{"id":9239,"date":"2022-05-20T04:55:27","date_gmt":"2022-05-19T21:55:27","guid":{"rendered":"https:\/\/yhoccongdong.org\/ung-thu\/thong-tin-chung-ve-trastuzumab\/"},"modified":"2024-10-17T20:09:49","modified_gmt":"2024-10-17T13:09:49","slug":"thong-tin-chung-ve-trastuzumab","status":"publish","type":"post","link":"https:\/\/yhoccongdong.com\/ung-thu\/thong-tin-chung-ve-trastuzumab\/","title":{"rendered":"Th\u00f4ng tin chung v\u1ec1 Trastuzumab"},"content":{"rendered":"<p style=\"text-align: right;\"><em><strong>Bi\u00ean d\u1ecbch: Ho\u00e0ng Thu H\u00e0<\/strong><\/em><\/p>\n<p style=\"text-align: right;\"><em><strong>Hi\u1ec7u \u0111\u00ednh: Ph\u00f9ng Th\u1ecb Huy\u1ec1n, Nguy\u1ec5n V\u0103n T\u00f9ng, \u0110\u1eb7ng Ti\u1ebfn Giang<\/strong><\/em><\/p>\n<h2><strong>Trastuzumab l\u00e0 g\u00ec?<\/strong><\/h2>\n<p>Trastuzumab l\u00e0 thu\u1ed1c s\u1eed d\u1ee5ng trong <a href=\"https:\/\/yhoccongdong.com\/thongtin\/hieu-ve-lieu-phap-nham-dich\/\" target=\"_blank\" rel=\"noopener\">li\u1ec7u ph\u00e1p \u0111\u00edch<\/a> (li\u1ec7u ph\u00e1p sinh h\u1ecdc). C\u00e1c li\u1ec7u ph\u00e1p \u0111\u00edch ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 lan t\u1ecfa c\u1ee7a ung th\u01b0. Ch\u00fang nh\u1eafm \u0111\u1ebfn v\u00e0 can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh trong c\u00e1c t\u1ebf b\u00e0o gi\u00fap ung th\u01b0 ph\u00e1t tri\u1ec3n.<\/p>\n<h2><strong>Thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>C\u00e1c li\u1ec7u ph\u00e1p \u0111\u00edch ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 lan tr\u00e0n c\u1ee7a ung th\u01b0. Ch\u00fang nh\u1eafm \u0111\u1ebfn v\u00e0 can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh trong c\u00e1c t\u1ebf b\u00e0o gi\u00fap ung th\u01b0 ph\u00e1t tri\u1ec3n.<\/p>\n<p>M\u1ed9t s\u1ed1 t\u1ebf b\u00e0o ung th\u01b0 v\u00fa c\u00f3 m\u1ee9c protein \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 HER2 tr\u00ean b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o cao h\u01a1n m\u1ee9c b\u00ecnh th\u01b0\u1eddng. Nh\u1eefng protein n\u00e0y tham gia th\u00fac \u0111\u1ea9y t\u1ebf b\u00e0o ung th\u01b0 t\u0103ng tr\u01b0\u1edfng. Ch\u1eebng m\u1ed9t trong n\u0103m (20%) ung th\u01b0 v\u00fa x\u00e2m l\u1ea5n (ung th\u01b0 v\u00fa c\u00f3 ti\u1ec1m n\u0103ng lan t\u1edbi c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3) c\u00f3 protein n\u00e0y v\u00e0 \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 d\u01b0\u01a1ng t\u00ednh v\u1edbi HER2.<\/p>\n<p>Trastuzumab l\u00e0m vi\u1ec7c b\u1eb1ng c\u00e1ch t\u1ef1 \u0111\u00ednh v\u1edbi c\u00e1c protein HER2 n\u00ean c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 kh\u00f4ng \u0111\u01b0\u1ee3c k\u00edch th\u00edch \u0111\u1ec3 ph\u00e1t tri\u1ec3n n\u1eefa. Thu\u1ed1c c\u0169ng gi\u00fap h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 ph\u00e1 h\u1ee7y t\u1ebf b\u00e0o ung th\u01b0 v\u00fa.<\/p>\n<h2><strong>Khi n\u00e0o ch\u1ec9 \u0111\u1ecbnh trastuzumab?<\/strong><\/h2>\n<p>Ch\u1ec9 nh\u1eefng ng\u01b0\u1eddi ung th\u01b0 v\u00fa d\u01b0\u01a1ng t\u00ednh v\u1edbi HER2 m\u1edbi h\u01b0\u1edfng l\u1ee3i t\u1eeb trastuzumab. N\u1ebfu ung th\u01b0 v\u00fa c\u1ee7a b\u1ea1n \u00e2m t\u00ednh v\u1edbi HER2, th\u00ec trastuzumab kh\u00f4ng mang l\u1ea1i l\u1ee3i \u00edch g\u00ec cho b\u1ea1n.<\/p>\n<p>C\u00f3 nhi\u1ec1u x\u00e9t nghi\u1ec7m \u0111\u1ec3 \u0111o m\u1ee9c \u0111\u1ed9 HER2 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean m\u00f4 v\u00fa l\u1ea5y ra trong khi <a href=\"https:\/\/yhoccongdong.com\/thongtin\/sinh-thiet-biopsy\/\" target=\"_blank\" rel=\"noopener\">sinh thi\u1ebft<\/a> ho\u1eb7c ph\u1eabu thu\u1eadt.<\/p>\n<p>X\u00e9t nghi\u1ec7m HER2 th\u00f4ng th\u01b0\u1eddng \u0111\u01b0\u1ee3c l\u00e0m tr\u00ean ung th\u01b0 v\u00fa x\u00e2m l\u1ea5n, n\u00ean nhi\u1ec1u kh\u1ea3 n\u0103ng kh\u00f4ng \u0111\u01b0\u1ee3c \u0111\u1ec1 c\u1eadp \u0111\u1ebfn n\u1ebfu b\u1ea1n m\u1eafc ung th\u01b0 v\u00fa giai \u0111o\u1ea1n s\u1edbm \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 <a href=\"https:\/\/yhoccongdong.com\/thongtin\/ung-thu-bieu-mo-ong-tuyen-vu-tai-cho\/\" target=\"_blank\" rel=\"noopener\">carcinoma \u1ed1ng tuy\u1ebfn v\u00fa t\u1ea1i ch\u1ed7 (DCIS)<\/a>.<\/p>\n<p>Trastuzumab c\u00f3 th\u1ec3 kh\u00f4ng ph\u00f9 h\u1ee3p cho nh\u1eefng ng\u01b0\u1eddi c\u00f3 v\u1ea5n \u0111\u1ec1 tim m\u1ea1ch ho\u1eb7c huy\u1ebft \u00e1p cao kh\u00f4ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t t\u1ed1t. N\u1ebfu ung th\u01b0 v\u00fa c\u1ee7a b\u1ea1n l\u00e0 d\u01b0\u01a1ng t\u00ednh v\u1edbi HER2 v\u00e0 b\u1ea1n c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 tim, b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb th\u01b0\u1eddng b\u1ed1 tr\u00ed c\u00e1c x\u00e9t nghi\u1ec7m b\u1ed5 sung \u0111\u1ec3 ki\u1ec3m ra ch\u1ee9c n\u0103ng tim c\u1ee7a b\u1ea1n.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\" wp-image-41011 aligncenter\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2022\/05\/thong-tin-chung-ve-trastuzumab-1-300x227-1.png\" alt=\"\" width=\"599\" height=\"453\" \/><\/p>\n<h2><strong>Khi n\u00e0o trastuzumab \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh?<\/strong><\/h2>\n<h3><strong>Ung th\u01b0 v\u00fa nguy\u00ean ph\u00e1t<\/strong><\/h3>\n<p>Trastuzumab th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng nh\u01b0 l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa nguy\u00ean ph\u00e1t (ung th\u01b0 v\u00fa ch\u01b0a lan qu\u00e1 v\u00fa ho\u1eb7c t\u1edbi c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft d\u01b0\u1edbi c\u00e1nh tay).<\/p>\n<h4><strong>Tr\u01b0\u1edbc ph\u1eabu thu\u1eadt<\/strong><\/h4>\n<p>\u0110\u00f4i khi trastuzumab \u0111\u01b0\u1ee3c d\u00f9ng tr\u01b0\u1edbc ph\u1eabu thu\u1eadt v\u00e0 \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3 ho\u1eb7c li\u1ec7u ph\u00e1p ban \u0111\u1ea7u. N\u00f3 c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 l\u00e0m ch\u1eadm s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ung th\u01b0 v\u00fa \u0111\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng lan t\u1edbi c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3, ho\u1eb7c \u0111\u1ec3 l\u00e0m gi\u00fap co kh\u1ed1i u ung th\u01b0 v\u00fa l\u1edbn tr\u01b0\u1edbc ph\u1eabu thu\u1eadt. Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng v\u1edbi h\u00f3a tr\u1ecb v\u00e0 \u0111\u00f4i khi v\u1edbi m\u1ed9t thu\u1ed1c kh\u00e1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 <a href=\"https:\/\/yhoccongdong.com\/thongtin\/thong-tin-chung-ve-pertuzumab-perjeta\/\" target=\"_blank\" rel=\"noopener\">pertuzumab (Perjeta)<\/a>.<\/p>\n<p>B\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb s\u1ebd gi\u1ea3i th\u00edch l\u00fd do khuy\u1ebfn ngh\u1ecb cho m\u1ed7i lo\u1ea1i \u0111i\u1ec1u tr\u1ecb v\u00e0 khi n\u00e0o thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h4><strong>Sau ph\u1eabu thu\u1eadt<\/strong><\/h4>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh sau ph\u1eabu thu\u1eadt \u0111\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng ung th\u01b0 v\u00fa quay tr\u1edf l\u1ea1i ho\u1eb7c lan t\u1edbi c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3, v\u00e0 \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 \u0111i\u1ec1u tr\u1ecb b\u1ed5 tr\u1ee3. Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh c\u00f9ng v\u1edbi ho\u1eb7c sau h\u00f3a tr\u1ecb v\u00e0 \u0111\u00f4i khi c\u00f9ng v\u1edbi pertuzumab.<\/p>\n<h3><strong>Ung th\u01b0 v\u00fa t\u00e1i ph\u00e1t<\/strong><\/h3>\n<p>Trastuzumab c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa quay tr\u1edf l\u1ea1i \u1edf ng\u1ef1c, v\u00fa ho\u1eb7c da g\u1ea7n v\u1edbi v\u1ecb tr\u00ed ban \u0111\u1ea7u ho\u1eb7c \u1edf v\u1ebft s\u1eb9o (\u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u00e1i ph\u00e1t t\u1ea1i ch\u1ed7).<\/p>\n<p>Trastuzumab c\u0169ng c\u00f3 th\u1ec3 d\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa th\u1ee9 ph\u00e1t, l\u00e0 khi c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 v\u00fa lan t\u1eeb v\u00fa t\u1edbi c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3 nh\u01b0 l\u00e0 x\u01b0\u01a1ng, ph\u1ed5i, gan ho\u1eb7c n\u00e3o.<\/p>\n<p><img decoding=\"async\" class=\"wp-image-41012 aligncenter\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2022\/05\/thong-tin-chung-ve-trastuzumab-2-300x195-1.png\" alt=\"\" width=\"600\" height=\"390\" \/><\/p>\n<h2><strong>Trastuzumab \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/h2>\n<p>Trastuzumab c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c d\u00f9ng d\u01b0\u1edbi d\u1ea1ng truy\u1ec1n t\u0129nh m\u1ea1ch \u1edf c\u00e1nh tay ho\u1eb7c b\u00e0n tay.<\/p>\n<p>Thu\u1ed1c c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ti\u00eam v\u00e0o m\u00f4 m\u1ee1 d\u01b0\u1edbi da (ti\u00eam d\u01b0\u1edbi da) \u1edf \u0111\u00f9i b\u1ea1n.<\/p>\n<p>Trastuzumab \u0111\u01b0\u1ee3c d\u00f9ng ph\u1ed5 bi\u1ebfn nh\u1ea5t m\u1ed7i ba tu\u1ea7n m\u1ed9t l\u1ea7n. M\u1ed9t s\u1ed1 ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh h\u00e0ng tu\u1ea7n. B\u1ea1n th\u01b0\u1eddng s\u1ebd \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb nh\u01b0 l\u00e0 b\u1ec7nh nh\u00e2n ngo\u1ea1i tr\u00fa t\u1ea1i b\u1ec7nh vi\u1ec7n, m\u1eb7c d\u1ea7u m\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb t\u1ea1i nh\u00e0.<\/p>\n<p>Trastuzumab th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh v\u1edbi h\u00f3a tr\u1ecb do \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng. Thu\u1ed1c c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh c\u00f9ng v\u1edbi c\u00e1c \u0111i\u1ec1u tr\u1ecb kh\u00e1c nh\u01b0 x\u1ea1 tr\u1ecb, li\u1ec7u ph\u00e1p n\u1ed9i ti\u1ebft v\u00e0 li\u1ec7u ph\u00e1p sinh h\u1ecdc kh\u00e1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 pertuzumab (Perjeta).<\/p>\n<h3><strong>Truy\u1ec1n t\u0129nh m\u1ea1ch<\/strong><\/h3>\n<p>L\u1ea7n truy\u1ec1n \u0111\u1ea7u ti\u00ean th\u01b0\u1eddng di\u1ec5n ra trong m\u1ed9t gi\u1edd r\u01b0\u1ee1i. B\u1ea1n s\u1ebd \u0111\u01b0\u1ee3c y\u00eau c\u1ea7u n\u1eb1m vi\u1ec7n trong v\u00e0i gi\u1edd sau \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o b\u1ea1n kh\u00f4ng c\u1ea3m th\u1ea5y m\u1ec7t tr\u01b0\u1edbc khi ra v\u1ec1. N\u1ebfu kh\u00f4ng c\u00f3 v\u1ea5n \u0111\u1ec1 g\u00ec, c\u00e1c li\u1ec1u sau c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c truy\u1ec1n trong 30 ph\u00fat v\u00e0 b\u1ea1n s\u1ebd ch\u1ec9 c\u1ea7n \u1edf vi\u1ec7n trong m\u1ed9t hai ti\u1ebfng sau \u0111\u00f3.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u01b0a qua m\u1ed9t \u1ed1ng lu\u1ed3n v\u00e0o ven m\u1ed7i l\u1ea7n truy\u1ec1n, ho\u1eb7c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u01b0a qua m\u1ed9t d\u1ee5ng c\u1ee5 n\u1eb1m y\u00ean \u1edf v\u1ecb tr\u00ed trong su\u1ed1t li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>D\u1ea1ng ti\u00eam<\/h3>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c ti\u00eam trong hai t\u1edbi n\u0103m ph\u00fat. C\u00e1c l\u1ea7n ti\u00eam \u0111\u01b0\u1ee3c ti\u00eam l\u1ea7n l\u01b0\u1ee3t v\u00e0o \u0111\u00f9i ph\u1ea3i v\u00e0 tr\u00e1i. B\u1ea1n s\u1ebd \u0111\u01b0\u1ee3c y\u00eau c\u1ea7u n\u1eb1m vi\u1ec7n trong m\u1ed9t v\u00e0i ti\u1ebfng sau l\u1ea7n ti\u00eam \u0111\u1ea7u ti\u00ean \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o b\u1ea1n kh\u00f4ng th\u1ea5y m\u1ec7t tr\u01b0\u1edbc khi ra v\u1ec1. N\u1ebfu kh\u00f4ng c\u00f3 v\u1ea5n \u0111\u1ec1 g\u00ec th\u00ec b\u1ea1n s\u1ebd kh\u00f4ng c\u1ea7n n\u1eb1m l\u1ea1i l\u00e2u sau c\u00e1c l\u1ea7n ti\u00eam sau.<\/p>\n<p>N\u1ebfu b\u1ea1n \u0111\u00e3 truy\u1ec1n t\u0129nh m\u1ea1ch trastuzumab th\u00ec b\u1ea1n c\u00f3 th\u1ec3 chuy\u1ec3n sang ti\u00eam d\u01b0\u1edbi da.<\/p>\n<p>C\u00e1c thu\u1ed1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng sinh h\u1ecdc v\u1edbi trastuzumab nh\u01b0 l\u00e0 Herzuma, Kanjinti v\u00e0 Ontruzant kh\u00f4ng c\u00f3 \u1edf d\u1ea1ng ti\u00eam d\u01b0\u1edbi da.<\/p>\n<h2><strong>\u0110i\u1ec1u g\u00ec s\u1ebd x\u1ea3y ra n\u1ebfu b\u1ecf l\u1ee1 m\u1ed9t li\u1ec1u?<\/strong><\/h2>\n<p>N\u1ebfu b\u1ea1n \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng trasuzumab trong nhi\u1ec1u th\u00e1ng, b\u1ea1n c\u00f3 th\u1ec3 mu\u1ed1n l\u1ee1 ho\u1eb7c tr\u00ec ho\u00e3n m\u1ed9t l\u1ea7n \u0111i\u1ec1u tr\u1ecb, v\u00ed d\u1ee5 \u0111\u1ec3 \u0111i ngh\u1ec9. N\u1ebfu b\u1ea1n mu\u1ed1n l\u00e0m vi\u1ec7c n\u00e0y th\u00ec h\u00e3y th\u1ea3o lu\u1eadn v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00e3.<strong>\u00a0<\/strong><\/p>\n<h2><strong>D\u00f9ng trastuzumab trong bao l\u00e2u?<\/strong><\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa nguy\u00ean ph\u00e1t: th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng trong 1 n\u0103m (ch\u1eebng 18 \u0111\u1ee3t).<\/p>\n<p>D\u00f9ng tr\u01b0\u1edbc ph\u1eabu thu\u1eadt: th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng 4-6 \u0111\u1ee3t.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa th\u1ee9 ph\u00e1t: th\u01b0\u1eddng \u0111\u01b0\u1ee3c d\u00f9ng khi thu\u1ed1c v\u1eabn ki\u1ec3m so\u00e1t ung th\u01b0.<\/p>\n<h2><strong>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a trastuzumab<\/strong><\/h2>\n<p>Gi\u1ed1ng nh\u01b0 b\u1ea5t k\u1ef3 \u0111i\u1ec1u tr\u1ecb n\u00e0o kh\u00e1c, trastuzumab c\u0169ng c\u00f3 th\u1ec3 g\u00e2y t\u00e1c d\u1ee5ng ph\u1ee5. M\u1ed7i ng\u01b0\u1eddi ph\u1ea3n \u1ee9ng kh\u00e1c nhau v\u1edbi thu\u1ed1c v\u00e0 m\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 h\u01a1n nh\u1eefng ng\u01b0\u1eddi kh\u00e1c. C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y c\u00f3 th\u1ec3 qu\u1ea3n l\u00fd \u0111\u01b0\u1ee3c v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 kh\u00f4ng ph\u1ea3i l\u00e0 s\u1ebd g\u1eb7p \u1edf t\u1ea5t c\u1ea3 m\u1ecdi ng\u01b0\u1eddi.<\/p>\n<p>N\u1ebfu b\u1ea1n c\u00f3 lo ng\u1ea1i v\u1ec1 b\u1ea5t k\u1ef3 t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o (k\u1ec3 c\u1ea3 ch\u01b0a \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea \u1edf \u0111\u00e2y) h\u00e3y n\u00f3i chuy\u1ec7n v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t.<\/p>\n<p><img decoding=\"async\" class=\"wp-image-41013 aligncenter\" src=\"https:\/\/yhoccongdong.com\/ung-thu\/wp-content\/uploads\/sites\/2\/2022\/05\/thong-tin-chung-ve-trastuzumab-3-300x250-1.png\" alt=\"\" width=\"600\" height=\"500\" \/><\/p>\n<h3><strong>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn<\/strong><\/h3>\n<h4><strong>C\u00e1c tri\u1ec7u ch\u1ee9ng gi\u1ed1ng nh\u01b0 c\u00fam<\/strong><\/h4>\n<p>S\u1ed1t, l\u1ea1nh run v\u00e0 \u0111au nh\u1eb9 \u1edf m\u1ed9t v\u00e0i b\u1ed9 ph\u1eadn c\u1ee7a c\u01a1 th\u1ec3 c\u00f3 th\u1ec3 x\u1ea3y ra trong ho\u1eb7c ngay sau \u0111i\u1ec1u tr\u1ecb. C\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y l\u00e0 ph\u1ed5 bi\u1ebfn h\u01a1n \u1edf l\u1ea7n \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean trastuzumab v\u00e0 th\u01b0\u1eddng kh\u00f4ng k\u00e9o d\u00e0i. C\u00f3 th\u1ec3 u\u1ed1ng thu\u1ed1c gi\u1ea3m \u0111au.<\/p>\n<h4><strong>Bu\u1ed3n n\u00f4n<\/strong><\/h4>\n<p>Tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng l\u00e0 nh\u1eb9 v\u00e0 kh\u00f4ng k\u00e9o d\u00e0i l\u00e2u. C\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh thu\u1ed1c ch\u1ed1ng m\u1ec7t m\u1ecfi \u0111\u1ec3 l\u00e0m gi\u1ea3m nh\u1eb9.<\/p>\n<h4><strong>Ti\u00eau ch\u1ea3y<\/strong><\/h4>\n<p>B\u1ea1n c\u00f3 th\u1ec3 b\u1ecb ti\u00eau ch\u1ea3y nh\u1eb9. B\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ho\u1eb7c b\u00e1c s\u0129 \u0111a khoa c\u00f3 th\u1ec3 k\u1ec3 \u0111\u01a1n thu\u1ed1c \u0111\u1ec3 gi\u00fap ki\u1ec3m so\u00e1t \u0111i\u1ec1u n\u00e0y. H\u00e3y li\u00ean l\u1ea1c v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb n\u1ebfu b\u1ea1n \u0111i ngo\u00e0i b\u1ed1n l\u1ea7n ho\u1eb7c nhi\u1ec1u h\u01a1n trong v\u00f2ng 24 gi\u1edd.<\/p>\n<h4><strong>\u0110au t\u1ea1i n\u01a1i ti\u00eam<\/strong><\/h4>\n<p>N\u1ebfu b\u1ea1n ti\u00eam trastuzumab d\u01b0\u1edbi da th\u00ec b\u1ea1n c\u00f3 th\u1ec3 \u0111au m\u1ed9t ch\u00fat \u1edf n\u01a1i ti\u00eam.<\/p>\n<h3><strong>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 \u00edt ph\u1ed5 bi\u1ebfn h\u01a1n<\/strong><\/h3>\n<p>Sau l\u1ea7n \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean b\u1ea1n c\u00f3 th\u1ec3 c\u00f3 c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c g\u1ed3m:<\/p>\n<ul>\n<li>\u0110au \u0111\u1ea7u<\/li>\n<li>Ch\u00f3ng m\u1eb7t<\/li>\n<li>\u0110au c\u01a1 v\u00e0 kh\u1edbp<\/li>\n<li>Ph\u00e1t ban<\/li>\n<li>N\u00f4n m\u1eeda<\/li>\n<li>Kh\u00f3 th\u1edf<\/li>\n<\/ul>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y th\u01b0\u1eddng l\u00e0 nh\u1eb9 v\u00e0 kh\u00f4ng ti\u1ebfp t\u1ee5c trong c\u00e1c l\u1ea7n \u0111i\u1ec1u tr\u1ecb sau.<\/p>\n<h3><strong>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 hi\u1ebfm g\u1eb7p<\/strong><\/h3>\n<h4><strong>Ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng<\/strong><\/h4>\n<p>N\u1ebfu b\u1ea1n c\u00f3 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng v\u1edbi trastuzumab th\u00ec ch\u1eafc n\u00f3 s\u1ebd x\u1ea3y ra trong v\u00f2ng v\u00e0i gi\u1edd \u0111\u1ea7u sau \u0111i\u1ec1u tr\u1ecb v\u00e0 nhi\u1ec1u kh\u1ea3 n\u0103ng nh\u1ea5t s\u1ebd l\u00e0 l\u1ea7n d\u00f9ng thu\u1ed1c \u0111\u1ea7u ti\u00ean ho\u1eb7c th\u1ee9 hai. Ph\u1ea3n \u1ee9ng c\u00f3 th\u1ec3 t\u1eeb nh\u1eb9 t\u1edbi nghi\u00eam tr\u1ecdng, nh\u01b0ng c\u00e1c ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng l\u00e0 kh\u00f4ng ph\u1ed5 bi\u1ebfn.<\/p>\n<p>B\u1ea1n s\u1ebd \u0111\u01b0\u1ee3c theo d\u00f5i k\u1ef9 trong khi \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 b\u1ea5t k\u1ef3 ph\u1ea3n \u1ee9ng n\u00e0o x\u1ea3y ra c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gi\u1ea3i quy\u1ebft ngay l\u1eadp t\u1ee9c. C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a d\u1ecb \u1ee9ng g\u1ed3m \u0111\u1ecf da, ph\u00e1t ban da, ng\u1ee9a, \u0111au l\u01b0ng, h\u01a1i th\u1edf ng\u1eafn, cho\u00e1ng, s\u1ed1t ho\u1eb7c l\u1ea1nh run. N\u1ebfu b\u1ea1n c\u00f3 ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng th\u00ec s\u1ebd d\u1eebng \u0111i\u1ec1u tr\u1ecb ngay.<\/p>\n<p>Thi tho\u1ea3ng c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y b\u1eaft \u0111\u1ea7u sau \u0111i\u1ec1u tr\u1ecb 6 gi\u1edd. N\u1ebfu vi\u1ec7c n\u00e0y x\u1ea3y ra h\u00e3y li\u00ean l\u1ea1c v\u1edbi b\u00e1c s\u0129 ngay l\u1eadp t\u1ee9c.<\/p>\n<h4><strong>C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim<\/strong><\/h4>\n<p>C\u00f3 kh\u1ea3 n\u0103ng th\u1ea5p x\u1ea3y ra c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim nh\u01b0 l\u00e0 nh\u1ecbp tim b\u1ea5t th\u01b0\u1eddng, c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 l\u00e0 kh\u00f3 th\u1edf v\u00e0 tim \u0111\u1eadp nhanh, kh\u00f3 ch\u1ecbu \u1edf ng\u1ef1c ho\u1eb7c c\u1ea3m gi\u00e1c nh\u01b0 tim \u0111ang \u0111\u1eadp d\u1ed3n d\u1eadp.<\/p>\n<p>C\u00e1c x\u00e9t nghi\u1ec7m ki\u1ec3m tra tim l\u00e0m vi\u1ec7c nh\u01b0 th\u1ebf n\u00e0o nh\u01b0 l\u00e0 si\u00eau \u00e2m tim ho\u1eb7c MUGA scan (s\u1eed d\u1ee5ng m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf v\u1eadt li\u1ec7u ph\u00f3ng x\u1ea1) th\u01b0\u1eddng \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>B\u1ea1n c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c \u0111\u01b0\u1ee3c x\u00e9t nghi\u1ec7m (th\u01b0\u1eddng l\u00e0 si\u00eau \u00e2m tim) m\u1ed7i ba th\u00e1ng trong khi \u0111ang \u0111i\u1ec1u tr\u1ecb, v\u00e0 m\u1ed7i s\u00e1u th\u00e1ng trong hai n\u0103m sau li\u1ec1u trastuzumab cu\u1ed1i c\u00f9ng.<\/p>\n<p>C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim nhi\u1ec1u kh\u1ea3 n\u0103ng x\u1ea3y ra h\u01a1n khi trastuzumab \u0111\u01b0\u1ee3c truy\u1ec1n \u0111\u1ed3ng th\u1eddi v\u1edbi h\u00f3a tr\u1ecb ho\u1eb7c n\u1ebfu b\u1ea1n \u0111\u00e3 c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 tim.<\/p>\n<p>N\u1ebfu b\u1ea1n g\u1eb7p v\u1ea5n \u0111\u1ec1 v\u1ec1 tim, \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c t\u1ea1m th\u1eddi d\u1eebng l\u1ea1i. \u0110\u00f4i khi c\u00f3 th\u1ec3 c\u1ea7n d\u1eebng v\u0129nh vi\u1ec5n. B\u1ea1n c\u00f3 th\u1ec3 c\u1ea7n \u0111i\u1ec1u tr\u1ecb b\u1ec7nh tim g\u00e2y ra do d\u00f9ng trastuzumab.<\/p>\n<p>Ch\u1ec9 r\u1ea5t \u00edt ng\u01b0\u1eddi truy\u1ec1n trastuzumab c\u00f3 v\u1ea5n \u0111\u1ec1 v\u1ec1 tim v\u00e0 th\u01b0\u1eddng h\u1ecd h\u1ed3i ph\u1ee5c sau khi \u0111i\u1ec1u tr\u1ecb k\u1ebft th\u00fac.<\/p>\n<h2><strong>C\u00f3 thai, tr\u00e1nh thai v\u00e0 nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9<\/strong><\/h2>\n<p>Trastuzumab kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong khi mang thai v\u00e0 ph\u1ee5 n\u1eef \u0111\u01b0\u1ee3c khuy\u00ean kh\u00f4ng mang thai khi s\u1eed d\u1ee5ng thu\u1ed1c do thu\u1ed1c c\u00f3 th\u1ec3 nguy h\u1ea1i cho thai nhi \u0111ang ph\u00e1t tri\u1ec3n. M\u1ed9t s\u1ed1 ph\u1ee5 n\u1eef v\u1eabn c\u00f3 th\u1ec3 c\u00f3 thai th\u1eadm ch\u00ed n\u1ebfu kinh nguy\u1ec7t c\u1ee7a h\u1ecd kh\u00f4ng \u0111\u1ec1u ho\u1eb7c \u0111\u00e3 d\u1eebng, n\u00ean c\u1ea7n d\u00f9ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai c\u00f3 hi\u1ec7u qu\u1ea3 nh\u01b0 l\u00e0 bao cao su trong \u00edt nh\u1ea5t b\u1ea3y th\u00e1ng sau khi k\u1ebft th\u00fac \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9 c\u0169ng kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb trong khi \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng trastuzumab ho\u1eb7c trong v\u00f2ng b\u1ea3y th\u00e1ng sau li\u1ec1u cu\u1ed1i c\u00f9ng.<\/p>\n<h2><strong>\u0110i du l\u1ecbch v\u00e0 ti\u00eam v\u1eafc xin<\/strong><\/h2>\n<p>Ph\u1ee5 thu\u1ed9c v\u00e0o b\u1ea1n \u0111ang d\u00f9ng trastuzumab ho\u1eb7c kh\u00f4ng d\u00f9ng trastuzumab c\u00f9ng v\u1edbi h\u00f3a tr\u1ecb ho\u1eb7c ti\u1ebfp theo h\u00f3a tr\u1ecb, b\u1ea1n c\u00f3 th\u1ec3 ho\u1eb7c kh\u00f4ng th\u1ec3 ti\u00eam v\u1eafc xin du l\u1ecbch ho\u1eb7c v\u1eafc xin th\u01b0\u1eddng quy. N\u1ebfu b\u1ea1n c\u1ea7n ti\u00eam v\u1eafc xin, h\u00e3y th\u1ea3o lu\u1eadn v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc ti\u00ean.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p><a href=\"https:\/\/breastcancernow.org\/sites\/default\/files\/publications\/pdf\/bcc41_trastuzumab_herceptin_2019_web.pdf\" target=\"_blank\" rel=\"noopener\">https:\/\/breastcancernow.org\/sites\/default\/files\/publications\/pdf\/bcc41_trastuzumab_herceptin_2019_web.pdf<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trastuzumab l\u00e0 thu\u1ed1c s\u1eed d\u1ee5ng trong li\u1ec7u ph\u00e1p \u0111\u00edch (li\u1ec7u ph\u00e1p sinh h\u1ecdc). C\u00e1c li\u1ec7u ph\u00e1p \u0111\u00edch ch\u1eb7n s\u1ef1 ph\u00e1t tri\u1ec3n v\u00e0 lan t\u1ecfa c\u1ee7a ung th\u01b0. Ch\u00fang nh\u1eafm \u0111\u1ebfn v\u00e0 can thi\u1ec7p v\u00e0o qu\u00e1 tr\u00ecnh trong c\u00e1c t\u1ebf b\u00e0o gi\u00fap ung th\u01b0 ph\u00e1t tri\u1ec3n.<\/p>\n","protected":false},"author":548,"featured_media":9240,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2594],"tags":[3219,2569],"series":[1428],"coauthors":[1189],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Th\u00f4ng tin chung v\u1ec1 Trastuzumab - D\u1ef1 \u00e1n Ung Th\u01b0<\/title>\n<meta name=\"description\" content=\"Th\u00f4ng tin chung v\u1ec1 Trastuzumab - D\u1ef1 \u00e1n Ung Th\u01b0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/yhoccongdong.com\/ung-thu\/thong-tin-chung-ve-trastuzumab\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Th\u00f4ng tin chung v\u1ec1 Trastuzumab - 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