{"id":12487,"date":"2018-10-07T16:14:08","date_gmt":"2018-10-07T09:14:08","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/vai-tro-cua-viem-man-tinh-voi-ung-thu-ban-co-biet\/"},"modified":"2018-10-07T16:14:08","modified_gmt":"2018-10-07T09:14:08","slug":"vai-tro-cua-viem-man-tinh-voi-ung-thu-ban-co-biet","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/vai-tro-cua-viem-man-tinh-voi-ung-thu-ban-co-biet\/","title":{"rendered":"Vai tr\u00f2 c\u1ee7a vi\u00eam m\u1ea1n t\u00ednh v\u1edbi ung th\u01b0: b\u1ea1n c\u00f3 bi\u1ebft?"},"content":{"rendered":"<p style=\"text-align: justify\"><em>Bi\u00ean d\u1ecbch<\/em>: <strong>Ch\u00e2u Ti\u1ec3u Lan<\/strong><\/p>\n<p style=\"text-align: justify\">Ung th\u01b0 l\u00e0 b\u1ec7nh c\u00f3 li\u00ean quan \u0111\u1ebfn gene. C\u00e1c \u0111\u1ed9t bi\u1ebfn tr\u00ean DNA g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng gi\u1eefa hi\u1ec7n t\u01b0\u1ee3ng \u201csinh ra\u201d v\u00e0 \u201cch\u1ebft \u0111i\u201d c\u1ee7a t\u1ebf b\u00e0o, l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o m\u1ed9t c\u00e1ch b\u1ea5t th\u01b0\u1eddng. \u0110\u00e2y ch\u00ednh l\u00e0 c\u01a1 ch\u1ebf sinh b\u1ec7nh. C\u00f2n nguy\u00ean nh\u00e2n \u0111\u01b0a \u0111\u1ebfn c\u00e1c \u0111\u1ed9t bi\u1ebfn th\u00ec g\u1ed3m nhi\u1ec1u y\u1ebfu t\u1ed1, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 (risk factors), trong \u0111\u00f3, tu\u1ed5i t\u00e1c, r\u01b0\u1ee3u, c\u00e1c ch\u1ea5t g\u00e2y ung th\u01b0, vi\u00eam m\u00e3n t\u00ednh, dinh d\u01b0\u1ee1ng, hormone, \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch, c\u00e1c y\u1ebfu t\u1ed1 g\u00e2y vi\u00eam nhi\u1ec5m, b\u00e9o ph\u00ec, tia b\u1ee9c x\u1ea1, n\u1eafng, thu\u1ed1c l\u00e1\u2026l\u00e0 c\u00e1c y\u1ebfu t\u1ed1 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u nhi\u1ec1u nh\u1ea5t.<\/p>\n<p style=\"text-align: justify\">Ngo\u00e0i v\u1ea5n \u0111\u1ec1 tu\u1ed5i t\u00e1c v\u1ed1n kh\u00f4ng th\u1ec3 tr\u00e1nh kh\u1ecfi, c\u00e1c y\u1ebfu t\u1ed1 kh\u00e1c n\u1ebfu c\u00f3 hi\u1ec3u bi\u1ebft \u0111\u00fang \u0111\u1eafn th\u00ec s\u1ebd gi\u00fap ch\u00fang ta h\u1ea1n ch\u1ebf \u0111\u01b0\u1ee3c ph\u1ea7n n\u00e0o nguy c\u01a1 m\u1eafc b\u1ec7nh.<\/p>\n<ul style=\"text-align: justify\">\n<li>Ph\u00f2ng tr\u00e1nh c\u1ea5p \u0111\u1ed9 1: Gi\u1ea3m\/Tr\u00e1nh ti\u1ebfp x\u00fac v\u1edbi y\u1ebfu t\u1ed1 nguy c\u01a1.<\/li>\n<li>Ph\u00f2ng tr\u00e1nh c\u1ea5p \u0111\u1ed9 2: Ph\u00e1t hi\u1ec7n ung th\u01b0 t\u1eeb giai \u0111o\u1ea1n r\u1ea5t s\u1edbm, ngay khi ch\u01b0a c\u00f3 tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng r\u00f5 r\u1ec7t, khi t\u1ebf b\u00e0o ung th\u01b0 ch\u01b0a di c\u0103n, th\u00f4ng qua c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh t\u1ea7m so\u00e1t (screening procedures).<\/li>\n<li>Ph\u00f2ng tr\u00e1nh c\u1ea5p \u0111\u1ed9 3: S\u1eed d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p nh\u01b0 ph\u00f2ng v\u1ec7 mi\u1ec5n d\u1ecbch (immunoprevention) b\u1eb1ng c\u00e1ch ti\u00eam vaccines hay thu\u1ed1c ph\u00f2ng v\u1ec7 (chemoprevention). Thu\u1ed1c ph\u00f2ng v\u1ec7 hi\u1ec7n nay ch\u1ec9 c\u00f3 m\u1ed9t s\u1ed1 \u00edt \u0111\u01b0\u1ee3c cho ph\u00e9p, trong \u0111\u00f3 c\u00e1c c\u00f3 c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam th\u00f4ng d\u1ee5ng (d\u01b0\u1edbi ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129).<\/li>\n<\/ul>\n<h2 style=\"text-align: justify\">T\u1ea1i sao l\u00e0 thu\u1ed1c kh\u00e1ng vi\u00eam?<\/h2>\n<p style=\"text-align: justify\">Trong c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1, vi\u00eam m\u00e3n t\u00ednh c\u00f3 m\u1ed9t v\u1ecb tr\u00ed \u0111\u00e1ng k\u1ec3, lu\u00f4n c\u00f3 vai tr\u00f2 trong m\u1ecdi giai \u0111o\u1ea1n c\u1ee7a b\u1ec7nh ung th\u01b0: kh\u1edfi ph\u00e1t, ti\u1ebfn tri\u1ec3n v\u00e0 di c\u0103n, t\u00e1i ph\u00e1t, v\u00e0 c\u1ea3 \u0111\u1ec1 kh\u00e1ng thu\u1ed1c ung th\u01b0.<\/p>\n<p style=\"text-align: justify\">M\u1ed1i li\u00ean h\u1ec7 gi\u1eefa ph\u1ea3n \u1ee9ng vi\u00eam (inflammation) v\u00e0 ung th\u01b0 \u0111\u01b0\u1ee3c l\u1ea7n \u0111\u1ea7u ph\u00e1t hi\u1ec7n nh\u1edd v\u00e0o quan s\u00e1t c\u1ee7a b\u00e1c s\u0129 v\u00e0 nh\u00e0 nghi\u00ean c\u1ee9u Rudolf Ludwig Carl Virchow t\u1eeb v\u00e0o n\u0103m 1863, khi \u00f4ng ph\u00e1t hi\u1ec7n c\u00f3 c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u hi\u1ec7n di\u1ec7n g\u1ea7n c\u00e1c m\u00f4 ung th\u01b0. Th\u00f4ng qua vi\u1ec7c m\u00f4 t\u1ea3 m\u1ed9t hi\u1ec7n t\u01b0\u1ee3ng lo\u1ea1n s\u1ea3n t\u1ebf b\u00e0o hay th\u01b0\u1eddng \u0111i \u0111\u00f4i v\u1edbi c\u00e1c thay \u0111\u1ed5i trong qu\u00e1 tr\u00ecnh sinh l\u00fd l\u00e0m l\u00e0nh v\u1ebft th\u01b0\u01a1ng, \u00f4ng cho r\u1eb1ng ch\u00ednh ph\u1ea3n \u1ee9ng vi\u00eam t\u1ea1o ti\u1ec1n \u0111\u1ec1 cho ung th\u01b0 ph\u00e1t tri\u1ec3n. Su\u1ed1t h\u01a1n hai th\u1eadp ni\u00ean qua, t\u1eeb nh\u1eefng n\u0103m cu\u1ed1i th\u1ebf k\u1ef7 20 ng\u00e0y c\u00e0ng c\u00f3 nhi\u1ec1u b\u1eb1ng ch\u1ee9ng khoa h\u1ecdc \u0111\u01b0\u1ee3c t\u00edch l\u0169y v\u00e0 \u1ee7ng h\u1ed9 cho m\u1ed1i t\u01b0\u01a1ng t\u00e1c n\u00e0y.<\/p>\n<p style=\"text-align: justify\">Ph\u1ea3n \u1ee9ng vi\u00eam (s\u01b0ng, n\u00f3ng, \u0111\u1ecf, \u0111au) v\u1ed1n l\u00e0 m\u1ed9t ph\u1ea3n \u1ee9ng c\u00f3 l\u1ee3i c\u1ee7a c\u01a1 th\u1ec3 \u0111\u1ec3 \u0111\u01b0\u01a1ng \u0111\u1ea7u v\u1edbi c\u00e1c t\u1ed5n th\u01b0\u01a1ng m\u00f4. H\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch \u0111\u01b0\u1ee3c huy \u0111\u1ed9ng \u0111\u1ec3 \u0111i\u1ec1u \u0111\u1ed9ng c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u t\u1eeb h\u1ec7 b\u1ea1ch huy\u1ebft v\u00e0o v\u1ecb tr\u00ed b\u1ecb th\u01b0\u01a1ng t\u1ed5n nh\u1eb1m m\u1ee5c \u0111\u00edch l\u00e0m l\u00e0nh v\u1ebft th\u01b0\u01a1ng. C\u00e1c ph\u1ea3n \u1ee9ng n\u00e0y c\u00f3 c\u00e1c c\u01a1 ch\u1ebf t\u1ef1 \u0111i\u1ec1u ch\u1ec9nh v\u00e0 ch\u1ea5m d\u1ee9t m\u1ed9t khi c\u00e1c y\u1ebfu t\u1ed1 x\u00e2m h\u1ea1i \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf v\u00e0 qu\u00e1 tr\u00ecnh l\u00e0m l\u00e0nh v\u1ebft th\u01b0\u01a1ng \u0111\u01b0\u1ee3c ho\u00e0n t\u1ea5t. Tuy nhi\u00ean n\u1ebfu v\u00ec m\u1ed9t l\u00fd do n\u00e0o \u0111\u00f3, c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam b\u1ecb m\u1ea5t kh\u1ea3 n\u0103ng t\u1ef1 ki\u1ec3m so\u00e1t th\u00ec ch\u00fang s\u1ebd ti\u1ebfp t\u1ee5c qu\u00e1 tr\u00ecnh n\u00e0y dai d\u1eb3ng, v\u00e0 tr\u1edf th\u00e0nh vi\u00eam m\u00e3n t\u00ednh. Ch\u00ednh hi\u1ec7n t\u01b0\u1ee3ng vi\u00eam m\u00e3n n\u00e0y, v\u1edbi h\u1ec7 qu\u1ea3 l\u00e0 h\u00e0m l\u01b0\u1ee3ng c\u00e1c y\u1ebfu t\u1ed1 k\u00edch th\u00edch t\u1ebf b\u00e0o sinh tr\u01b0\u1edfng (groth factors), g\u1ed1c t\u1ef1 do oxi h\u00f3a (ROS) hay g\u1ed1c t\u1ef1 do nito h\u00f3a (NOS) b\u1ecb t\u0103ng cao s\u1ebd l\u00e0m th\u00fac \u0111\u1ea9y s\u1ef1 h\u00ecnh th\u00e0nh c\u00e1c \u0111\u1ed9t bi\u1ebfn gene g\u00e2y kh\u1edfi ph\u00e1t ung th\u01b0. Ngo\u00e0i ra trong qu\u00e1 tr\u00ecnh vi\u00eam m\u00e3n, nhi\u1ec1u t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch s\u1ebd li\u00ean t\u1ee5c ho\u1ea1t \u0111\u1ed9ng, nh\u01b0ng ch\u00fang kh\u00f4ng \u0111\u1ee7 kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 c\u01a1 th\u1ec3 n\u1eefa m\u00e0 ng\u01b0\u1ee3c l\u1ea1i c\u00f2n l\u00e0m h\u1ea1i c\u01a1 th\u1ec3 h\u01a1n v\u00ec v\u00f4 t\u00ecnh th\u00fac \u0111\u1ea9y cho c\u00e1c giai \u0111o\u1ea1n b\u1ec7nh ung th\u01b0 ng\u00e0y c\u00e0ng ph\u00e1t tri\u1ec3n.<\/p>\n<p style=\"text-align: justify\">C\u00e1c nghi\u00ean c\u1ee9u d\u1ecbch t\u1ec5 h\u1ecdc cho th\u1ea5y c\u00f3 \u00edt nh\u1ea5t 20% c\u00e1c lo\u1ea1i b\u1ec7nh ung th\u01b0 kh\u1edfi ngu\u1ed3n tr\u1ef1c ti\u1ebfp t\u1eeb b\u1ec7nh vi\u00eam m\u00e3n t\u00ednh.<\/p>\n<p style=\"text-align: justify\">N\u1ebfu nh\u01b0 c\u00e1c \u0111\u1ed9t bi\u1ebfn gene l\u00e0 que di\u00eam ch\u00e2m ng\u00f2i cho ung th\u01b0 th\u00ec hi\u1ec7n t\u01b0\u1ee3ng vi\u00eam l\u00e0 ngu\u1ed3n nhi\u00ean li\u1ec7u ti\u1ebfp t\u1ee5c s\u1ef1 thi\u00eau \u0111\u1ed1t \u0111\u00f3. Ngo\u00e0i ra ph\u1ea3n \u1ee9ng vi\u00eam c\u00f2n l\u00e0 c\u01a1 ch\u1ebf chung cho nhi\u1ec1u y\u1ebfu t\u1ed1 nguy c\u01a1 \u0111\u00e3 li\u1ec7t k\u00ea \u1edf tr\u00ean (r\u01b0\u1ee3u, thu\u1ed1c l\u00e1, b\u00e9o ph\u00ec,\u2026).<\/p>\n<p style=\"text-align: justify\">\u1ede c\u00e1c n\u01b0\u1edbc k\u00e9m ph\u00e1t tri\u1ec3n, t\u1ea7n su\u1ea5t ung th\u01b0 cao c\u00f3 ph\u1ea7n do c\u00e1c b\u1ec7nh vi\u00eam nhi\u1ec5m m\u00e3n t\u00ednh (vi khu\u1ea9n, virus do \u0111i\u1ec1u ki\u1ec7n v\u1ec7 sinh v\u00e0 ngu\u1ed3n n\u01b0\u1edbc u\u1ed1ng&#8230;); trong khi \u0111\u00f3 \u1edf c\u00e1c n\u01b0\u1edbc ph\u00e1t tri\u1ec3n, t\u00ecnh tr\u1ea1ng b\u00e9o ph\u00ec l\u00e0 m\u1ed9t y\u1ebfu t\u1ed1 nguy c\u01a1 do kh\u1ea3 n\u0103ng g\u00e2y t\u00e1c \u0111\u1ed9ng x\u1ea5u l\u00e0m qu\u00e1 tr\u00ecnh vi\u00eam b\u1ecb m\u1ea5t ki\u1ec3m so\u00e1t.<\/p>\n<p style=\"text-align: justify\">Hi\u1ec3u vai tr\u00f2 c\u1ee7a hi\u1ec7n t\u01b0\u1ee3ng vi\u00eam \u0111\u1ed1i v\u1edbi b\u1ec7nh ung th\u01b0, ch\u00fang ta s\u1ebd c\u00e0ng hi\u1ec3u h\u01a1n v\u00ec sao ung th\u01b0 kh\u00f4ng ph\u1ea3i l\u00e0 tr\u00f2 may r\u1ee7i c\u1ee7a s\u1ed1 ph\u1eadn. Ch\u00ednh l\u1ed1i s\u1ed1ng c\u1ee7a ch\u00fang ta s\u1ebd \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c qu\u00e1 tr\u00ecnh sinh l\u00fd trong c\u01a1 th\u1ec3, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho hi\u1ec7n t\u01b0\u1ee3ng vi\u00eam m\u1ea5t ki\u1ec3m so\u00e1t c\u00f3 th\u1ec3 di\u1ec5n ra b\u1ea5t c\u1ee9 l\u00fac n\u00e0o.<\/p>\n<p style=\"text-align: justify\">M\u1ed9t v\u00e0i lo\u1ea1i ung th\u01b0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3m nguy c\u01a1 m\u1eafc n\u1ebfu m\u1ecdi ng\u01b0\u1eddi bi\u1ebft ph\u00f2ng ng\u1eeba vi\u00eam nhi\u1ec5m vi khu\u1ea9n (H pylori- ung th\u01b0 d\u1ea1 d\u00e0y) hay virus (HBV- ung th\u01b0 gan; HPV-ung th\u01b0 c\u1ed5 t\u1eed cung\u2026).Tuy nhi\u00ean t\u1eebng tr\u01b0\u1eddng h\u1ee3p c\u1ee5 th\u1ec3 s\u1ebd l\u1ea7n l\u01b0\u1ee3t \u0111\u1ec1 c\u1eadp chi ti\u1ebft h\u01a1n \u1edf nh\u1eefng b\u00e0i sau.<\/p>\n<p style=\"text-align: justify\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-24574 size-full\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2018\/10\/vai-tro-viem-man-tinh-voi-ung-thu.jpg\" alt=\"vai-tro-viem-man-tinh-voi-ung-thu\" width=\"660\" height=\"330\" \/><\/p>\n<h2 style=\"text-align: justify\">T\u00e0i li\u00eau tham kh\u1ea3o:<\/h2>\n<ol style=\"text-align: justify\">\n<li><a href=\"https:\/\/www.cancer.gov\/about-cancer\/causes-prevention\/risk\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.cancer.gov\/about-cancer\/causes-prevention\/risk<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/nature01322.pdf\" target=\"_blank\" rel=\"noopener\">https:\/\/www.nature.com\/articles\/nature01322.pdf<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/nrclinonc.2015.105\" target=\"_blank\" rel=\"noopener\">https:\/\/www.nature.com\/articles\/nrclinonc.2015.105<\/a><\/li>\n<li><a href=\"http:\/\/www.cancernetwork.com\/\u2026\/chronic-inflammation-and-can\" target=\"_blank\" rel=\"noopener\">http:\/\/www.cancernetwork.com\/\u2026\/chronic-inflammation-and-can<\/a><\/li>\n<li><a href=\"http:\/\/cancerpreventionresearch.aacrjournals.org\/cont\u2026\/\u2026\/895\" target=\"_blank\" rel=\"noopener\">http:\/\/cancerpreventionresearch.aacrjournals.org\/cont\u2026\/\u2026\/895<\/a><\/li>\n<\/ol>\n<p style=\"text-align: justify\">B\u1ea3ng danh s\u00e1ch b\u1ec7nh v\u00e0 nguy c\u01a1 \u0111\u01b0\u1ee3c l\u1ea5y t\u1eeb b\u00e0i vi\u1ebft trong link n\u00e0y:\u00a0<a href=\"http:\/\/benhvien108.vn\/khoakhambenh\/tinbai\/1937\/viem-man-tinh-va-ung-thu\" target=\"_blank\" rel=\"noopener nofollow\">http:\/\/benhvien108.vn\/\u2026\/tinbai\/1937\/viem-man-tinh-va-ung-thu<\/a><\/p>\n<p style=\"text-align: justify\">Ghi ch\u00fa: b\u00e0i vi\u1ebft kh\u00f4ng nh\u1eb1m m\u1ee5c \u0111\u00edch \u0111em l\u1ea1i l\u1eddi khuy\u00ean ch\u1eefa tr\u1ecb n\u00e0o cho c\u00e1c b\u1ec7nh nh\u00e2n. V\u1edbi c\u00e1c t\u00ecnh hu\u1ed1ng b\u1ec7nh c\u1ee5 th\u1ec3, b\u1ec7nh nh\u00e2n ph\u1ea3i li\u00ean h\u1ec7 v\u1edbi b\u00e1c s\u0129 c\u1ee7a m\u00ecnh.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ung th\u01b0 l\u00e0 b\u1ec7nh c\u00f3 li\u00ean quan \u0111\u1ebfn gene. C\u00e1c \u0111\u1ed9t bi\u1ebfn tr\u00ean DNA g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng gi\u1eefa hi\u1ec7n t\u01b0\u1ee3ng \u201csinh ra\u201d v\u00e0 \u201cch\u1ebft \u0111i\u201d c\u1ee7a t\u1ebf b\u00e0o, l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o m\u1ed9t c\u00e1ch b\u1ea5t th\u01b0\u1eddng. \u0110\u00e2y ch\u00ednh l\u00e0 C\u01a0 CH\u1ebe sinh b\u1ec7nh.<\/p>\n","protected":false},"author":14,"featured_media":12486,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[2476,3980],"series":[3976],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vai tr\u00f2 c\u1ee7a vi\u00eam m\u1ea1n t\u00ednh v\u1edbi ung th\u01b0: b\u1ea1n c\u00f3 bi\u1ebft?<\/title>\n<meta name=\"description\" content=\"Vai tr\u00f2 c\u1ee7a vi\u00eam m\u1ea1n t\u00ednh v\u1edbi ung th\u01b0: b\u1ea1n c\u00f3 bi\u1ebft? 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