{"id":9085,"date":"2022-03-20T09:16:24","date_gmt":"2022-03-20T02:16:24","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/nghe-thong-tin-danh-cho-can-bo-y-te\/"},"modified":"2024-10-17T20:05:06","modified_gmt":"2024-10-17T13:05:06","slug":"nghe-thong-tin-danh-cho-can-bo-y-te","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/nghe-thong-tin-danh-cho-can-bo-y-te\/","title":{"rendered":"Ngh\u1ec7 – Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf"},"content":{"rendered":"

Bi\u00ean d\u1ecbch: Nguy\u1ec5n Th\u1ecb Y\u1ebfn Ninh, Ho\u00e0ng Thu H\u00e0<\/em><\/strong><\/p>\n

\"Ngh\u1ec7
Ngh\u1ec7 – Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf<\/figcaption><\/figure>\n

T\u01b0\u01a1ng t\u00e1c ngh\u1ec7 – thu\u1ed1c<\/b><\/h2>\n

Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u\/ thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u<\/b><\/h3>\n

C\u00e1c nghi\u00ean c\u1ee9u ti\u1ec1n l\u00e2m s\u00e0ng v\u00e0 m\u1ed9t b\u00e1o c\u00e1o tr\u01b0\u1eddng h\u1ee3p g\u1ee3i \u00fd r\u1eb1ng ngh\u1ec7 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u<\/a>.<\/span><\/p>\n

Camptothecin<\/b><\/h3>\n

Ngh\u1ec7 \u1ee9c ch\u1ebf s\u1ef1 ch\u1ebft t\u1ebf b\u00e0o theo ch\u01b0\u01a1ng tr\u00ecnh c\u1ee7a c\u00e1c d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0 v\u00fa do camptothecin g\u00e2y ra, trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn.<\/span><\/p>\n

Mechlorethamine<\/b><\/h3>\n

Ngh\u1ec7 \u1ee9c ch\u1ebf s\u1ef1 ch\u1ebft t\u1ebf b\u00e0o theo ch\u01b0\u01a1ng tr\u00ecnh c\u1ee7a c\u00e1c d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0 v\u00fa trong \u1ed1ng nghi\u1ec7m, do Mechlorethamine g\u00e2y ra.<\/span><\/p>\n

Paclitaxel<\/b><\/h3>\n

M\u1ed9t b\u00e1o c\u00e1o tr\u01b0\u1eddng h\u1ee3p g\u1ea7n \u0111\u00e2y: M<\/span>\u1ed9t b\u1ec7nh nh\u00e2n ung th\u01b0 ph\u1ed5i c\u00f3 gan b\u1ecb \u0111\u1ed9c trong khi \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb t\u00edch c\u1ef1c b\u1eb1ng paclitaxel. M\u1eb7c d\u1ea7u \u00f4ng \u1ea5y u\u1ed1ng nhi\u1ec1u lo\u1ea1i th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng, m\u1ed9t trong s\u1ed1 \u0111\u00f3 b\u1ecb h\u1ecfng, ngh\u1ec7 \u0111\u01b0\u1ee3c cho l\u00e0 m\u1ed9t trong s\u1ed1 c\u00e1c nguy\u00ean nh\u00e2n r\u1ea5t c\u00f3 th\u1ec3 g\u00e2y ra b\u1ec7nh l\u00fd \u0111\u00f3.<\/span><\/p>\n

Doxorubicin<\/b><\/h3>\n

Ngh\u1ec7 \u1ee9c ch\u1ebf s\u1ef1 ch\u1ebft t\u1ebf b\u00e0o theo ch\u01b0\u01a1ng tr\u00ecnh c\u1ee7a c\u00e1c d\u00f2ng t\u1ebf b\u00e0o ung th\u01b0 v\u00fa do doxorubicin g\u00e2y ra trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Cyclophosphamide<\/b><\/h3>\n

Ngh\u1ec7 trong th\u1ee9c \u0103n \u1ee9c ch\u1ebf s\u1ef1 tho\u00e1i lui c\u1ee7a kh\u1ed1i u do cyclophosphamide g\u00e2y ra, trong c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt. <\/span>S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Norfloxacin<\/b><\/h3>\n

\u0110i\u1ec1u tr\u1ecb s\u01a1 b\u1ed9 (s\u1ef1 ph\u00f2ng tr\u1ecb – pretratment) b\u1eb1ng curcumin d\u1eabn \u0111\u1ebfn t\u0103ng th\u1eddi gian b\u00e1n th\u1ea3i lo\u1ea1i tr\u1eeb trong plasma, do v\u1eady l\u00e0m gi\u1ea3m li\u1ec1u c\u1ee7a norfloxacin trong m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt.<\/span><\/p>\n

Amphotericin B<\/b><\/h3>\n

Curcumin l\u00e0m t\u0103ng hi\u1ec7u qu\u1ea3 v\u00e0 l\u00e0m gi\u1ea3m \u0111\u1ed9c t\u00ednh c\u1ee7a amphotericin B trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

C\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1eb1ng enzyme CYP3A4<\/b><\/h3>\n

Curcumin \u1ee9c ch\u1ebf enzyme cytochrome 3A4, l\u00e0m thay \u0111\u1ed5i qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a c\u1ee7a m\u1ed9t s\u1ed1 thu\u1ed1c k\u00ea \u0111\u01a1n. Nh\u01b0ng theo d\u1eef li\u1ec7u \u0111ang m\u00e2u thu\u1eabn th\u00ec s\u1eed d\u1ee5ng curcumin trong ng\u1eafn h\u1ea1n kh\u00f4ng d\u1eabn \u0111\u1ebfn s\u1ef1 t\u01b0\u01a1ng t\u00e1c li\u00ean quan l\u00e2m s\u00e0ng \u1edf nh\u1eefng t\u00ecnh nguy\u1ec7n vi\u00ean kh\u1ecfe m\u1ea1nh.<\/span><\/p>\n

C\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1eb1ng enzyme CYP1A2<\/b><\/h3>\n

Curcumin \u1ee9c ch\u1ebf enzym cytochrome 1A2, \u1ea3nh h\u01b0\u1edfng t\u1edbi qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a c\u00e1c thu\u1ed1c k\u00ea \u0111\u01a1n n\u00e0o \u0111\u00f3, trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn.<\/span><\/p>\n

C\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1eb1ng enzyme CYP2A6<\/b><\/h3>\n

Curcumin t\u0103ng c\u01b0\u1eddng enzyme cytochrome 2A6 v\u00e0 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng t\u1edbi qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a c\u1ee7a c\u00e1c thu\u1ed1c k\u00ea \u0111\u01a1n n\u00e0o \u0111\u00f3. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u01a1c bi\u1ebft.<\/span><\/p>\n

C\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1eb1ng enzyme CYP2D6<\/b><\/h3>\n

Curcumin \u1ee9c ch\u1ebf ho\u1ea1t t\u00ednh c\u1ee7a cytochrome 2D6 v\u00e0 c\u00f3 ti\u1ec1m n\u0103ng t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1eb1ng CYP2D6. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Celiprolol and Midazolam<\/b><\/h3>\n

Curcumin \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 l\u00e0m gi\u1ea3m \u0111i\u1ec1u h\u00f2a c\u00e1c m\u1ee9c P-gp trong ru\u1ed9t, do v\u1eady l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a celiprolol v\u00e0 midazolam trong m\u00f4 h\u00ecnh chu\u1ed9t. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Verapamil<\/b><\/h3>\n

Curcumin \u1ee9c ch\u1ebf s\u1ef1 b\u1ed9c l\u1ed9 v\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a P-gp trong ru\u1ed9t, do v\u1eady l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a verapamil trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn.<\/span><\/p>\n

Tacrolimus<\/b><\/h3>\n

\u0110i\u1ec1u tr\u1ecb s\u01a1 b\u1ed9 b\u1eb1ng ngh\u1ec7 l\u00e0m t\u0103ng m\u1ee9c tacrolimus trong m\u00e1u trong m\u00f4 h\u00ecnh chu\u1ed9t. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Acetaminophen<\/b><\/h3>\n

\u1ea2nh h\u01b0\u1edfng \u0111\u1ed9c t\u1ebf b\u00e0o c\u1ee7a curcumin t\u0103ng \u0111\u00e1ng k\u1ec3 khi c\u00f3 m\u1eb7t acetaminophen trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Ibuprofen<\/b><\/h3>\n

\u1ea2nh h\u01b0\u1edfng \u0111\u1ed9c t\u1ebf b\u00e0o c\u1ee7a curcumin t\u0103ng \u0111\u00e1ng k\u1ec3 khi c\u00f3 m\u1eb7t ibuprofen trong \u1ed1ng nghi\u1ec7m. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

Aspirin<\/b><\/h3>\n

\u1ea2nh h\u01b0\u1edfng \u0111\u1ed9c t\u1ebf b\u00e0o c\u1ee7a curcumin t\u0103ng \u0111\u00e1ng k\u1ec3 khi c\u00f3 m\u1eb7t aspirin. S\u1ef1 li\u00ean quan l\u00e2m s\u00e0ng ch\u01b0a \u0111\u01b0\u1ee3c bi\u1ebft.<\/span><\/p>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n

https:\/\/www.mskcc.org\/cancer-care\/integrative-medicine\/herbs\/turmeric<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ho\u1ea1t ch\u1ea5t c\u00f3 trong ngh\u1ec7 l\u00e0 curcumin (curcumin l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng oxy h\u00f3a m\u1ea1nh). Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a c\u00f3 t\u00e1c d\u1ee5ng b\u1ea3o v\u1ec7 t\u1ebf b\u00e0o c\u1ee7a b\u1ea1n kh\u1ecfi b\u1ecb h\u01b0 h\u1ea1i.<\/p>\n","protected":false},"author":548,"featured_media":9086,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3797],"tags":[3532,2475,3452],"series":[2174],"coauthors":[1189],"acf":[],"yoast_head":"\nNgh\u1ec7 - Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf - D\u1ef1 \u00e1n Ung Th\u01b0<\/title>\n<meta name=\"description\" content=\"Ngh\u1ec7 - Th\u00f4ng tin d\u00e0nh cho c\u00e1n b\u1ed9 y t\u1ebf - D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/ung-thu\/nghe-thong-tin-danh-cho-can-bo-y-te\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ngh\u1ec7 - 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