{"id":12120,"date":"2018-07-12T02:56:44","date_gmt":"2018-07-11T19:56:44","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/an-toan-benh-nhan-trong-thu-nghiem-lam-sang\/"},"modified":"2018-07-12T02:56:44","modified_gmt":"2018-07-11T19:56:44","slug":"an-toan-benh-nhan-trong-thu-nghiem-lam-sang","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/an-toan-benh-nhan-trong-thu-nghiem-lam-sang\/","title":{"rendered":"An to\u00e0n b\u1ec7nh nh\u00e2n trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng"},"content":{"rendered":"<p>An to\u00e0n b\u1ec7nh nh\u00e2n l\u00e0 v\u1ea5n \u0111\u1ec1 \u0111\u01b0\u1ee3c quan t\u00e2m h\u00e0ng \u0111\u1ea7u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. \u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao m\u1ed7i m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u1ec1u ph\u1ea3i tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t c\u00e1c quy tr\u00ecnh ki\u1ec3m tra, trong \u0111\u00f3 c\u00f3 v\u1ea5n \u0111\u1ec1 an to\u00e0n c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n<h2>Ai l\u00e0 ng\u01b0\u1eddi \u0111\u1ec1 ra c\u00e1c quy t\u1eafc trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng?<\/h2>\n<p>C\u00e1c b\u00e1c s\u0129 v\u00e0 nh\u00e2n vi\u00ean y t\u1ebf ph\u1ea3i tu\u00e2n th\u1ee7 theo c\u00e1c quy t\u1eafc \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp b\u1edfi c\u00e1c nh\u00f3m chuy\u00ean gia. C\u00e1c quy t\u1eafc n\u00e0y \u0111\u01b0\u1ee3c th\u00e0nh l\u1eadp nh\u1eb1m m\u1ee5c \u0111\u00edch gi\u1eef an to\u00e0n t\u1ed1i \u0111a cho b\u1ec7nh nh\u00e2n v\u00e0 cho c\u00e1c t\u00ecnh nguy\u1ec7n vi\u00ean kh\u00e1c trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Sau \u0111\u00e2y l\u00e0 ba nh\u00f3m chuy\u00ean gia ch\u1ecbu tr\u00e1ch nhi\u1ec7m \u0111\u1ec1 ra c\u00e1c quy t\u1eafc cho c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh \u1edf Hoa K\u1ef3<\/p>\n<ul>\n<li>H\u1ed9i \u0111\u1ed3ng \u0111\u1ea1o \u0111\u1ee9c t\u1ea1i c\u01a1 quan (n\u01b0\u1edbc ngo\u00e0i th\u01b0\u1eddng g\u1ecdi l\u00e0 Institional Review Board, IRB). \u0110\u00e2y l\u00e0 \u1ee6y ban g\u1ed3m c\u00e1c chuy\u00ean gia c\u00f3 nhi\u1ec7m v\u1ee5 b\u1ea3o \u0111\u1ea3m c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u00fang \u0111\u1eafn, an to\u00e0n v\u00e0 c\u00f4ng b\u1eb1ng nh\u1eb1m m\u1ee5c \u0111\u00edch b\u1ea3o v\u1ec7 nh\u00e2n quy\u1ec1n v\u00e0 ph\u00fac l\u1ee3i c\u1ee7a c\u00e1c t\u00ecnh nguy\u1ec7n vi\u00ean. H\u1ed9i \u0111\u1ed3ng n\u00e0y ph\u1ea3i ph\u00ea chu\u1ea9n v\u00e0 theo d\u00f5i m\u1ecdi th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng c\u00f3 li\u00ean quan \u0111\u1ebfn con ng\u01b0\u1eddi. Nh\u00f3m ph\u1ee5 tr\u00e1ch th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ph\u1ea3i cung c\u1ea5p \u0111\u1ea7y \u0111\u1ee7 th\u00f4ng tin v\u00e0 \u0111\u01b0\u1ee3c H\u1ed9i \u0111\u1ed3ng n\u00e0y th\u00f4ng qua th\u00ec m\u1edbi \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi.<\/li>\n<li>T\u1ed5 ch\u1ee9c ch\u00ednh ph\u1ee7 (Goverment organization). T\u1ea1i Hoa K\u1ef3, C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m (The Food and Drug Administration, FDA) \u0111\u1ec1 ra c\u00e1c quy t\u1eafc cho c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Vi\u1ec7n Y t\u1ebf qu\u1ed1c gia (The National Institutes of Health) ch\u1ecbu tr\u00e1ch nhi\u1ec7m theo d\u00f5i c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng.<\/li>\n<li>Ban ki\u1ec3m so\u00e1t d\u1eef li\u1ec7u v\u00e0 an to\u00e0n (Data and Safety Monitoring Board, DSMB). Ban n\u00e0y bao g\u1ed3m nhi\u1ec1u chuy\u00ean gia gi\u00fap ki\u1ec3m so\u00e1t qu\u00e1 tr\u00ecnh th\u1ef1c thi th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. DSMB \u0111\u1ea3m b\u1ea3o an to\u00e0n cho c\u00e1c t\u00ecnh nguy\u1ec7n vi\u00ean, c\u0169ng nh\u01b0 gi\u00fap c\u00e1c b\u00e1c s\u0129 thu \u0111\u01b0\u1ee3c c\u00e1c th\u00f4ng tin c\u00f3 gi\u00e1 tr\u1ecb t\u1eeb th\u1eed nghi\u1ec7m. Ban n\u00e0y c\u00f2n b\u00e1o cho t\u1ed5 ch\u1ee9c ch\u1ecbu tr\u00e1ch nhi\u1ec7m ti\u1ebfn h\u00e0nh th\u1eed nghi\u1ec7m v\u1ec1 vi\u1ec7c c\u00f3 n\u00ean thay \u0111\u1ed5i, ch\u1ea5m d\u1ee9t ho\u1eb7c ti\u1ebfp t\u1ee5c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng hay kh\u00f4ng.<\/li>\n<\/ul>\n<h2>Tr\u01b0\u1edbc khi tham gia th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng, t\u00f4i (b\u1ec7nh nh\u00e2n) th\u01b0\u1eddng \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n<p>Nh\u00f3m nghi\u00ean c\u1ee9u s\u1ebd t\u01b0 v\u1ea5n \u0111\u1ec3 b\u1ea1n hi\u1ec3u r\u00f5 v\u1ec1 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u01b0\u1edbc khi b\u1ea1n quy\u1ebft \u0111\u1ecbnh c\u00f3 tham gia hay kh\u00f4ng. H\u1ecd s\u1ebd \u0111\u01b0a cho b\u1ea1n m\u1ed9t v\u0103n b\u1ea3n g\u1ecdi l\u00e0 Phi\u1ebfu ch\u1ea5p nh\u1eadn tham gia nghi\u00ean c\u1ee9u sau khi \u0111\u01b0\u1ee3c gi\u1ea3i th\u00edch \u0111\u1ea7y \u0111\u1ee7 (Informed Consent) trong \u0111\u00f3 c\u00e1c v\u1ea5n \u0111\u1ec1 li\u00ean quan \u0111\u1ebfn nghi\u00ean c\u1ee9u s\u1ebd \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea v\u00e0 gi\u1ea3i th\u00edch r\u00f5 r\u00e0ng: c\u00e1c l\u1ef1a ch\u1ecdn d\u00e0nh cho b\u1ea1n, c\u00e1c nguy c\u01a1 v\u00e0 l\u1ee3i \u00edch m\u00e0 b\u1ea1n nh\u1eadn \u0111\u01b0\u1ee3c khi tham gia nghi\u00ean c\u1ee9u. B\u00e1c s\u0129 v\u00e0 c\u00e1c th\u00e0nh vi\u00ean trong nh\u00f3m nghi\u00ean c\u1ee9u s\u1ebd tr\u1ef1c ti\u1ebfp t\u01b0 v\u1ea5n v\u00e0 tr\u1ea3 l\u1eddi c\u00e1c th\u1eafc m\u1eafc c\u1ee7a b\u1ea1n:<\/p>\n<ul>\n<li>C\u00e1c l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb, bao g\u1ed3m c\u1ea3 quy\u1ebft \u0111\u1ecbnh kh\u00f4ng ti\u1ebfp t\u1ee5c tham gia v\u00e0o nghi\u00ean c\u1ee9u.<\/li>\n<li>Th\u1eed nghi\u1ec7m \u0111i\u1ec1u tr\u1ecb n\u00e0y c\u00f3 g\u00ec kh\u00e1c so v\u1edbi \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n hi\u1ec7n t\u1ea1i v\u00e0 v\u00ec sao c\u00e1c b\u00e1c s\u0129 ph\u1ea3i ti\u1ebfn h\u00e0nh nghi\u00ean c\u1ee9u n\u00e0y.<\/li>\n<li>C\u00e1c nguy c\u01a1 v\u00e0 l\u1ee3i \u00edch c\u1ee7a \u0111i\u1ec1u tr\u1ecb th\u1eed nghi\u1ec7m: ch\u00fang c\u00f3 th\u1ec3 tu\u01a1ng \u0111\u1ed3ng ho\u1eb7c kh\u00e1c so v\u1edbi \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n hi\u1ec7n t\u1ea1i<\/li>\n<li>C\u00e1c vi\u1ec7c b\u1ea1n c\u1ea7n n\u1eafm r\u00f5 khi tham gia nghi\u00ean c\u1ee9u\n<ul>\n<li>S\u1ed1 l\u01b0\u1ee3ng c\u00e1c l\u1ea7n th\u0103m kh\u00e1m v\u00e0 x\u00e9t nghi\u1ec7m<\/li>\n<li>L\u1ecbch tr\u00ecnh \u0111i\u1ec1u tr\u1ecb<\/li>\n<li>Quy\u1ec1n l\u1ee3i \u0111\u01b0\u1ee3c r\u00fat lui kh\u1ecfi nghi\u00ean c\u1ee9u b\u1ea5t c\u1ee9 l\u00fac n\u00e0o<\/li>\n<li>Quy\u1ec1n l\u1ee3i v\u1ec1 kinh t\u1ebf<\/li>\n<li>S\u1ef1 b\u1ea3o \u0111\u1ea3m an to\u00e0n v\u1ec1 th\u00f4ng tin c\u00e1 nh\u00e2n c\u0169ng nh\u01b0 c\u00e1c v\u1ea5n \u0111\u1ec1 ri\u00eang t\u01b0<\/li>\n<li>Th\u00f4ng tin li\u00ean l\u1ea1c v\u1edbi nh\u00f3m nghi\u00ean c\u1ee9u khi c\u00f3 b\u1ea5t c\u1ee9 c\u00e2u h\u1ecfi hay th\u1eafc m\u1eafc n\u00e0o<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>\u0110\u00f4i khi b\u1ea1n c\u0169ng c\u1ea7n th\u00f4ng b\u00e1o cho gia \u0111\u00ecnh ho\u1eb7c b\u1ea1n b\u00e8 v\u1ec1 vi\u1ec7c ch\u1ea5p thu\u1eadn tham gia nghi\u00ean c\u1ee9u c\u1ee7a m\u00ecnh. Khi b\u1ea1n \u0111\u1ed3ng \u00fd tham gia, b\u1ea1n s\u1ebd k\u00ed t\u00ean v\u00e0o bi\u00ean b\u1ea3n ch\u1ea5p thu\u1eadn cho nh\u00f3m nghi\u00ean c\u1ee9u l\u01b0u tr\u1eef th\u00f4ng tin y khoa c\u1ee7a b\u1ea1n<\/p>\n<p>B\u1ea1n v\u1eabn c\u00f3 quy\u1ec1n \u0111\u01b0\u1ee3c \u0111\u1eb7t c\u00e1c c\u00e2u h\u1ecfi sau khi \u0111\u00e3 k\u00fd t\u00ean v\u00e0o Phi\u1ebfu ch\u1ea5p nh\u1eadn tham gia nghi\u00ean c\u1ee9u. C\u00e1c th\u00e0nh vi\u00ean c\u1ee7a nh\u00f3m nghi\u00ean c\u1ee9u s\u1eb5n s\u00e0ng tr\u1ea3 l\u1eddi c\u00e1c th\u1eafc m\u1eafc c\u1ee7a b\u1ea1n, v\u00e0 c\u00e1c th\u00f4ng tin m\u1edbi v\u1ec1 nghi\u00ean c\u1ee9u s\u1ebd \u0111\u01b0\u1ee3c h\u1ecd c\u1eadp nh\u1eadp th\u01b0\u1eddng xuy\u00ean cho b\u1ea1n.<\/p>\n<h2>T\u00f4i c\u00f3 th\u1ec3 ng\u1eebng tham gia v\u00e0o th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng hay kh\u00f4ng?<\/h2>\n<p>Nh\u01b0 \u0111\u00e3 tr\u00ecnh b\u00e0y \u1edf tr\u00ean, b\u1ea1n c\u00f3 quy\u1ec1n ng\u1eebng tham gia v\u00e0o nghi\u00ean c\u1ee9u v\u00e0o B\u1ea4T K\u1ef2 th\u1eddi \u0111i\u1ec3m n\u00e0o v\u00ec l\u00fd do c\u00e1 nh\u00e2n hay s\u1ee9c kh\u1ecfe. B\u1ea1n s\u1ebd v\u1eabn nh\u1eadn \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n hi\u1ec7n t\u1ea1i sau khi ng\u1eebng tham gia v\u00e0o nghi\u00ean c\u1ee9u.<\/p>\n<h2>Chuy\u1ec7n g\u00ec s\u1ebd x\u1ea3y ra n\u1ebfu c\u0103n b\u1ec7nh ung th\u01b0 c\u1ee7a t\u00f4i di\u1ec5n ti\u1ebfn x\u1ea5u?<\/h2>\n<p>Gi\u1ed1ng nh\u01b0 \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n, c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u00f4i khi kh\u00f4ng ch\u1ee9ng t\u1ecf \u0111\u01b0\u1ee3c v\u1ec1 m\u1eb7t l\u1ee3i \u00edch. Khi t\u00ecnh tr\u1ea1ng ung th\u01b0 di\u1ec5n ti\u1ebfn x\u1ea5u, b\u1ea1n c\u00f3 th\u1ec3 l\u1ef1a ch\u1ecdn r\u1eddi b\u1ecf ho\u1eb7c ti\u1ebfp t\u1ee5c tham gia v\u00e0o nghi\u00ean c\u1ee9u. B\u1ea1n c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n hay ng\u01b0ng \u0111i\u1ec1u tr\u1ecb tu\u1ef3 v\u00e0o mong mu\u1ed1n c\u1ee7a b\u1ea1n. Tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh, b\u1ea1n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a nh\u00f3m nghi\u00ean c\u1ee9u, c\u1ee7a gia \u0111\u00ecnh v\u00e0 b\u1ea1n b\u00e8.<\/p>\n<h2>Chuy\u1ec7n g\u00ec s\u1ebd x\u1ea3y ra n\u1ebfu t\u00f4i g\u1eb7p ph\u1ea3i c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ee5 nghi\u00eam tr\u1ecdng?<\/h2>\n<p>B\u1ea1n c\u1ea7n th\u00f4ng b\u00e1o ngay cho nh\u00f3m nghi\u00ean c\u1ee9u v\u00e0 s\u1ebd nh\u1eadn \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb t\u1eeb h\u1ecd. Ph\u1ea3n \u1ee9ng ph\u1ee5 c\u0169ng l\u00e0 m\u1ed9t trong c\u00e1c th\u00f4ng s\u1ed1 m\u00e0 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ph\u1ea3i \u0111\u00e1nh gi\u00e1 v\u00e0 ghi l\u1ea1i. N\u1ebfu c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ee5 qu\u00e1 nghi\u00eam tr\u1ecdng, b\u1ea1n c\u00f3 th\u1ec3 xin r\u00fat kh\u1ecfi nghi\u00ean c\u1ee9u. B\u00ean c\u1ea1nh \u0111\u00f3, n\u1ebfu th\u1eed nghi\u1ec7m g\u00e2y ra ph\u1ea3n \u1ee9ng ph\u1ee5 qu\u00e1 nghi\u00eam tr\u1ecdng, Ban ki\u1ec3m so\u00e1t d\u1eef li\u1ec7u v\u00e0 an to\u00e0n (DSMB) c\u00f3 th\u1ec3 quy\u1ebft \u0111\u1ecbnh d\u1eebng nghi\u00ean c\u1ee9u.<\/p>\n<h2>Chuy\u1ec7n g\u00ec s\u1ebd x\u1ea3y ra n\u1ebfu t\u00f4i \u0111\u01b0\u1ee3c chuy\u1ec3n sang m\u1ed9t nh\u00f3m kh\u00e1c?<\/h2>\n<p>C\u00e1ch \u0111i\u1ec1u tr\u1ecb trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u00f4i khi cho th\u1ea5y s\u1ef1 \u01b0u vi\u1ec7t h\u01a1n so v\u1edbi \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n. Trong t\u00ecnh hu\u1ed1ng \u0111\u00f3, Ban ki\u1ec3m so\u00e1t d\u1eef li\u1ec7u va an to\u00e0n (DSMB) c\u00f3 th\u1ec3 mu\u1ed1n m\u1ecdi th\u00e0nh vi\u00ean trong nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c h\u01b0\u1edfng l\u1ee3i \u00edch t\u1eeb \u0111i\u1ec1u tr\u1ecb c\u1ee7a th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c chuy\u1ec3n sang nh\u00f3m kia (cross-over) \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ti\u1ebfp nh\u01b0ng \u0111i\u1ec1u n\u00e0y t\u00f9y thu\u1ed9c kh\u00e1 nhi\u1ec1u v\u00e0o k\u1ebf ho\u1ea1ch nghi\u00ean c\u1ee9u \u0111\u00e3 \u0111\u01b0\u1ee3c v\u1ea1ch ra t\u1eeb ban \u0111\u1ea7u.<\/p>\n<h2>T\u00f4i c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c cho u\u1ed1ng gi\u1ea3 d\u01b0\u1ee3c ho\u1eb7c \u201cvi\u00ean \u0111\u01b0\u1eddng\u201d hay kh\u00f4ng?<\/h2>\n<p>Gi\u1ea3 d\u01b0\u1ee3c (placebo) l\u00e0 thu\u1ed1c c\u00f3 b\u1ec1 ngo\u00e0i tr\u00f4ng nh\u01b0 thu\u1ed1c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nh\u01b0ng th\u1ef1c t\u1ebf kh\u00f4ng c\u00f3 d\u01b0\u1ee3c t\u00ednh v\u00e0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb b\u1ec7nh. Trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng v\u1ec1 ung th\u01b0, c\u00e1c b\u00e1c s\u0129 th\u01b0\u1eddng ti\u1ebfn h\u00e0nh so s\u00e1nh ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi so v\u1edbi \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n. Khi \u0111\u00f3, gi\u1ea3 d\u01b0\u1ee3c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng k\u00e8m theo nh\u00f3m \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c m\u1edbi ch\u00ednh x\u00e1c h\u01a1n. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 b\u1ea1n s\u1ebd v\u1eabn \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb theo c\u00e1ch ti\u00eau chu\u1ea9n hi\u1ec7n t\u1ea1i trong tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng \u0111\u01b0\u1ee3c ph\u00e2n v\u00e0o nh\u00f3m th\u1eed nghi\u1ec7m thu\u1ed1c m\u1edbi. N\u1ebfu c\u00f3 kh\u1ea3 n\u0103ng \u0111\u01b0\u1ee3c ph\u00e2n v\u00e0o nh\u00f3m d\u00f9ng gi\u1ea3 d\u01b0\u1ee3c, b\u1ea1n s\u1ebd \u0111\u01b0\u1ee3c th\u00f4ng b\u00e1o tr\u01b0\u1edbc khi k\u00ed t\u00ean v\u00e0o \u201cPhi\u1ebfu ch\u1ea5p thu\u1eadn tham gia nghi\u00ean c\u1ee9u\u201d. H\u00e3y h\u1ecfi th\u00e0nh vi\u00ean c\u1ee7a nh\u00f3m nghi\u00ean c\u1ee9u v\u1ec1 nh\u1eefng \u0111i\u1ec1u b\u1ea1n ch\u01b0a hi\u1ec3u v\u00ec quy\u1ec1n l\u1ee3i c\u1ee7a m\u00ecnh.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p><a href=\"https:\/\/www.cancer.net\/research-and-advocacy\/clinical-trials\/patient-safety-clinical-trials\" target=\"_blank\" rel=\"noopener\">https:\/\/www.cancer.net\/research-and-advocacy\/clinical-trials\/patient-safety-clinical-trials<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>An to\u00e0n b\u1ec7nh nh\u00e2n l\u00e0 v\u1ea5n \u0111\u1ec1 \u0111\u01b0\u1ee3c quan t\u00e2m h\u00e0ng \u0111\u1ea7u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. \u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao m\u1ed7i m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u1ec1u ph\u1ea3i tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t c\u00e1c quy tr\u00ecnh ki\u1ec3m tra.<\/p>\n","protected":false},"author":62,"featured_media":12121,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[3853,3203],"series":[3817],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>An to\u00e0n b\u1ec7nh nh\u00e2n trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng (Patient safety in Clinical Trials)<\/title>\n<meta name=\"description\" content=\"An to\u00e0n b\u1ec7nh nh\u00e2n l\u00e0 v\u1ea5n \u0111\u1ec1 \u0111\u01b0\u1ee3c quan t\u00e2m h\u00e0ng \u0111\u1ea7u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. \u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao m\u1ed7i m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u1ec1u ph\u1ea3i tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t c\u00e1c quy tr\u00ecnh ki\u1ec3m tra.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/ung-thu\/an-toan-benh-nhan-trong-thu-nghiem-lam-sang\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An to\u00e0n b\u1ec7nh nh\u00e2n trong th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng (Patient safety in Clinical Trials)\" \/>\n<meta property=\"og:description\" content=\"An to\u00e0n b\u1ec7nh nh\u00e2n l\u00e0 v\u1ea5n \u0111\u1ec1 \u0111\u01b0\u1ee3c quan t\u00e2m h\u00e0ng \u0111\u1ea7u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. \u0110\u00f3 l\u00e0 l\u00fd do v\u00ec sao m\u1ed7i m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u1ec1u ph\u1ea3i tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t c\u00e1c quy tr\u00ecnh ki\u1ec3m tra.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/yhoccongdong.com\/ung-thu\/an-toan-benh-nhan-trong-thu-nghiem-lam-sang\/\" \/>\n<meta property=\"og:site_name\" content=\"D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta property=\"article:published_time\" content=\"2018-07-11T19:56:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2018\/07\/an-toan-benh-nhan-trong-thu-nghiem-lam-sang.png\" \/>\n\t<meta property=\"og:image:width\" content=\"660\" \/>\n\t<meta property=\"og:image:height\" content=\"330\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Ths. 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