{"id":8267,"date":"2019-11-02T00:56:48","date_gmt":"2019-11-01T17:56:48","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/khoi-u-wilms-o-tre-em-yeu-to-nguy-co\/"},"modified":"2019-11-02T00:56:48","modified_gmt":"2019-11-01T17:56:48","slug":"khoi-u-wilms-o-tre-em-yeu-to-nguy-co","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/khoi-u-wilms-o-tre-em-yeu-to-nguy-co\/","title":{"rendered":"Kh\u1ed1i u Wilms \u1edf tr\u1ebb em: Y\u1ebfu t\u1ed1 nguy c\u01a1"},"content":{"rendered":"<p style=\"text-align: right\"><em><strong>Bi\u00ean d\u1ecbch: Phan Th\u1ecb Thanh H\u01b0\u01a1ng<\/strong><\/em><\/p>\n<p style=\"text-align: right\"><em><strong>Hi\u1ec7u \u0111\u00ednh: Ths.Bs <a href=\"https:\/\/yhoccongdong.com\/profile\/nguyen-hai-nam\/\" target=\"_blank\" rel=\"noopener\">Nguy\u1ec5n H\u1ea3i Nam<\/a>, <a href=\"https:\/\/yhoccongdong.com\/profile\/chaulhc\/\" target=\"_blank\" rel=\"noopener\">L\u00ea H\u00e0 C\u1ea3nh Ch\u00e2u<\/a><\/strong><\/em><\/p>\n<p><em><strong>B\u00e0i vi\u1ebft n\u00e0y gi\u1edbi thi\u1ec7u v\u1ec1 c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng m\u1eafc u Wilms (u nguy\u00ean b\u00e0o th\u1eadn). H\u00e3y s\u1eed d\u1ee5ng menu \u0111\u1ec3 xem c\u00e1c b\u00e0i vi\u1ebft kh\u00e1c.<\/strong><\/em><\/p>\n<p><span style=\"color: #ff0000\"><strong>Y\u1ebfu t\u1ed1 nguy c\u01a1<\/strong><\/span> l\u00e0 b\u1ea5t k\u00ec y\u1ebfu t\u1ed1 n\u00e0o l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng m\u1eafc ung th\u01b0 \u1edf m\u1ed9t ng\u01b0\u1eddi. M\u1eb7c d\u00f9 c\u00e1c y\u1ebfu t\u1ed1 n\u00e0y th\u01b0\u1eddng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh kh\u1edfi ph\u00e1t v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a u Wilms, nh\u01b0ng h\u1ea7u h\u1ebft ch\u00fang kh\u00f4ng tr\u1ef1c ti\u1ebfp g\u00e2y ra b\u1ec7nh. M\u1ed9t s\u1ed1 tr\u1ebb c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0ng kh\u00f4ng xu\u1ea5t hi\u1ec7n kh\u1ed1i u, trong khi nh\u1eefng tr\u1ebb kh\u00e1c l\u1ea1i m\u1eafc b\u1ec7nh m\u00e0 kh\u00f4ng c\u00f3 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn.<\/p>\n<p><span style=\"color: #ff0000\"><strong>U Wilms (u nguy\u00ean b\u00e0o th\u1eadn)<\/strong> <\/span>th\u01b0\u1eddng kh\u00f4ng mang t\u00ednh di truy\u1ec1n, nh\u01b0ng c\u00f3 m\u1ed9t s\u1ed1 nguy\u00ean nh\u00e2n v\u1ec1 gen c\u00f3 li\u00ean quan \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a u.<\/p>\n<ul>\n<li><strong>Bi\u1ebfn \u0111\u1ed5i di truy\u1ec1n.\u00a0<\/strong>Tr\u1ebb c\u00f3 th\u1ec3 c\u00f3 c\u00e1c gen b\u1ecb \u0111\u1ed9t bi\u1ebfn, h\u01b0 h\u1ecfng ho\u1eb7c khuy\u1ebft. C\u00e1c bi\u1ebfn \u0111\u1ed5i n\u00e0y c\u0169ng g\u00e2y ra d\u1ecb t\u1eadt b\u1ea9m sinh kh\u00e1c. Kho\u1ea3ng 15% tr\u1ebb m\u1eafc b\u1ec7nh u Wilms \u0111\u01b0\u1ee3c sinh ra k\u00e8m theo c\u00e1c v\u1ea5n \u0111\u1ec1 s\u1ee9c kh\u1ecfe kh\u00e1c.<\/li>\n<li><strong>H\u1ed9i ch\u1ee9ng WAGR.\u00a0<\/strong>H\u1ed9i ch\u1ee9ng WAGR l\u00e0 t\u00ecnh tr\u1ea1ng b\u1ec7nh g\u00e2y ra m\u1ed9t s\u1ed1 khuy\u1ebft t\u1eadt b\u1ea9m sinh. Tr\u1ebb m\u1eafc h\u1ed9i ch\u1ee9ng n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng m\u1eafc b\u1ec7nh u Wilms l\u00e0 33%. WAGR l\u00e0 vi\u1ebft t\u1eaft c\u1ee7a:\n<ul>\n<li>Wilms tumors: U Wilms<\/li>\n<li>Aniridia: D\u1ecb t\u1eadt m\u1ed1ng m\u1eaft (kh\u00f4ng c\u00f3 m\u1ed1ng)<\/li>\n<li>Genitourinary abnormalities: B\u1ea5t th\u01b0\u1eddng h\u1ec7 ti\u1ebft ni\u1ec7u &#8211; sinh d\u1ee5c. \u0110\u00f3 l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i c\u1ee7a c\u01a1 quan sinh d\u1ee5c v\u00e0 ti\u1ebft ni\u1ec7u, ho\u1eb7c l\u00e0 u nguy\u00ean b\u00e0o sinh d\u1ee5c (m\u1ed9t kh\u1ed1i u hi\u1ebfm g\u1eb7p c\u1ee7a c\u01a1 quan sinh s\u1ea3n).<\/li>\n<li>Intellectual disability: Khuy\u1ebft t\u1eadt tr\u00ed tu\u1ec7, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ch\u1eadm ph\u00e1t tri\u1ec3n tr\u00ed tu\u1ec7.<\/li>\n<\/ul>\n<\/li>\n<li><strong>H\u1ed9i ch\u1ee9ng Beckwith-Wiedemann<\/strong><strong>. <\/strong><a href=\"https:\/\/www.cancer.net\/cancer-types\/beckwith-wiedemann-syndrome\" target=\"_blank\" rel=\"noopener\">H\u1ed9i ch\u1ee9ng n\u00e0y<\/a> l\u00e0m gia t\u0103ng k\u00edch th\u01b0\u1edbc c\u1ee7a c\u00e1c c\u01a1 quan n\u1ed9i t\u1ea1ng v\u00e0 tay ch\u00e2n. Tr\u1ebb m\u1eafc h\u1ed9i ch\u1ee9ng n\u00e0y c\u00f3 nguy c\u01a1 cao m\u1eafc b\u1ec7nh u Wilms, nang th\u1eadn v\u00e0 nh\u1eefng kh\u1ed1i u gan (u nguy\u00ean b\u00e0o gan), t\u1ee5y v\u00e0 tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn.<\/li>\n<li><strong>H\u1ed9i ch\u1ee9ng Denys-Drash<\/strong><strong>.\u00a0<\/strong>H\u1ed9i ch\u1ee9ng n\u00e0y xu\u1ea5t hi\u1ec7n \u1edf c\u00e1c b\u00e9 trai c\u00f3 c\u01a1 quan sinh d\u1ee5c ph\u00e1t tri\u1ec3n kh\u00f4ng ho\u00e0n thi\u1ec7n. Nh\u1eefng tr\u1ebb m\u1eafc h\u1ed9i ch\u1ee9ng n\u00e0y c\u00f3 nguy c\u01a1 m\u1eafc b\u1ec7nh u Wilms cao h\u01a1n.<\/li>\n<li><strong>Ti\u1ec1n s\u1eed gia \u0111\u00ecnh.\u00a0<\/strong>M\u1ed9t s\u1ed1 \u00edt tr\u1ebb em m\u1eafc b\u1ec7nh u Wilms c\u00f3 ng\u01b0\u1eddi th\u00e2n trong gia \u0111\u00ecnh c\u0169ng m\u1eafc b\u1ec7nh.<\/li>\n<\/ul>\n<p><em><a href=\"https:\/\/www.cancer.net\/cancer-types\/wilms-tumor-childhood\/symptoms-and-signs\" target=\"_blank\" rel=\"noopener\">Ph\u1ea7n ti\u1ebfp theo trong h\u01b0\u1edbng d\u1eabn n\u00e0y l\u00e0 Tri\u1ec7u ch\u1ee9ng v\u00e0 D\u1ea5u hi\u1ec7u<\/a><\/em><em>. B\u00e0i vi\u1ebft g\u1ea3i th\u00edch nh\u1eefng bi\u1ebfn \u0111\u1ed5i c\u1ee7a c\u01a1 th\u1ec3 ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00e1c m\u00e0 <\/em><em>u Wilms<\/em><em> c\u00f3 th\u1ec3<\/em><em> g\u00e2y ra. S\u1eed d\u1ee5ng menu v\u00e0 ch\u1ecdn m\u1ed9t ph\u1ea7n kh\u00e1c \u0111\u1ec3 \u0111\u1ecdc trong h\u01b0\u1edbng d\u1eabn n\u00e0y.<\/em><\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p><a href=\"https:\/\/www.cancer.net\/cancer-types\/wilms-tumor-childhood\/risk-factors\" target=\"_blank\" rel=\"noopener\">Wilms Tumor &#8211; Childhood: Risk Factors<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gi\u1edbi thi\u1ec7u v\u1ec1 c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng m\u1eafc kh\u1ed1i u Wilms (u nguy\u00ean b\u00e0o th\u1eadn) \u1edf tr\u1ebb em.<\/p>\n","protected":false},"author":62,"featured_media":5509,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3140,2679],"tags":[3141,2489,2986],"series":[1989],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Kh\u1ed1i u Wilms \u1edf tr\u1ebb em: Y\u1ebfu t\u1ed1 nguy c\u01a1 - D\u1ef1 \u00e1n Ung Th\u01b0<\/title>\n<meta name=\"description\" content=\"Gi\u1edbi thi\u1ec7u v\u1ec1 c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng m\u1eafc kh\u1ed1i u Wilms (u nguy\u00ean b\u00e0o th\u1eadn) \u1edf tr\u1ebb em.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/ung-thu\/khoi-u-wilms-o-tre-em-yeu-to-nguy-co\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kh\u1ed1i u Wilms \u1edf tr\u1ebb em: Y\u1ebfu t\u1ed1 nguy c\u01a1 - D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta property=\"og:description\" content=\"Gi\u1edbi thi\u1ec7u v\u1ec1 c\u00e1c y\u1ebfu t\u1ed1 l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng m\u1eafc kh\u1ed1i u Wilms (u nguy\u00ean b\u00e0o th\u1eadn) \u1edf tr\u1ebb em.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/yhoccongdong.com\/ung-thu\/khoi-u-wilms-o-tre-em-yeu-to-nguy-co\/\" \/>\n<meta property=\"og:site_name\" content=\"D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta property=\"article:published_time\" content=\"2019-11-01T17:56:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2019\/11\/khoi-u-wilms-o-tre-em-yeu-to-nguy-co-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"660\" \/>\n\t<meta property=\"og:image:height\" content=\"330\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ths. 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