00f4n l\u00e0 ph\u1ed5 bi\u1ebfn, g\u00f3p ph\u1ea7n l\u00e0m k\u1ebdm tr\u1edf n\u00ean kh\u00f3 s\u1eed d\u1ee5ng \u1edf tr\u1ebb em<\/li>\n<\/ul>\n<h2>Ng\u1ed9 \u0111\u1ed9c k\u1ebdm<\/h2>\n<p>\u00cdt khi x\u1ea3y ra ng\u1ed9 \u0111\u1ed9c k\u1ebdm, d\u00f9ng v\u1edbi li\u1ec1u g\u1ea5p 10 l\u1ea7n li\u1ec1u khuy\u1ebfn c\u00e1o m\u1ed7i ng\u00e0y c\u0169ng kh\u00f4ng g\u00e2y tri\u1ec7u ch\u1ee9ng. S\u1ef1 h\u1ea5p thu c\u1ee7a \u0111\u1ed3ng s\u1ebd b\u1ecb gi\u1ea3m do k\u1ebdm, do \u0111\u00f3 b\u1ed5 sung k\u1ebdm li\u1ec1u cao k\u00e9o d\u00e0i s\u1ebd d\u1eabn t\u1edbi thi\u1ebfu h\u1ee5t \u0111\u1ed3ng<\/p>\n<p>U\u1ed1ng 1 li\u1ec1u 1-2 gam k\u1ebdm sulfate g\u00e2y bu\u1ed3n n\u00f4n, n\u00f4n li\u00ean quan t\u1edbi t\u00ecnh tr\u1ea1ng k\u00edch \u1ee9ng d\u1ea1 d\u00e0y ru\u1ed9t. U\u1ed1ng 1 li\u1ec1u l\u1edbn k\u1ebdm c\u0169ng c\u00f3 th\u1ec3 g\u00e2y suy th\u1eadn c\u1ea5p do ho\u1ea1i t\u1eed \u1ed1ng th\u1eadn v\u00e0 vi\u00eam th\u1eadn k\u1ebd<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Medline \u00ae Abstracts for References 58-66 of &#8220;Zinc deficiency and supplementation in children and adolescents&#8221;<\/li>\n<li>Medline \u00ae Abstract for Reference 63 of &#8220;Zinc deficiency and supplementation in children and adolescents&#8221;<\/li>\n<li>Medline \u00ae Abstracts for References 64,67 of &#8220;Zinc deficiency and supplementation in children and adolescents&#8221;<\/li>\n<li><a href=\"https:\/\/www.facebook.com\/diendannhikhoa\/posts\/684948695035987?__tn__=K-R\" target=\"_blank\" rel=\"noopener\">https:\/\/www.facebook.com\/diendannhikhoa\/posts\/684948695035987?__tn__=K-R<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>B\u1ed5 sung k\u1ebdm th\u01b0\u1eddng quy \u0111\u01b0\u1eddng u\u1ed1ng l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c t\u1ea7n su\u1ea5t m\u1eafc b\u1ec7nh ti\u00eau ch\u1ea3y, t\u1eed vong li\u00ean quan \u0111\u1ebfn ti\u00eau ch\u1ea3y v\u00e0 vi\u00eam ph\u1ed5<\/p>\n","protected":false},"author":14,"featured_media":4220,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6104],"tags":[5727,5728],"series":[3454],"coauthors":[2652],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u1ee8ng d\u1ee5ng c\u1ee7a vi\u1ec7c b\u1ed5 sung k\u1ebdm trong l\u00e2m s\u00e0ng m\u1ed9t s\u1ed1 b\u1ec7nh th\u01b0\u1eddng g\u1eb7p - D\u1ef1 \u00e1n Nhi Khoa<\/title>\n<meta name=\"description\" content=\"B\u1ed5 sung k\u1ebdm th\u01b0\u1eddng quy \u0111\u01b0\u1eddng u\u1ed1ng l\u00e0m gi\u1ea3m \u0111\u01b0\u1ee3c t\u1ea7n su\u1ea5t m\u1eafc b\u1ec7nh ti\u00eau ch\u1ea3y, t\u1eed vong 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