{"id":8950,"date":"2021-10-08T17:21:17","date_gmt":"2021-10-08T10:21:17","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/coenzyme-q10-thong-tin-danh-cho-can-bo-y-te\/"},"modified":"2024-04-29T16:58:19","modified_gmt":"2024-04-29T09:58:19","slug":"coenzyme-q10-thong-tin-danh-cho-can-bo-y-te","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/coenzyme-q10-thong-tin-danh-cho-can-bo-y-te\/","title":{"rendered":"Coenzyme Q10 &#8211; Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf"},"content":{"rendered":"<p style=\"text-align: right;\"><em><strong>Bi\u00ean d\u1ecbch: Tr\u1ea7n Nguy\u1ec5n \u0110oan Th\u1ee5c<\/strong><\/em><\/p>\n<p style=\"text-align: right;\"><em><strong>Hi\u1ec7u \u0111\u00ednh: DS. \u0110\u1eb7ng Ho\u00e0i Thu \u2013 B\u1ec7nh vi\u1ec7n Ung B\u01b0\u1edbu H\u00e0 N\u1ed9i <\/strong><\/em><\/p>\n<h2><strong>T\u00ean g\u1ecdi th\u00f4ng th\u01b0\u1eddng<\/strong><\/h2>\n<ul>\n<li>Ubiquinone<\/li>\n<li>Ubidecarenone<\/li>\n<li>Ubiquinol<\/li>\n<li>CoQ<\/li>\n<li>CoQ10<\/li>\n<\/ul>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-39142 aligncenter\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2021\/09\/Coenzym-Q10.jpg\" alt=\"Coenzyme Q10\" width=\"660\" height=\"330\" \/><\/p>\n<h2><strong>Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf<\/strong><\/h2>\n<h3><strong><em>T\u00ean th\u01b0\u01a1ng m\u1ea1i<\/em><\/strong><\/h3>\n<p>UbiQgel \u2122<\/p>\n<h3><strong><em>T\u00ean khoa h\u1ecdc<\/em><\/strong><\/h3>\n<p>2,3 dimetoxy-5 metyl-6-decaprenyl benzoquinon<\/p>\n<h3><strong><em>T\u00f3m t\u1eaft l\u00e2m s\u00e0ng<\/em><\/strong><\/h3>\n<p>Coenzyme Q10 (CoQ10), c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ubiquinone, tham gia v\u00e0o qu\u00e1 tr\u00ecnh h\u00f4 h\u1ea5p t\u1ebf b\u00e0o v\u00e0 s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng. CoQ10 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong t\u1ea5t c\u1ea3 c\u00e1c t\u1ebf b\u00e0o c\u1ee7a con ng\u01b0\u1eddi, v\u00e0 c\u00f3 n\u1ed3ng \u0111\u1ed9 cao \u1edf gan, th\u1eadn, tim v\u00e0 t\u1ee5y. Nh\u1edd t\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a, CoQ10 \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh d\u01b0\u1edbi d\u1ea1ng th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c qu\u1ea3ng c\u00e1o c\u00f3 kh\u1ea3 n\u0103ng ng\u0103n ng\u1eeba c\u00e1c b\u1ec7nh tim m\u1ea1ch, b\u1ec7nh Parkinson, v\u00f4 sinh v\u00e0 ung th\u01b0. C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean chu\u1ed9t cho th\u1ea5y CoQ10 c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a, b\u1ea3o v\u1ec7 th\u1ea7n kinh, v\u00e0 c\u00f3 ti\u1ec1m n\u0103ng l\u00e0m gi\u1ea3m nh\u1eb9 t\u1ed5n th\u01b0\u01a1ng th\u1eadn do x\u1ea1 tr\u1ecb.<\/p>\n<p>K\u1ebft qu\u1ea3 m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u tr\u00ean ng\u01b0\u1eddi cho th\u1ea5y CoQ10 c\u00f3 th\u1ec3 c\u00f3 l\u1ee3i tr\u00ean b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh m\u1ea1ch v\u00e0nh, suy tim sung huy\u1ebft, v\u00e0 gi\u1ea3m nguy c\u01a1 t\u1eed vong do tim m\u1ea1ch. Trong c\u00e1c nghi\u00ean c\u1ee9u kh\u00e1c k\u1ebft h\u1ee3p selen v\u00e0 CoQ10 cho th\u1ea5y hi\u1ec7u qu\u1ea3 \u00a0c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim v\u00e0 gi\u1ea3m \u0111\u00e1ng k\u1ec3 t\u1ef7 l\u1ec7 t\u1eed vong. Tuy nhi\u00ean, m\u1ed9t \u0111\u00e1nh gi\u00e1 h\u1ec7 th\u1ed1ng \u0111\u00e3 k\u1ebft lu\u1eadn r\u1eb1ng c\u00e1c b\u1eb1ng ch\u1ee9ng hi\u1ec7n t\u1ea1i kh\u00f4ng \u1ee7ng h\u1ed9 vi\u1ec7c b\u1ed5 sung CoQ10 th\u01b0\u1eddng quy \u1edf b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh l\u00fd m\u1ea1ch v\u00e0nh.<\/p>\n<p>C\u00e1c quan s\u00e1t tr\u00ean b\u1ec7nh nh\u00e2n d\u00f9ng statin nh\u1eadn th\u1ea5y hi\u1ec7n t\u01b0\u1ee3ng gi\u1ea3m n\u1ed3ng \u0111\u1ed9 CoQ10 trong t\u1ebf b\u00e0o c\u01a1, \u0111i\u1ec1u n\u00e0y g\u1ee3i \u00fd vi\u1ec7c ti\u1ebfn h\u00e0nh c\u00e1c th\u1eed nghi\u1ec7m \u0111\u00e1nh gi\u00e1 hi\u1ec7u qu\u1ea3 c\u1ee7a CoQ10 \u0111\u1ed1i v\u1edbi b\u1ec7nh \u0111au c\u01a1 do statin, tuy nhi\u00ean c\u00e1c d\u1eef li\u1ec7u n\u00e0y v\u1eabn ch\u01b0a th\u1ef1c s\u1ef1 thuy\u1ebft ph\u1ee5c. Vi\u1ec7c b\u1ed5 sung CoQ10 trong th\u1eddi gian ng\u1eafn \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng ch\u1ea1y th\u1eadn nh\u00e2n t\u1ea1o gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc trong chuy\u1ec3n h\u00f3a insulin, nh\u01b0ng n\u1ed3ng \u0111\u1ed9 glucose l\u00fac \u0111\u00f3i, HbA1c hay c\u00e1c ch\u1ec9 s\u1ed1 lipid kh\u00f4ng \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n. M\u1ed9t ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p k\u1ebft lu\u1eadn b\u1eb1ng ch\u1ee9ng v\u1ec1 l\u1ee3i \u00edch c\u1ee7a CoQ10 v\u1edbi b\u1ec7nh th\u1eadn do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf v\u00e0 c\u1ea7n c\u00f3 th\u00eam c\u00e1c nghi\u00ean c\u1ee9u b\u1ed5 sung.<\/p>\n<p>CoQ10 c\u00f3 th\u1ec3 h\u1eefu \u00edch trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p ph\u00f2ng ng\u1eeba ch\u1ee9ng \u0111au n\u1eeda \u0111\u1ea7u. M\u1ed9t nghi\u00ean c\u1ee9u nh\u1ecf cho th\u1ea5y vi\u1ec7c b\u1ed5 sung CoQ10 l\u00e0m gi\u1ea3m t\u1ea7n su\u1ea5t \u0111au n\u1eeda \u0111\u1ea7u, v\u00e0 c\u00e1c d\u1eef li\u1ec7u kh\u00e1c cho th\u1ea5y CoQ10 c\u00f2n gi\u00fap gi\u1ea3m s\u1ed1 ng\u00e0y v\u00e0 th\u1eddi gian \u0111au n\u1eeda \u0111\u1ea7u, tuy nhi\u00ean kh\u00f4ng gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng c\u01a1n v\u00e0 m\u1ee9c \u0111\u1ed9 n\u1eb7ng. Trong m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean, vi\u1ec7c b\u1ed5 sung CoQ10 \u1edf tr\u1ebb em b\u1ecb \u0111au n\u1eeda \u0111\u1ea7u \u0111\u00e3 cho th\u1ea5y kh\u00f4ng \u0111em l\u1ea1i l\u1ee3i \u00edch.<\/p>\n<p>M\u1eb7c d\u00f9 t\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7 th\u1ea7n kinh c\u1ee7a CoQ10 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o trong m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u nh\u1ecf, c\u00e1c nghi\u00ean c\u1ee9u l\u1edbn v\u1edbi thi\u1ebft k\u1ebf t\u1ed1t h\u01a1n kh\u00f4ng ghi nh\u1eadn hi\u1ec7u qu\u1ea3 c\u1ee7a CoQ10 trong b\u1ec7nh Parkinson hay b\u1ec7nh Huntington. Trong c\u00e1c nghi\u00ean c\u1ee9u kh\u00e1c, CoQ10 \u0111\u01b0\u1ee3c ghi nh\u1eadn gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng b\u1ec7nh tr\u1ea7m c\u1ea3m \u1edf b\u1ec7nh nh\u00e2n r\u1ed1i lo\u1ea1n l\u01b0\u1ee1ng c\u1ef1c, nh\u01b0ng s\u1ef1 k\u1ebft h\u1ee3p c\u00e1c ch\u1ea5t ch\u1ed1ng oxy h\u00f3a bao g\u1ed3m CoQ10, vitamin C v\u00e0 E, v\u00e0 axit anpha lipoic kh\u00f4ng \u0111em l\u1ea1i hi\u1ec7u qu\u1ea3 trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Alzheimer.<\/p>\n<figure id=\"attachment_39193\" aria-describedby=\"caption-attachment-39193\" style=\"width: 1980px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" class=\"wp-image-39193 size-full\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2018\/09\/8.jpg\" alt=\"Coenzyme Q10 - Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf\" width=\"1980\" height=\"990\" \/><figcaption id=\"caption-attachment-39193\" class=\"wp-caption-text\">Coenzyme Q10 &#8211; Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf<\/figcaption><\/figure>\n<p>C\u00e1c d\u1eef li\u1ec7u kh\u00e1c g\u1ee3i \u00fd b\u1ed5 sung CoQ10 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9 di \u0111\u1ed9ng c\u1ee7a tinh tr\u00f9ng \u1edf nam gi\u1edbi, \u0111i\u1ec1u h\u00f2a insulin, lipid, c\u00e1c d\u1ea5u \u1ea5n vi\u00eam \u1edf ph\u1ee5 n\u1eef m\u1eafc h\u1ed9i ch\u1ee9ng bu\u1ed3ng tr\u1ee9ng \u0111a nang, v\u00e0 gi\u1ea3m m\u1ec7t m\u1ecfi do g\u1eafng s\u1ee9c; gi\u1ea3m c\u00e1c d\u1ea5u \u1ea5n stress oxi h\u00f3a; c\u0169ng nh\u01b0 c\u00e1c d\u1ea5u \u1ea5n vi\u00eam \u1edf b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh m\u00e3n t\u00ednh. Trong m\u1ed9t nghi\u00ean c\u1ee9u li\u00ean quan \u0111\u1ebfn b\u1ec7nh nh\u00e2n nhi\u1ec5m tr\u00f9ng huy\u1ebft, b\u1ed5 sung CoQ10 trong giai \u0111o\u1ea1n \u0111\u1ea7u c\u00f3 t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c \u0111\u1ebfn c\u00e1c th\u00f4ng s\u1ed1 l\u00e2m s\u00e0ng v\u00e0 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng ty th\u1ec3.<\/p>\n<p>CoQ10 c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u tr\u00ean b\u1ec7nh nh\u00e2n ung th\u01b0. C\u00e1c k\u1ebft qu\u1ea3 b\u01b0\u1edbc \u0111\u1ea7u nghi\u00ean c\u1ee9u t\u00e1c d\u1ee5ng c\u1ee7a CoQ10 trong ki\u1ec3m so\u00e1t ch\u1ee9ng m\u1ec7t m\u1ecfi do ung th\u01b0 hi\u1ec7n kh\u00f4ng \u0111\u1ed3ng nh\u1ea5t. Tr\u00ean c\u00e1c b\u1ec7nh nh\u00e2n \u0111ang \u0111i\u1ec1u tr\u1ecb v\u1edbi tamoxifen, CoQ10 d\u01b0\u1eddng nh\u01b0 c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 c\u00e1c cytokine g\u00e2y vi\u00eam. Tr\u00ean b\u1ec7nh nh\u00e2n ung th\u01b0 bi\u1ec3u m\u00f4 t\u1ebf b\u00e0o gan, n\u1ed3ng \u0111\u1ed9 coenzyme Q10 c\u00f3 t\u01b0\u01a1ng quan thu\u1eadn chi\u1ec1u v\u1edbi kh\u1ea3 n\u0103ng ch\u1ed1ng oxy h\u00f3a v\u00e0 t\u01b0\u01a1ng quan ng\u01b0\u1ee3c chi\u1ec1u v\u1edbi c\u00e1c d\u1ea5u \u1ea5n vi\u00eam h\u1eadu ph\u1eabu. Tuy nhi\u00ean, vi\u1ec7c b\u1ed5 sung ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong \u0111\u00f3 c\u00f3 CoQ10 tr\u01b0\u1edbc v\u00e0 trong \u0111i\u1ec1u tr\u1ecb, c\u00f3 li\u00ean quan \u0111\u1ebfn t\u0103ng nguy c\u01a1 t\u00e1i ph\u00e1t \u1edf b\u1ec7nh nh\u00e2n ung th\u01b0 v\u00fa. V\u00ec v\u1eady, v\u1eabn c\u1ea7n nghi\u00ean c\u1ee9u th\u00eam v\u1ec1 v\u1ea5n \u0111\u1ec1 n\u00e0y..<\/p>\n<p>CoQ10 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t \u0111\u1ed9ng c\u1ee7a warfarin. Do \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a, CoQ10 c\u0169ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a li\u1ec7u ph\u00e1p h\u00f3a tr\u1ecb v\u00e0 x\u1ea1 tr\u1ecb.<\/p>\n<h3><strong><em>M\u1ee5c \u0111\u00edch s\u1eed d\u1ee5ng<\/em><\/strong><\/h3>\n<ul>\n<li>Ung th\u01b0<\/li>\n<li>M\u1ec7t m\u1ecfi<\/li>\n<li>B\u1ec7nh l\u00fd tim m\u1ea1ch<\/li>\n<li>T\u0103ng cholesterol m\u00e1u<\/li>\n<li>B\u1ec7nh Huntington<\/li>\n<li>V\u00f4 sinh<\/li>\n<li>\u0110au n\u1eeda \u0111\u1ea7u<\/li>\n<li>B\u1ec7nh Parkinson<\/li>\n<\/ul>\n<h3><strong><em>C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng<\/em><\/strong><\/h3>\n<p>CoQ10 \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, gi\u00fap \u1ed5n \u0111\u1ecbnh m\u00e0ng t\u1ebf b\u00e0o v\u00e0 l\u00e0 ch\u1ea5t n\u1ed9i sinh duy nh\u1ea5t \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1eeb lipid c\u00f3 ch\u1ee9c n\u0103ng oxy h\u00f3a kh\u1eed \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa. T\u1ea5t c\u1ea3 c\u00e1c t\u1ebf b\u00e0o \u0111\u1ec1u c\u00f3 kh\u1ea3 n\u0103ng t\u1ed5ng h\u1ee3p CoQ10 v\u00e0 kh\u00f4ng c\u00f3 s\u1ef1 t\u00e1i ph\u00e2n b\u1ed1 qua m\u00e1u CoQ10 gi\u1eefa c\u00e1c c\u01a1 quan v\u1edbi nhau. CoQ10 c\u1ea7n thi\u1ebft cho vi\u1ec7c s\u1ea3n xu\u1ea5t adenosine triphosphate (ATP), c\u00f3 vai tr\u00f2 nh\u01b0 m\u1ed9t ch\u1ea5t mang \u0111i\u1ec7n t\u1eed di \u0111\u1ed9ng trong qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111i\u1ec7n t\u1eed c\u1ee7a ty th\u1ec3 x\u1ea3y ra khi h\u00f4 h\u1ea5p v\u00e0 qu\u00e1 tr\u00ecnh phosphoryl h\u00f3a. CoQ10 c\u0169ng c\u00f3 vai tr\u00f2 \u0111i\u1ec1u h\u00f2a tr\u1ef1c ti\u1ebfp trong qu\u00e1 tr\u00ecnh dehydro h\u00f3a succinyl v\u00e0 NADH. CoQ10 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 kh\u1ea3 n\u0103ng kh\u1eed s\u1ea1ch c\u00e1c g\u1ed1c t\u1ef1 do \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi qu\u00e1 tr\u00ecnh peroxy h\u00f3a lipid, ng\u0103n ng\u1eeba s\u1ef1 bi\u1ebfn d\u1ea1ng ty th\u1ec3 c\u0169ng nh\u01b0 gi\u00fap duy tr\u00ec t\u00ednh to\u00e0n v\u1eb9n c\u1ee7a c\u00e1c k\u00eanh ion canxi \u1edf c\u01a1 tim trong c\u00e1c \u0111\u1ee3t thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9. CoQ10 c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng \u1ed5n \u0111\u1ecbnh m\u00e0ng t\u1ebf b\u00e0o v\u00e0 ng\u0103n ng\u1eeba s\u1ef1 tho\u00e1i h\u00f3a c\u1ee7a c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ea7n thi\u1ebft cho qu\u00e1 tr\u00ecnh t\u00e1i t\u1ed5ng h\u1ee3p ATP, \u0111\u1ed3ng th\u1eddi ng\u0103n ch\u1eb7n c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c v\u00e0 s\u1ef1 bi\u1ec7t h\u00f3a c\u1ee7a t\u1ebf b\u00e0o h\u1ee7y x\u01b0\u01a1ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf stress oxy h\u00f3a. M\u1ed9t trong nh\u1eefng c\u01a1 ch\u1ebf c\u0103n b\u1ea3n c\u1ee7a t\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7 th\u1ea7n kinh b\u1edfi CoQ10 li\u00ean quan \u0111\u1ebfn vi\u1ec7c \u1ee9c ch\u1ebf t\u1ebf b\u00e0o th\u1ea7n kinh \u0111\u1ec7m microglia trong b\u1ec7nh \u0111\u1ed9ng kinh nh\u1eb9 do pentylenetetrazol trong nghi\u00ean c\u1ee9u \u1edf chu\u1ed9t .<\/p>\n<p>C\u00e1c nghi\u00ean c\u1ee9u ti\u1ec1n l\u00e2m s\u00e0ng kh\u00e1c cho th\u1ea5y CoQ10 c\u00f3 th\u1ec3 ng\u0103n ng\u1eeba s\u1ef1 gi\u1ea3m n\u1ed3ng \u0111\u1ed9 protein v\u1eadn chuy\u1ec3n glucose-4 trong t\u1ebf b\u00e0o m\u1ee1 do simvastatin g\u00e2y ra, m\u1ed9t trong nh\u1eefng nguy c\u01a1 d\u1eabn \u0111\u1ebfn kh\u1edfi ph\u00e1t ti\u1ec3u \u0111\u01b0\u1eddng \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng statin. CoQ10 c\u0169ng l\u00e0m gi\u1ea3m qu\u00e1 tr\u00ecnh ch\u1ebft theo chu tr\u00ecnh do n\u1ed3ng \u0111\u1ed9 glucose cao v\u00e0 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng c\u1ee7a c\u00e1c t\u1ebf b\u00e0o n\u1ed9i m\u00f4 nguy\u00ean s\u01a1 b\u1eb1ng c\u00e1ch t\u0103ng t\u1ed5ng h\u1ee3p nitric oxid n\u1ed9i m\u00f4 v\u00e0 heme oxygenase th\u00f4ng qua con \u0111\u01b0\u1eddng protein kinase ho\u1ea1t h\u00f3a b\u1edfi AMP. Trong nghi\u00ean c\u1ee9u tr\u00ean m\u00f4 h\u00ecnh chu\u1ed9t, CoQ10 gi\u00fap b\u1ea3o v\u1ec7 tinh ho\u00e0n kh\u1ecfi \u0111\u1ed9c t\u00ednh do doxorubicin g\u00e2y ra b\u1eb1ng c\u00e1ch c\u1ea3i thi\u1ec7n stress oxy h\u00f3a v\u00e0 gi\u1ea3m s\u1ef1 ch\u1ebft theo chu tr\u00ecnh b\u1eb1ng c\u00e1ch \u0111i\u1ec1u h\u00f2a P-glycoprotein.<\/p>\n<h3><strong><em>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/em><\/strong><\/h3>\n<p>Trong nghi\u00ean c\u1ee9u tr\u00ean m\u00f4 h\u00ecnh chu\u1ed9t v\u1ec1 ung th\u01b0 ph\u1ed5i kh\u00f4ng t\u1ebf b\u00e0o nh\u1ecf, vi\u1ec7c u\u1ed1ng ubiquinone d\u01b0\u1eddng nh\u01b0 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a x\u1ea1 tr\u1ecb.<\/p>\n<h3><strong><em>T\u00e1c d\u1ee5ng ph\u1ee5<\/em><\/strong><\/h3>\n<p>Kh\u00f4ng th\u01b0\u1eddng xuy\u00ean: Bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y v\u00e0 gi\u1ea3m c\u1ea3m gi\u00e1c ngon mi\u1ec7ng.<\/p>\n<h3><strong><em>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/em><\/strong><\/h3>\n<ul>\n<li><strong>Thu\u1ed1c \u1ee9c ch\u1ebf HMG-CoA reductase<\/strong>: N\u1ed3ng \u0111\u1ed9 CoQ10 n\u1ed9i sinh c\u00f3 th\u1ec3 \u00a0gi\u1ea3m do lovastatin, atorvastatin v\u00e0 simvastatin. Enzym HMG-CoA reductase ch\u1ecbu tr\u00e1ch nhi\u1ec7m x\u00fac t\u00e1c qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i acetyl CoA th\u00e0nh cholesterol v\u00e0 t\u1ed5ng h\u1ee3p CoQ10.<\/li>\n<li><strong>Warfarin:<\/strong> CoQ10 c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 nh\u01b0 vitamin K v\u00e0 c\u00f3 th\u1ec3 \u0111\u1ed1i kh\u00e1ng v\u1edbi t\u00e1c d\u1ee5ng c\u1ee7a warfarin. Tuy nhi\u00ean, CoQ10 \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o l\u00e0 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u khi s\u1eed d\u1ee5ng v\u1edbi warfarin.<\/li>\n<li><strong>Theophylline:<\/strong> CoQ10 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh thanh th\u1ea3i theophylline, c\u00f3 th\u1ec3 g\u00e2y n\u00f4n dai d\u1eb3ng, r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 co gi\u1eadt kh\u00f3 ki\u1ec3m so\u00e1t.<\/li>\n<\/ul>\n<pre>Xem th\u00eam b\u00e0i vi\u1ebft <a href=\"https:\/\/yhoccongdong.com\/thongtin\/coenzyme-q10-thong-tin-danh-cho-benh-nhan-va-nguoi-nha\/\" target=\"_blank\" rel=\"noopener\"><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;Coenzyme Q10 - Th\u00f4ng tin d\u00e0nh cho b\u1ec7nh nh\u00e2n v\u00e0 ng\u01b0\u1eddi nh\u00e0&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:513,&quot;3&quot;:{&quot;1&quot;:0},&quot;12&quot;:0}\">Coenzyme Q10 - Th\u00f4ng tin d\u00e0nh cho b\u1ec7nh nh\u00e2n v\u00e0 ng\u01b0\u1eddi nh\u00e0<\/span><\/a><\/pre>\n<h2><strong>T\u00e0i li\u1ec7u tham kh\u1ea3o\u00a0 <\/strong><\/h2>\n<p><a href=\"https:\/\/www.mskcc.org\/cancer-care\/integrative-medicine\/herbs\/coenzyme-q10\" target=\"_blank\" rel=\"noopener\">Coenzyme Q10<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Coenzyme Q10 (CoQ10), c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ubiquinone, tham gia v\u00e0o qu\u00e1 tr\u00ecnh h\u00f4 h\u1ea5p t\u1ebf b\u00e0o v\u00e0 s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng. CoQ10 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong t\u1ea5t c\u1ea3 c\u00e1c t\u1ebf b\u00e0o c\u1ee7a con ng\u01b0\u1eddi, v\u00e0 c\u00f3 n\u1ed3ng \u0111\u1ed9 cao \u1edf gan, th\u1eadn, tim v\u00e0 t\u1ee5y.<\/p>\n","protected":false},"author":580,"featured_media":8951,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3797],"tags":[3470,2475,3216],"series":[2174],"coauthors":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Coenzyme Q10 - Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf - D\u1ef1 \u00e1n Ung Th\u01b0<\/title>\n<meta name=\"description\" content=\"Coenzyme Q10 - Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf - D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/ung-thu\/coenzyme-q10-thong-tin-danh-cho-can-bo-y-te\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Coenzyme Q10 - 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