{"id":8472,"date":"2020-04-26T21:26:33","date_gmt":"2020-04-26T14:26:33","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/hoi-chung-polyp-juvenile\/"},"modified":"2020-04-26T21:26:33","modified_gmt":"2020-04-26T14:26:33","slug":"hoi-chung-polyp-juvenile","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/hoi-chung-polyp-juvenile\/","title":{"rendered":"H\u1ed9i ch\u1ee9ng Polyp Juvenile"},"content":{"rendered":"<p style=\"text-align: right;\"><strong><em>Bi\u00ean d\u1ecbch: Ho\u00e0ng M\u1ea1nh C\u01b0\u1eddng<\/em><\/strong><\/p>\n<p style=\"text-align: right;\"><strong><em>Hi\u1ec7u \u0111\u00ednh: TS.BS\u00a0<a href=\"https:\/\/yhoccongdong.com\/profile\/nguyen-thi-quynh-tho\/\" target=\"_blank\" rel=\"noopener\">Nguy\u1ec5n Th\u1ecb Qu\u1ef3nh Th\u01a1<\/a><\/em><\/strong><\/p>\n<h2><strong>H\u1ed9i ch\u1ee9ng polyp juvenile (JPS) l\u00e0 g\u00ec? <\/strong><\/h2>\n<p>H\u1ed9i ch\u1ee9ng polyp juvenile (JPS) l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a polyp hamartomatous trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.\u00a0Hamartomas l\u00e0 nh\u1eefng kh\u1ed1i u l\u00e0nh t\u00ednh c\u1ee7a m\u00f4 b\u00ecnh th\u01b0\u1eddng \u0111\u01b0\u1ee3c h\u00ecnh th\u00e0nh trong ru\u1ed9t ho\u1eb7c nh\u1eefng v\u1ecb tr\u00ed kh\u00e1c.\u00a0Nh\u1eefng kh\u1ed1i n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 polyp khi ch\u00fang ph\u00e1t tri\u1ec3n b\u00ean trong c\u00e1c c\u1ea5u tr\u00fac c\u01a1 th\u1ec3, ch\u1eb3ng h\u1ea1n nh\u01b0 ru\u1ed9t.\u00a0Thu\u1eadt ng\u1eef \u201cjuvenile polyposis\u201d \u0111\u1ec1 c\u1eadp \u0111\u1ebfn m\u1ed9t lo\u1ea1i polyp (g\u1ecdi l\u00e0 polyp juvenile) \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n khi ph\u00e2n t\u00edch polyp d\u01b0\u1edbi k\u00ednh hi\u1ec3n vi, ch\u1ee9 kh\u00f4ng li\u00ean quan t\u1edbi \u0111\u1ed9 tu\u1ed5i \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc JPS.<\/p>\n<p>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eafc JPS, polyp th\u01b0\u1eddng ph\u00e1t tri\u1ec3n trong \u0111\u1ed9 tu\u1ed5i 20 tu\u1ed5i. S\u1ed1 l\u01b0\u1ee3ng polyp m\u00e0 m\u1ed9t ng\u01b0\u1eddi c\u00f3 th\u1ec3 c\u00f3 trong \u0111\u1eddi dao \u0111\u1ed9ng t\u1eeb kho\u1ea3ng 5 \u0111\u1ebfn h\u01a1n 100. H\u1ea7u h\u1ebft c\u00e1c polyp \u0111\u1ec1u l\u00e0nh t\u00ednh (kh\u00f4ng ung th\u01b0), nh\u01b0ng n\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc ung th\u01b0 \u0111\u01b0\u1eddng ti\u00eau ho\u00e1, ch\u1eb3ng h\u1ea1n nh\u01b0 ung th\u01b0\u00a0<a href=\"https:\/\/yhoccongdong.com\/thongtin\/ung-thu-da-day\/\" target=\"_blank\" rel=\"noopener\"><strong>d\u1ea1 d\u00e0y<\/strong><\/a>,\u00a0<a href=\"https:\/\/www.cancer.net\/node\/31377\" target=\"_blank\" rel=\"noopener\"><strong>ru\u1ed9t non<\/strong><\/a>,\u00a0<a href=\"https:\/\/yhoccongdong.com\/thongtin\/ung-thu-dai-truc-trang\/\" target=\"_blank\" rel=\"noopener\"><strong>\u0111\u1ea1i tr\u00e0ng<\/strong>\u00a0v\u00e0\u00a0<strong>tr\u1ef1c tr\u00e0ng<\/strong><\/a> trong c\u00e1c gia \u0111\u00ecnh c\u00f3 JPS.<\/p>\n<p>Nghi ng\u1edd JPS khi c\u00e1c tri\u1ec7u ch\u1ee9ng v\u00e0 ti\u1ec1n s\u1eed gia \u0111\u00ecnh ph\u00f9 h\u1ee3p v\u1edbi b\u1ea5t k\u1ef3 \u0111\u1eb7c \u0111i\u1ec3m n\u00e0o sau \u0111\u00e2y:<\/p>\n<ul>\n<li>C\u00f3 h\u01a1n 5 polyp juvenile \u1edf \u0111\u1ea1i tr\u00e0ng v\u00e0\/ho\u1eb7c tr\u1ef1c tr\u00e0ng<\/li>\n<li>\u0110a polyp juvenile trong su\u1ed1t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a<\/li>\n<li>C\u00f3polyp juvenile b\u1ea5t k\u1ef3 s\u1ed1 l\u01b0\u1ee3ng v\u00e0 c\u00f3 ti\u1ec1n s\u1eed gia \u0111\u00ecnh m\u1eafc polyp juvenile.<\/li>\n<\/ul>\n<h2><strong>Nguy\u00ean nh\u00e2n g\u00e2y ra JPS?<\/strong><\/h2>\n<p>JPS l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd di truy\u1ec1n.\u00a0\u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 nguy c\u01a1 m\u1eafc b\u1ec7nh polyp v\u00e0 ung th\u01b0 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c truy\u1ec1n t\u1eeb th\u1ebf h\u1ec7 n\u00e0y sang th\u1ebf h\u1ec7 kh\u00e1c trong m\u1ed9t gia \u0111\u00ecnh.\u00a0C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y c\u00f3 2 gen li\u00ean quan t\u1edbi JPS l\u00e0\u00a0<em>BMPR1A<\/em>\u00a0v\u00e0\u00a0<em>SMAD4<\/em>.\u00a0M\u1ed9t \u0111\u1ed9t bi\u1ebfn (bi\u1ebfn \u0111\u1ed5i) trong gen\u00a0<em>BMPR1A<\/em>\u00a0ho\u1eb7c gen\u00a0<em>SMAD4<\/em>\u00a0l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng ph\u00e1t tri\u1ec3n polyp juvenile v\u00e0 ung th\u01b0 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a trong su\u1ed1t cu\u1ed9c \u0111\u1eddi.\u00a0Kh\u00f4ng ph\u1ea3i t\u1ea5t c\u1ea3 c\u00e1c gia \u0111\u00ecnh m\u1eafc JPS \u0111\u1ec1u c\u00f3 \u0111\u1ed9t bi\u1ebfn trong\u00a0<em>BMPR1A<\/em>\u00a0ho\u1eb7c\u00a0<em>SMAD4.<\/em>\u00a0C\u00e1c gen kh\u00e1c \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u m\u1ed1i li\u00ean quan c\u1ee7a ch\u00fang v\u1edbi JPS.<\/p>\n<h2><strong>JPS \u0111\u01b0\u1ee3c di truy\u1ec1n nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>Th\u00f4ng th\u01b0\u1eddng, m\u1ed7i t\u1ebf b\u00e0o c\u00f3 2 b\u1ea3n sao c\u1ee7a m\u1ed7i gen: 1 \u0111\u01b0\u1ee3c th\u1eeba h\u01b0\u1edfng t\u1eeb m\u1eb9 v\u00e0 1 t\u1eeb b\u1ed1. JPS tu\u00e2n theo ki\u1ec3u h\u00ecnh di truy\u1ec1n t\u00ednh tr\u1ed9 tr\u00ean NST th\u01b0\u1eddng, trong \u0111\u00f3 ch\u1ec9 c\u1ea7n m\u1ed9t \u0111\u1ed9t bi\u1ebfn x\u1ea3y ra trong 1 b\u1ea3n sao c\u1ee7a gen \u0111\u00e3 l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc b\u1ec7nh. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 b\u1ed1 m\u1eb9 mang m\u1ed9t \u0111\u1ed9t bi\u1ebfn gen c\u00f3 th\u1ec3 truy\u1ec1n cho con m\u1ed9t b\u1ea3n sao c\u1ee7a gen b\u00ecnh th\u01b0\u1eddng ho\u1eb7c m\u1ed9t b\u1ea3n sao c\u1ee7a gen c\u00f3 \u0111\u1ed9t bi\u1ebfn. Do v\u1eady, m\u1ed9t \u0111\u1ee9a tr\u1ebb c\u00f3 b\u1ed1 m\u1eb9 b\u1ecb \u0111\u1ed9t bi\u1ebfn c\u00f3 50% kh\u1ea3 n\u0103ng th\u1eeba h\u01b0\u1edfng \u0111\u1ed9t bi\u1ebfn \u0111\u00f3. Anh, ch\u1ecb em ho\u1eb7c b\u1ed1 m\u1eb9 c\u1ee7a ng\u01b0\u1eddi b\u1ecb \u0111\u1ed9t bi\u1ebfn c\u0169ng c\u00f3 50% kh\u1ea3 n\u0103ng mang \u0111\u1ed9t bi\u1ebfn t\u01b0\u01a1ng t\u1ef1. Tuy nhi\u00ean, n\u1ebfu k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m c\u1ee7a cha m\u1eb9 \u00e2m t\u00ednh v\u1edbi \u0111\u1ed9t bi\u1ebfn, nguy c\u01a1 \u0111\u1ed1i v\u1edbi anh ch\u1ecb em ru\u1ed9t gi\u1ea3m \u0111\u00e1ng k\u1ec3 nh\u01b0ng nguy c\u01a1 c\u1ee7a h\u1ecd v\u1eabn cao h\u01a1n m\u1ee9c trung b\u00ecnh.<\/p>\n<p>C\u00f3 nh\u1eefng l\u1ef1a ch\u1ecdn cho nh\u1eefng ng\u01b0\u1eddi mong mu\u1ed1n c\u00f3 con kho\u1ebb m\u1ea1nh khi h\u1ecd mang \u0111\u1ed9t bi\u1ebfn gen l\u00e0m t\u0103ng nguy c\u01a1 m\u1eafc h\u1ed9i ch\u1ee9ng ung th\u01b0 di truy\u1ec1n n\u00e0y.\u00a0Ch\u1ea9n \u0111o\u00e1n di truy\u1ec1n ti\u1ec1n l\u00e0m t\u1ed5 (PGD) l\u00e0 m\u1ed9t th\u1ee7 thu\u1eadt y khoa \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n k\u1ebft h\u1ee3p v\u1edbi th\u1ee5 tinh trong \u1ed1ng nghi\u1ec7m (IVF).\u00a0Th\u1ee7 thu\u1eadt n\u00e0y cho ph\u00e9p nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 bi\u1ebft mang m\u1ed9t \u0111\u1ed9t bi\u1ebfn gen c\u1ee5 th\u1ec3 gi\u1ea3m thi\u1ec3u kh\u1ea3 n\u0103ng con c\u00e1i h\u1ecd b\u1ecb di truy\u1ec1n \u0111\u1ed9t bi\u1ebfn n\u00e0y.\u00a0Trong ph\u01b0\u01a1ng ph\u00e1p n\u00e0y, tr\u1ee9ng c\u1ee7a ng\u01b0\u1eddi ph\u1ee5 n\u1eef s\u1ebd \u0111\u01b0\u1ee3c l\u1ea5y ra v\u00e0 th\u1ee5 tinh trong ph\u00f2ng th\u00ed nghi\u1ec7m.\u00a0Khi ph\u00f4i \u0111\u1ea1t \u0111\u1ebfn m\u1ed9t k\u00edch th\u01b0\u1edbc nh\u1ea5t \u0111\u1ecbnh, 1 t\u1ebf b\u00e0o s\u1ebd \u0111\u01b0\u1ee3c t\u00e1ch ra v\u00e0 ki\u1ec3m tra t\u00ecnh tr\u1ea1ng di truy\u1ec1n.\u00a0Sau \u0111\u00f3, b\u1ed1 m\u1eb9 c\u00f3 th\u1ec3 ch\u1ecdn chuy\u1ec3n ph\u00f4i kh\u00f4ng mang \u0111\u1ed9t bi\u1ebfn.\u00a0PGD \u200b\u200b\u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong h\u01a1n 2 th\u1eadp k\u1ef7 v\u00e0 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng cho m\u1ed9t s\u1ed1 h\u1ed9i ch\u1ee9ng ung th\u01b0 c\u00f3 khuynh h\u01b0\u1edbng di truy\u1ec1n.\u00a0Tuy nhi\u00ean, \u0111\u00e2y l\u00e0 m\u1ed9t th\u1ee7 thu\u1eadt ph\u1ee9c t\u1ea1p v\u1edbi nhi\u1ec1u v\u1ea5n \u0111\u1ec1 c\u1ea7n xem x\u00e9t tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u nh\u01b0 t\u00e0i ch\u00ednh, th\u1ec3 ch\u1ea5t v\u00e0 c\u1ea3m x\u00fac.\u00a0\u0110\u1ec3 bi\u1ebft th\u00eam th\u00f4ng tin, h\u00e3y n\u00f3i chuy\u1ec7n v\u1edbi chuy\u00ean gia h\u1ed7 tr\u1ee3 sinh s\u1ea3n t\u1ea1i ph\u00f2ng kh\u00e1m t\u01b0 v\u1ea5n sinh s\u1ea3n.<\/p>\n<h2><strong>JPS ph\u1ed5 bi\u1ebfn nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>Ng\u01b0\u1eddi ta \u01b0\u1edbc t\u00ednh r\u1eb1ng t\u1ef7 l\u1ec7 m\u1eafc JPS t\u1eeb 1\/16.000 \u0111\u1ebfn 1\/100.000 ng\u01b0\u1eddi.<\/p>\n<h2><strong>Ch\u1ea9n \u0111o\u00e1n JPS nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>Ch\u1ea9n \u0111o\u00e1n JPS \u0111\u01b0\u1ee3c kh\u1eb3ng \u0111\u1ecbnh n\u1ebfu c\u00e1c tri\u1ec7u ch\u1ee9ng v\u00e0 ti\u1ec1n s\u1eed gia \u0111\u00ecnh ph\u00f9 h\u1ee3p v\u1edbi b\u1ea5t k\u1ef3 ti\u00eau chu\u1ea9n n\u00e0o trong 3 ti\u00eau chu\u1ea9n \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea \u1edf tr\u00ean.\u00a0Nh\u1eefng ng\u01b0\u1eddi b\u1ecb JPS c\u00f3 th\u1ec3 x\u00e9t nghi\u1ec7m m\u00e1u \u0111\u1ec3 ph\u00e1t hi\u1ec7n \u0111\u1ed9t bi\u1ebfn gen\u00a0<em>BMPR1A<\/em>\u00a0ho\u1eb7c gen\u00a0<em>SMAD4<\/em>\u00a0.\u00a0Trong tr\u01b0\u1eddng h\u1ee3p t\u00ecm th\u1ea5y m\u1ed9t \u0111\u1ed9t bi\u1ebfn gen c\u1ee5 th\u1ec3, c\u00e1c th\u00e0nh vi\u00ean kh\u00e1c trong gia \u0111\u00ecnh c\u0169ng s\u1ebd \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc JPS n\u1ebfu k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m c\u1ee7a h\u1ecd c\u00f3 c\u00f9ng \u0111\u1ed9t bi\u1ebfn t\u01b0\u01a1ng t\u1ef1.<\/p>\n<p>C\u00f3 th\u1ec3 c\u00f3 c\u00e1c gen kh\u00e1c li\u00ean quan \u0111\u1ebfn JPS ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh, do v\u1eady, n\u1ebfu k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m m\u00e1u tr\u1ea3 v\u1ec1 l\u00e0 \u00e2m t\u00ednh (c\u00f3 ngh\u0129a l\u00e0 kh\u00f4ng t\u00ecm th\u1ea5y \u0111\u1ed9t bi\u1ebfn gen) th\u00ec c\u0169ng kh\u00f4ng th\u1ec3 kh\u1eb3ng \u0111\u1ecbnh ng\u01b0\u1eddi \u0111\u00f3 kh\u00f4ng m\u1eafc JPS .\u00a0Do \u0111\u00f3, tham v\u1ea5n chuy\u00ean gia di truy\u1ec1n \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho nh\u1eefng ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed gia \u0111\u00ecnh m\u1eafc JPS ho\u1eb7c c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng g\u1ee3i \u00fd JPS.<\/p>\n<h2><strong>C\u00e1c \u01b0\u1edbc t\u00ednh v\u1ec1 nguy c\u01a1 ung th\u01b0 li\u00ean quan \u0111\u1ebfn JPS nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>Nh\u1eefng ng\u01b0\u1eddi m\u1eafc JPS \u0111\u01b0\u1ee3c xem l\u00e0 c\u00f3 nguy c\u01a1 m\u1eafc ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, d\u1ea1 d\u00e0y, ru\u1ed9t non v\u00e0\u00a0t\u1ee5y.\u00a0\u01af\u1edbc t\u00ednh v\u1ec1 nguy c\u01a1 ung th\u01b0 chung li\u00ean quan \u0111\u1ebfn JPS l\u00e0 t\u1eeb 9% \u0111\u1ebfn 50%, nh\u01b0ng ch\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c nguy c\u01a1 \u0111\u1ed1i v\u1edbi t\u1eebng lo\u1ea1i ung th\u01b0 c\u1ee5 th\u1ec3.<\/p>\n<h2><strong>Nh\u1eefng nguy c\u01a1 kh\u00e1c li\u00ean quan \u0111\u1ebfn JPS l\u00e0 g\u00ec?<\/strong><\/h2>\n<p>Nh\u1eefng c\u00e1 nh\u00e2n mang \u0111\u1ed9t bi\u1ebfn gen\u00a0<em>SMAD4<\/em>\u00a0c\u00f3 nguy c\u01a1 m\u1eafc b\u1ec7nh gi\u00e3n m\u1ea1ch mao xu\u1ea5t huy\u1ebft di truy\u1ec1n (Hereditary Hemerrhagic Telangiectasia &#8211; HHT). Nh\u1eefng ng\u01b0\u1eddi m\u1eafc HHT th\u01b0\u1eddng b\u1ecb ch\u1ea3y m\u00e1u cam v\u00e0 c\u00f3 nguy c\u01a1 b\u1ecb ph\u00ecnh \u0111\u1ed9ng m\u1ea1ch v\u00e0 d\u1ecb d\u1ea1ng m\u1ea1ch m\u00e1u (AVMs) trong n\u00e3o v\u00e0 ph\u1ed5i.<\/p>\n<h2><strong>C\u00e1c l\u1ef1a ch\u1ecdn s\u00e0ng l\u1ecdc cho JPS l\u00e0 g\u00ec?<\/strong><\/h2>\n<p>V\u00ec ph\u01b0\u01a1ng ph\u00e1p s\u00e0ng l\u1ecdc kh\u00e1c nhau gi\u1eefa m\u1ed7i ng\u01b0\u1eddi n\u00ean vi\u1ec7c th\u1ea3o lu\u1eadn v\u1edbi b\u00e1c s\u0129 v\u1ec1 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p s\u00e0ng l\u1ecdc sau \u0111\u00e2y l\u00e0 h\u1ebft s\u1ee9c quan tr\u1ecdng:<\/p>\n<ul>\n<li>B\u1ea5t k\u1ef3 d\u1ea5u hi\u1ec7u ch\u1ea3y m\u00e1u tr\u1ef1c tr\u00e0ng, thi\u1ebfu m\u00e1u, \u0111au b\u1ee5ng, t\u00e1o b\u00f3n, ti\u00eau ch\u1ea3y ho\u1eb7c thay \u0111\u1ed5i v\u1ec1 t\u00ednh ch\u1ea5t c\u1ee7a ph\u00e2n n\u00ean \u0111\u01b0\u1ee3c \u0111\u01b0a \u0111\u1ebfn b\u00e1c s\u0129 \u0111\u1ec3 \u0111\u00e1nh gi\u00e1.<\/li>\n<li><a href=\"https:\/\/yhoccongdong.com\/thongtin\/noi-soi-dai-trang-colonoscopy\/\" target=\"_blank\" rel=\"noopener\"><strong>N\u1ed9i\u00a0soi \u0111\u1ea1i tr\u00e0ng<\/strong><\/a>\u00a0v\u00e0\u00a0<strong><a href=\"https:\/\/yhoccongdong.com\/thongtin\/noi-soi-da-day-gastroscopy\/\" target=\"_blank\" rel=\"noopener\">n\u1ed9i soi ti\u00eau ho\u00e1 tr\u00ean<\/a>\u00a0<\/strong>n\u00ean \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u1edf tu\u1ed5i 15 ho\u1eb7c s\u1edbm h\u01a1n n\u1ebfu c\u00f3 tri\u1ec7u ch\u1ee9ng.\u00a0N\u1ebfu k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m l\u00e0 b\u00ecnh th\u01b0\u1eddng, ch\u00fang n\u00ean \u0111\u01b0\u1ee3c l\u1eb7p l\u1ea1i sau m\u1ed7i 1 \u0111\u1ebfn 3 n\u0103m, t\u00f9y thu\u1ed9c v\u00e0o s\u1ed1 l\u01b0\u1ee3ng polyp.<\/li>\n<li>Nh\u1eefng ng\u01b0\u1eddi c\u00f3 s\u1ed1 l\u01b0\u1ee3ng l\u1edbn polyp kh\u00f4ng th\u1ec3 c\u1eaft b\u1ecf trong khi n\u1ed9i soi c\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i ph\u1eabu thu\u1eadt \u0111\u1ec3 lo\u1ea1i b\u1ecf m\u1ed9t ph\u1ea7n c\u1ee7a \u0111\u1ea1i tr\u00e0ng ho\u1eb7c d\u1ea1 d\u00e0y.<\/li>\n<li>Nh\u1eefng ng\u01b0\u1eddi b\u1ecb JPS v\u00e0 c\u00f3 \u0111\u1ed9t bi\u1ebfn gen\u00a0<em>SMAD4<\/em>n\u00ean n\u00f3i chuy\u1ec7n v\u1edbi b\u00e1c s\u0129 v\u1ec1 s\u00e0ng l\u1ecdc b\u1ed5 sung cho HHT.<\/li>\n<\/ul>\n<p>Nh\u1eefng h\u01b0\u1edbng d\u1eabn s\u00e0ng l\u1ecdc c\u00f3 th\u1ec3 thay \u0111\u1ed5i theo th\u1eddi gian khi c\u00e1c c\u00f4ng ngh\u1ec7 m\u1edbi ph\u00e1t tri\u1ec3n v\u00e0 hi\u1ec3u bi\u1ebft nhi\u1ec1u h\u01a1n v\u1ec1 JPS. H\u00e3y th\u1ea3o lu\u1eadn v\u1edbi nh\u00f3m ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u1ec1 c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc th\u00edch h\u1ee3p.<\/p>\n<p><em>T\u00ecm hi\u1ec3u th\u00eam th\u00f4ng tin v\u1ec1 <a href=\"http:\/\/www.cancer.net\/node\/24959\" target=\"_blank\" rel=\"noopener\">nh\u1eefng mong \u0111\u1ee3i khi th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m, th\u1ee7 thu\u1eadt v\u00e0 si\u00eau \u00e2m th\u00f4ng th\u01b0\u1eddng<\/a>.<\/em><\/p>\n<h2><strong>Nh\u1eefng c\u00e2u h\u1ecfi c\u1ea7n \u0111\u1eb7t ra cho nh\u00f3m<\/strong> <strong>ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe<\/strong><\/h2>\n<p>N\u1ebfu b\u1ea1n lo l\u1eafng v\u1ec1 nguy c\u01a1 ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng ho\u1eb7c c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c, h\u00e3y n\u00f3i chuy\u1ec7n v\u1edbi nh\u00f3m ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe.\u00a0B\u1ea1n c\u0169ng n\u00ean \u0111i c\u00f9ng m\u1ed9t ng\u01b0\u1eddi kh\u00e1c \u0111\u1ec3 c\u00f3 th\u1ec3 ghi ch\u00e9p nh\u1eefng th\u00f4ng tin c\u1ea7n thi\u1ebft. H\u00e3y c\u00e2n nh\u1eafc h\u1ecfi nh\u00f3m ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe nh\u1eefng c\u00e2u h\u1ecfi sau:<\/p>\n<ul>\n<li>Nguy c\u01a1 x\u1ea3y ra ung th\u01b0 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a c\u1ee7a t\u00f4i l\u00e0 g\u00ec?<\/li>\n<li>T\u1ed5ng c\u1ed9ng t\u00f4i c\u00f3 bao nhi\u00eau polyp \u0111\u1ea1i tr\u00e0ng?<\/li>\n<li>T\u00f4i m\u1eafc lo\u1ea1i polyp \u0111\u1ea1i tr\u00e0ng n\u00e0o?Hai lo\u1ea1i ph\u1ed5 bi\u1ebfn nh\u1ea5t l\u00e0 polyp t\u0103ng s\u1ea3n (l\u00e0 s\u1ef1 t\u0103ng tr\u01b0\u1edfng kh\u00f4ng ung th\u01b0 trong ni\u00eam m\u1ea1c \u0111\u1ea1i tr\u00e0ng) v\u00e0 polyp adenomatous (l\u00e0 s\u1ef1 t\u0103ng tr\u01b0\u1edfng trong ni\u00eam m\u1ea1c \u0111\u1ea1i tr\u00e0ng c\u00f3 th\u1ec3 tr\u1edf th\u00e0nh ung th\u01b0).<\/li>\n<li>T\u00f4i c\u00f3 th\u1ec3 l\u00e0m g\u00ec \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 m\u1eafc ung th\u01b0?<\/li>\n<li>C\u00f3 nh\u1eefng ph\u01b0\u01a1ng ph\u00e1p n\u00e0o gi\u00fap t\u00f4i s\u00e0ng l\u1ecdc ung th\u01b0?<\/li>\n<\/ul>\n<p>N\u1ebfu b\u1ea1n lo l\u1eafng v\u1ec1 ti\u1ec1n s\u1eed gia \u0111\u00ecnh v\u00e0 ngh\u0129 r\u1eb1ng gia \u0111\u00ecnh b\u1ea1n c\u00f3 th\u1ec3 m\u1eafc JPS, h\u00e3y c\u00e2n nh\u1eafc h\u1ecfi nh\u1eefng c\u00e2u h\u1ecfi sau:<\/p>\n<ul>\n<li>Ti\u1ec1n s\u1eed gia \u0111\u00ecnh c\u1ee7a t\u00f4i c\u00f3 l\u00e0m t\u0103ng nguy c\u01a1 ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng ho\u1eb7c c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c c\u1ee7a t\u00f4i kh\u00f4ng?<\/li>\n<li>Ti\u1ec1n s\u1eed gia \u0111\u00ecnh c\u00f3 c\u1ea7n thi\u1ebft trong vi\u1ec7c \u0111\u00e1nh gi\u00e1 nguy c\u01a1 ung th\u01b0 hay kh\u00f4ng?<\/li>\n<li>T\u00f4i c\u00f3 c\u1ea7n tham v\u1ea5n chuy\u00ean gia di truy\u1ec1n kh\u00f4ng?<\/li>\n<li>T\u00f4i c\u00f3 n\u00ean l\u00e0m c\u00e1c <a href=\"https:\/\/yhoccongdong.com\/thongtin\/xet-nghiem-di-truyen-nhung-dieu-can-biet\/\" target=\"_blank\" rel=\"noopener\">x\u00e9t nghi\u1ec7m di truy\u1ec1n<\/a> kh\u00f4ng?<\/li>\n<\/ul>\n<h2><strong>Nh\u1eefng ngu\u1ed3n th\u00f4ng tin li\u00ean quan<\/strong><\/h2>\n<p><a href=\"https:\/\/www.cancer.net\/node\/24897\" target=\"_blank\" rel=\"noopener\"><strong>Di truy\u1ec1n c\u1ee7a ung th\u01b0<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/www.cancer.net\/node\/24895\" target=\"_blank\" rel=\"noopener\"><strong>X\u00e9t nghi\u1ec7m di truy\u1ec1n<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/www.cancer.net\/node\/24907\" target=\"_blank\" rel=\"noopener\"><strong>Nh\u1eefng g\u00ec mong \u0111\u1ee3i khi n\u00f3i chuy\u1ec7n v\u1edbi t\u01b0 v\u1ea5n vi\u00ean di truy\u1ec1n<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/www.cancer.net\/node\/30761\" target=\"_blank\" rel=\"noopener\"><strong>Thu th\u1eadp ti\u1ec1n s\u1eed ung th\u01b0 c\u1ee7a gia \u0111\u00ecnh<\/strong><\/a><\/p>\n<p><a href=\"https:\/\/www.cancer.net\/node\/36141\" target=\"_blank\" rel=\"noopener\"><strong>Chia s\u1ebb k\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m di truy\u1ec1n v\u1edbi gia \u0111\u00ecnh b\u1ea1n<\/strong><\/a><\/p>\n<h2><strong>More Information<\/strong><\/h2>\n<p><a href=\"http:\/\/www.ccalliance.org\" target=\"_blank\" rel=\"noopener\">Colon Cancer Alliance<\/a><\/p>\n<p><a href=\"http:\/\/www.fightcolorectalcancer.org\" target=\"_blank\" rel=\"noopener\">C3: Colorectal Cancer Coalition<\/a><\/p>\n<p><a href=\"http:\/\/www.hcctakesguts.org\" target=\"_blank\" rel=\"noopener\">Hereditary Colon Cancer Takes Guts<\/a><\/p>\n<p><strong>To find a genetic counselor in your area, ask your doctor or visit the following websites:\u00a0<\/strong><\/p>\n<p><a href=\"http:\/\/www.nsgc.org\" target=\"_blank\" rel=\"noopener\">National Society of Genetic Counselors<\/a><\/p>\n<p><a href=\"http:\/\/www.cancer.gov\/cancertopics\/genetics\/directory\" target=\"_blank\" rel=\"noopener\">National Cancer Institute: Cancer Genetics Services Directory<\/a><\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p><a href=\"https:\/\/www.cancer.net\/cancer-types\/juvenile-polyposis-syndrome\">https:\/\/www.cancer.net\/cancer-types\/juvenile-polyposis-syndrome<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>H\u1ed9i ch\u1ee9ng polyp juvenile (JPS) l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a polyp hamartomatous trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n","protected":false},"author":476,"featured_media":8473,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3104,2460],"tags":[3235,3106],"series":[1953],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - 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